SIRT1/2 orchestrate acquisition of DNA methylation and loss of histone H3 activating marks to prevent premature activation of inflammatory genes in macrophages

por Li, Tianlu, Garcia-Gomez, Antonio, Morante-Palacios, Octavio, Ciudad, Laura, Özkaramehmet, Sevgi, Van Dijck, Evelien, Rodríguez-Ubreva, Javier, Vaquero, Alejandro, Ballestar, Esteban
Publicado 2020

TET2- and TDG-mediated changes are required for the acquisition of distinct histone modifications in divergent terminal differentiation of myeloid cells

por Garcia-Gomez, Antonio, Li, Tianlu, Kerick, Martin, Català-Moll, Francesc, Comet, Natalia R., Rodríguez-Ubreva, Javier, de la Rica, Lorenzo, Branco, Miguel R., Martín, Javier, Ballestar, Esteban
Publicado 2017

Lysyl oxidase-like 3 is required for melanoma cell survival by maintaining genomic stability

por Santamaría, Patricia G., Floristán, Alfredo, Fontanals-Cirera, Bárbara, Vázquez-Naharro, Alberto, Santos, Vanesa, Morales, Saleta, Yuste, Lourdes, Peinado, Héctor, García-Gómez, Antonio, Portillo, Francisco, Hernando, Eva, Cano, Amparo
Publicado 2017

NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation

por de la Rica, Lorenzo, García-Gómez, Antonio, Comet, Natalia R, Rodríguez-Ubreva, Javier, Ciudad, Laura, Vento-Tormo, Roser, Company, Carlos, Álvarez-Errico, Damiana, García, Mireia, Gómez-Vaquero, Carmen, Ballestar, Esteban
Publicado 2015

Transcriptomic profile induced in bone marrow mesenchymal stromal cells after interaction with multiple myeloma cells: implications in myeloma progression and myeloma bone disease

por Garcia-Gomez, Antonio, Las Rivas, Javier De, Ocio, Enrique M., Díaz-Rodríguez, Elena, Montero, Juan C., Martín, Montserrat, Blanco, Juan F., Sanchez-Guijo, Fermín M., Pandiella, Atanasio, San Miguel, Jesús F., Garayoa, Mercedes
Publicado 2014

JAK2-STAT Epigenetically Regulates Tolerized Genes in Monocytes in the First Encounter With Gram-Negative Bacterial Endotoxins in Sepsis

por Morante-Palacios, Octavio, Lorente-Sorolla, Clara, Ciudad, Laura, Calafell-Segura, Josep, Garcia-Gomez, Antonio, Català-Moll, Francesc, Ruiz-Sanmartín, Adolfo, Martínez-Gallo, Mónica, Ferrer, Ricard, Ruiz-Rodriguez, Juan Carlos, Álvarez-Errico, Damiana, Ballestar, Esteban
Publicado 2021

Dasatinib as a Bone-Modifying Agent: Anabolic and Anti-Resorptive Effects

por Garcia-Gomez, Antonio, Ocio, Enrique M., Crusoe, Edvan, Santamaria, Carlos, Hernández-Campo, Pilar, Blanco, Juan F., Sanchez-Guijo, Fermin M., Hernández-Iglesias, Teresa, Briñón, Jesús G., Fisac-Herrero, Rosa M., Lee, Francis Y., Pandiella, Atanasio, San Miguel, Jesús F., Garayoa, Mercedes
Publicado 2012

Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites

por Rodríguez-Cortez, Virginia C., Martínez-Redondo, Paloma, Català-Moll, Francesc, Rodríguez-Ubreva, Javier, Garcia-Gomez, Antonio, Poorani-Subramani, Ganesh, Ciudad, Laura, Hernando, Henar, Pérez-García, Arantxa, Company, Carlos, Urquiza, José M., Ramiro, Almudena R., Di Noia, Javier M., Vaquero, Alejandro, Ballestar, Esteban
Publicado 2017

Inflammatory cytokines and organ dysfunction associate with the aberrant DNA methylome of monocytes in sepsis

por Lorente-Sorolla, Clara, Garcia-Gomez, Antonio, Català-Moll, Francesc, Toledano, Víctor, Ciudad, Laura, Avendaño-Ortiz, José, Maroun-Eid, Charbel, Martín-Quirós, Alejandro, Martínez-Gallo, Mónica, Ruiz-Sanmartín, Adolfo, del Campo, Álvaro García, Ferrer-Roca, Ricard, Ruiz-Rodriguez, Juan Carlos, Álvarez-Errico, Damiana, López-Collazo, Eduardo, Ballestar, Esteban
Publicado 2019

Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease

por Garcia-Gomez, Antonio, Li, Tianlu, de la Calle-Fabregat, Carlos, Rodríguez-Ubreva, Javier, Ciudad, Laura, Català-Moll, Francesc, Godoy-Tena, Gerard, Martín-Sánchez, Montserrat, San-Segundo, Laura, Muntión, Sandra, Morales, Xabier, Ortiz-de-Solórzano, Carlos, Oyarzabal, Julen, San José-Enériz, Edurne, Esteller, Manel, Agirre, Xabier, Prosper, Felipe, Garayoa, Mercedes, Ballestar, Esteban
Publicado 2021

STATegra, a comprehensive multi-omics dataset of B-cell differentiation in mouse

por Gomez-Cabrero, David, Tarazona, Sonia, Ferreirós-Vidal, Isabel, Ramirez, Ricardo N., Company, Carlos, Schmidt, Andreas, Reijmers, Theo, Paul, Veronica von Saint, Marabita, Francesco, Rodríguez-Ubreva, Javier, Garcia-Gomez, Antonio, Carroll, Thomas, Cooper, Lee, Liang, Ziwei, Dharmalingam, Gopuraja, van der Kloet, Frans, Harms, Amy C., Balzano-Nogueira, Leandro, Lagani, Vincenzo, Tsamardinos, Ioannis, Lappe, Michael, Maier, Dieter, Westerhuis, Johan A., Hankemeier, Thomas, Imhof, Axel, Ballestar, Esteban, Mortazavi, Ali, Merkenschlager, Matthias, Tegner, Jesper, Conesa, Ana
Publicado 2019