2325: Steroid therapy limits stem cell activation required to enact mucosal healing in inflammatory bowel disease

por Brady Lynch, Evan, Goretsky, Tatiana, Bradford, Emily, Gao, Tianyan, Barrett, Terrence
Publicado 2018

PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells

por Smith, Alena J., Wen, Yang-An, Stevens, Payton D., Liu, Jingpeng, Wang, Chi, Gao, Tianyan
Publicado 2016

PHLPP regulates hexokinase 2-dependent glucose metabolism in colon cancer cells

por Xiong, Xiaopeng, Wen, Yang-An, Mitov, Mihail I, C Oaks, Mary, Miyamoto, Shigeki, Gao, Tianyan
Publicado 2017

Loss of PHLPP expression in colon cancer: Role in proliferation and tumorigenesis

por Liu, Jianyu, Weiss, Heidi L., Rychahou, Piotr, Jackson, Lindsey N., Evers, B. Mark, Gao, Tianyan
Publicado 2008

The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer

por Li, Xin, Stevens, Payton D., Yang, Haihua, Gulhati, Pat, Wang, Wei, Evers, B. Mark, Gao, Tianyan
Publicado 2012

Downregulation of PHLPP induced by endoplasmic reticulum stress promotes eIF2α phosphorylation and chemoresistance in colon cancer

por Guo, Bianqin, Xiong, Xiaopeng, Hasani, Sumati, Wen, Yang-An, Li, Austin T., Martinez, Rebecca, Skaggs, Ashley T., Gao, Tianyan
Publicado 2021

Upregulation of CPT1A is essential for the tumor-promoting effect of adipocytes in colon cancer

por Xiong, Xiaopeng, Wen, Yang-An, Fairchild, Rachelle, Zaytseva, Yekaterina Y., Weiss, Heidi L., Evers, B. Mark, Gao, Tianyan
Publicado 2020

Critical Role of PI3K/Akt/GSK3β in Motoneuron Specification from Human Neural Stem Cells in Response to FGF2 and EGF

por Ojeda, Luis, Gao, Junling, Hooten, Kristopher G., Wang, Enyin, Thonhoff, Jason R., Dunn, Tiffany J., Gao, Tianyan, Wu, Ping
Publicado 2011

DNA polymerase gamma (Polγ) deficiency triggers a selective mTORC2 prosurvival autophagy response via mitochondria-mediated ROS signaling

por Dhar, Sanjit K., Bakthavatchalu, Vasudevan, Dhar, Bithika, Chen, Jing, Tadahide, Izumi, Zhu, Haining, Gao, Tianyan, St. Clair, Daret K.
Publicado 2018

Na/K-ATPase Y260 Phosphorylation–mediated Src Regulation in Control of Aerobic Glycolysis and Tumor Growth

por Banerjee, Moumita, Cui, Xiaoyu, Li, Zhichuan, Yu, Hui, Cai, Liquan, Jia, Xuelian, He, Daheng, Wang, Chi, Gao, Tianyan, Xie, Zijian
Publicado 2018

Detection of PHLPP1α/β in Human and Mouse Brain by Different Anti-PHLPP1 Antibodies

por Jackson, Travis C., Bayir, Hülya, Ikonomovic, Milos D., Janesko-Feldman, Keri, Mi, Zaichuan, Gao, Tianyan, Jackson, Edwin K., Kochanek, Patrick M.
Publicado 2015

Kinase suppressor of Ras 1 and Exo70 promote fatty acid-stimulated neurotensin secretion through ERK1/2 signaling

por Rock, Stephanie, Li, Xian, Song, Jun, Townsend, Courtney M., Weiss, Heidi L., Rychahou, Piotr, Gao, Tianyan, Li, Jing, Evers, B. Mark
Publicado 2019

Collagen prolyl 4-hydroxylase 1 is essential for HIF-1α stabilization and TNBC chemoresistance

por Xiong, Gaofeng, Stewart, Rachel L., Chen, Jie, Gao, Tianyan, Scott, Timothy L., Samayoa, Luis M., O’Connor, Kathleen, Lane, Andrew N., Xu, Ren
Publicado 2018

Neurotensin Regulates Proliferation and Stem Cell Function in the Small Intestine in a Nutrient-Dependent Manner

por Rock, Stephanie A., Jiang, Kai, Wu, Yuanyuan, Liu, Yajuan, Li, Jing, Weiss, Heidi L., Wang, Chi, Jia, Jianhang, Gao, Tianyan, Evers, B. Mark
Publicado 2021

Adipocytes activate mitochondrial fatty acid oxidation and autophagy to promote tumor growth in colon cancer

por Wen, Yang-An, Xing, Xiaopeng, Harris, Jennifer W, Zaytseva, Yekaterina Y, Mitov, Mihail I, Napier, Dana L, Weiss, Heidi L, Mark Evers, B, Gao, Tianyan
Publicado 2017

Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer

por Wen, Yang-An, Xiong, Xiaopeng, Zaytseva, Yekaterina Y., Napier, Dana L., Vallee, Emma, Li, Austin T., Wang, Chi, Weiss, Heidi L., Evers, B. Mark, Gao, Tianyan
Publicado 2018

Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration

por Zaytseva, Yekaterina Y., Harris, Jennifer W., Mitov, Mihail I., Kim, Ji Tae, Butterfield, D. Allan, Lee, Eun Y., Weiss, Heidi L., Gao, Tianyan, Evers, B. Mark
Publicado 2015

Inhibition of Protein Tyrosine Phosphatase Receptor Type F Suppresses Wnt Signaling in Colorectal Cancer

por Gan, Tong, Stevens, Ashley T., Xiong, Xiaopeng, Wen, Yang-An, Farmer, Trevor N., Li, Austin T., Stevens, Payton D., Golshani, Sanam, Weiss, Heidi L., Evers, B. Mark, Gao, Tianyan
Publicado 2020

Inhibition of mitochondrial fission activates glycogen synthesis to support cell survival in colon cancer

por Hasani, Sumati, Young, Lyndsay E. A., Van Nort, Warren, Banerjee, Moumita, Rivas, Dylan R., Kim, Jinhwan, Xiong, Xiaopeng, Sun, Ramon C., Gentry, Matthew S., Sesaki, Hiromi, Gao, Tianyan
Publicado 2023

Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice

por Liu, Yi, Zhang, Cuiping, Li, Zhenyu, Wang, Chi, Jia, Jianhang, Gao, Tianyan, Hildebrandt, Gerhard, Zhou, Daohong, Bondada, Subbarao, Ji, Peng, St. Clair, Daret, Liu, Jinze, Zhan, Changguo, Geiger, Hartmut, Wang, Shuxia, Liang, Ying
Publicado 2017