Macrocycles in Drug Discovery—Learning from the Past for the Future

por Garcia Jimenez, Diego, Poongavanam, Vasanthanathan, Kihlberg, Jan
Publicado 2023

PROTACs and Building Blocks: The 2D Chemical Space in Very Early Drug Discovery

por Ermondi, Giuseppe, Garcia-Jimenez, Diego, Caron, Giulia
Publicado 2021

Rational Control of Molecular Properties Is Mandatory to Exploit the Potential of PROTACs as Oral Drugs

por Ermondi, Giuseppe, Garcia Jimenez, Diego, Rossi Sebastiano, Matteo, Caron, Giulia
Publicado 2021

Refinement of Computational Access to Molecular Physicochemical Properties: From Ro5 to bRo5

por Rossi Sebastiano, Matteo, Garcia Jimenez, Diego, Vallaro, Maura, Caron, Giulia, Ermondi, Giuseppe
Publicado 2022

Designing Soluble PROTACs: Strategies and Preliminary Guidelines

por García Jiménez, Diego, Rossi Sebastiano, Matteo, Vallaro, Maura, Mileo, Valentina, Pizzirani, Daniela, Moretti, Elisa, Ermondi, Giuseppe, Caron, Giulia
Publicado 2022

Chamelogk: A Chromatographic Chameleonicity Quantifier to Design Orally Bioavailable Beyond-Rule-of-5 Drugs

por Garcia Jimenez, Diego, Vallaro, Maura, Rossi Sebastiano, Matteo, Apprato, Giulia, D’Agostini, Giulia, Rossetti, Paolo, Ermondi, Giuseppe, Caron, Giulia
Publicado 2023