Loss of ATRX confers DNA repair defects and PARP inhibitor sensitivity

por Garbarino, Jennifer, Eckroate, Jillian, Sundaram, Ranjini K., Jensen, Ryan B., Bindra, Ranjit S.
Publicado 2021

The Pathogenic R3052W BRCA2 Variant Disrupts Homology-Directed Repair by Failing to Localize to the Nucleus

por Jimenez-Sainz, Judit, Krysztofiak, Adam, Garbarino, Jennifer, Rogers, Faye, Jensen, Ryan B.
Publicado 2022

BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair

por Jimenez-Sainz, Judit, Mathew, Joshua, Moore, Gemma, Lahiri, Sudipta, Garbarino, Jennifer, Eder, Joseph P, Rothenberg, Eli, Jensen, Ryan B
Publicado 2022

Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly

por Cicconi, Alessandro, Rai, Rekha, Xiong, Xuexue, Broton, Cayla, Al-Hiyasat, Amer, Hu, Chunyi, Dong, Siying, Sun, Wenqi, Garbarino, Jennifer, Bindra, Ranjit S., Schildkraut, Carl, Chen, Yong, Chang, Sandy
Publicado 2020