Tumor Microenvironment-Derived Metabolites: A Guide to Find New Metabolic Therapeutic Targets and Biomarkers

por García-Cañaveras, Juan C., Lahoz, Agustín
Publicado 2021

FAMetA: a mass isotopologue-based tool for the comprehensive analysis of fatty acid metabolism

por Alcoriza-Balaguer, María I, García-Cañaveras, Juan C, Benet, Marta, Juan-Vidal, Oscar, Lahoz, Agustín
Publicado 2023

SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia

por García-Cañaveras, Juan C., Lancho, Olga, Ducker, Gregory S., Ghergurovich, Jonathan M., Xu, Xincheng, da Silva-Diz, Victoria, Minuzzo, Sonia, Indraccolo, Stefano, Kim, Hahn, Herranz, Daniel, Rabinowitz, Joshua D.
Publicado 2020

PPARγ is a nexus controlling alternative activation of macrophages via glutamine metabolism

por Nelson, Victoria L., Nguyen, Hoang C.B., Garcìa-Cañaveras, Juan C., Briggs, Erika R., Ho, Wesley Y., DiSpirito, Joanna R., Marinis, Jill M., Hill, David A., Lazar, Mitchell A.
Publicado 2018

CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production

por Garcia-Canaveras, Juan C., Heo, David, Trefely, Sophie, Leferovich, John, Xu, Chong, Philipson, Benjamin I., Ghassemi, Saba, Milone, Michael C., Moon, Edmund K., Snyder, Nathaniel W., June, Carl H., Rabinowitz, Joshua D., O’Connor, Roddy S.
Publicado 2021

A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway

por Ghergurovich, Jonathan M., García-Cañaveras, Juan C., Wang, Joshua, Schmidt, Emily, Zhang, Zhaoyue, TeSlaa, Tara, Patel, Harshel, Chen, Li, Britt, Emily C., Piqueras-Nebot, Marta, Gomez-Cabrera, Mari Carmen, Lahoz, Agustín, Fan, Jing, Beier, Ulf H, Kim, Hahn, Rabinowitz, Joshua D.
Publicado 2020