Dual mTORC1/C2 inhibitors: gerosuppressors with potential anti-aging effect

por Sousa-Victor, Pedro, García-Prat, Laura, Muñoz-Cánoves, Pura
Publicado 2015

Autophagy: a decisive process for stemness

por García-Prat, Laura, Martínez-Vicente, Marta, Muñoz-Cánoves, Pura
Publicado 2016

Computational modelling of stem cell–niche interactions facilitates discovery of strategies to enhance tissue regeneration and counteract ageing

por Potapov, Ilya, García‐Prat, Laura, Ravichandran, Srikanth, Muñoz‐Cánoves, Pura, del Sol, Antonio
Publicado 2021

Protocol for RNA-seq library preparation starting from a rare muscle stem cell population or a limited number of mouse embryonic stem cells

por Dell’Orso, Stefania, Juan, Aster H., Moiseeva, Victoria, García-Prat, Laura, Muñoz-Cánoves, Pura, Sartorelli, Vittorio
Publicado 2021

Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals

por Segalés, Jessica, Perdiguero, Eusebio, Serrano, Antonio L., Sousa-Victor, Pedro, Ortet, Laura, Jardí, Mercè, Budanov, Andrei V., Garcia-Prat, Laura, Sandri, Marco, Thomson, David M., Karin, Michael, Hee Lee, Jun, Muñoz-Cánoves, Pura
Publicado 2020

Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal

por Xie, Stephanie Z., Garcia-Prat, Laura, Voisin, Veronique, Ferrari, Robin, Gan, Olga I., Wagenblast, Elvin, Kaufmann, Kerstin B., Zeng, Andy G.X., Takayanagi, Shin-ichiro, Patel, Ishita, Lee, Esther K., Jargstorf, Joseph, Holmes, Gareth, Romm, Guy, Pan, Kristele, Shoong, Michelle, Vedi, Aditi, Luberto, Chiara, Minden, Mark D., Bader, Gary D., Laurenti, Elisa, Dick, John E.
Publicado 2019

Biological and therapeutic implications of a unique subtype of NPM1 mutated AML

por Mer, Arvind Singh, Heath, Emily M., Madani Tonekaboni, Seyed Ali, Dogan-Artun, Nergiz, Nair, Sisira Kadambat, Murison, Alex, Garcia-Prat, Laura, Shlush, Liran, Hurren, Rose, Voisin, Veronique, Bader, Gary D., Nislow, Corey, Rantalainen, Mattias, Lehmann, Soren, Gower, Mark, Guidos, Cynthia J., Lupien, Mathieu, Dick, John E., Minden, Mark D., Schimmer, Aaron D., Haibe-Kains, Benjamin
Publicado 2021

Transcriptomic classes of BCR-ABL1 lymphoblastic leukemia

por Kim, Jaeseung C., Chan-Seng-Yue, Michelle, Ge, Sabrina, Zeng, Andy G. X., Ng, Karen, Gan, Olga I., Garcia-Prat, Laura, Flores-Figueroa, Eugenia, Woo, Tristan, Zhang, Amy Xin Wei, Arruda, Andrea, Chithambaram, Shivapriya, Dobson, Stephanie M., Khoo, Amanda, Khan, Shahbaz, Ibrahimova, Narmin, George, Ann, Tierens, Anne, Hitzler, Johann, Kislinger, Thomas, Dick, John E., McPherson, John D., Minden, Mark D., Notta, Faiyaz
Publicado 2023

The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness

por Thomas, Geethu Emily, Egan, Grace, García-Prat, Laura, Botham, Aaron, Voisin, Veronique, Patel, Parasvi S., Hoff, Fieke W., Chin, Jordan, Nachmias, Boaz, Kaufmann, Kerstin B., Khan, Dilshad H., Hurren, Rose, Wang, Xiaoming, Gronda, Marcela, MacLean, Neil, O’Brien, Cristiana, Singh, Rashim P., Jones, Courtney L., Harding, Shane M., Raught, Brian, Arruda, Andrea, Minden, Mark D., Bader, Gary D., Hakem, Razq, Kornblau, Steve, Dick, John E., Schimmer, Aaron D.
Publicado 2022

Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy

por Marone, Romina, Landmann, Emmanuelle, Devaux, Anna, Lepore, Rosalba, Seyres, Denis, Zuin, Jessica, Burgold, Thomas, Engdahl, Corinne, Capoferri, Giuseppina, Dell’Aglio, Alessandro, Larrue, Clément, Simonetta, Federico, Rositzka, Julia, Rhiel, Manuel, Andrieux, Geoffroy, Gallagher, Danielle N., Schröder, Markus S., Wiederkehr, Amélie, Sinopoli, Alessandro, Do Sacramento, Valentin, Haydn, Anna, Garcia-Prat, Laura, Divsalar, Christopher, Camus, Anna, Xu, Liwen, Bordoli, Lorenza, Schwede, Torsten, Porteus, Matthew, Tamburini, Jérôme, Corn, Jacob E., Cathomen, Toni, Cornu, Tatjana I., Urlinger, Stefanie, Jeker, Lukas T.
Publicado 2023