Bone morphogenetic protein receptor signal transduction in human disease

por Gomez‐Puerto, Maria Catalina, Iyengar, Prasanna Vasudevan, García de Vinuesa, Amaya, ten Dijke, Peter, Sanchez‐Duffhues, Gonzalo
Publicado 2018

TGFβ1-induced SMAD2/3 and SMAD1/5 phosphorylation are both ALK5-kinase-dependent in primary chondrocytes and mediated by TAK1 kinase activity

por van Caam, Arjan, Madej, Wojciech, Garcia de Vinuesa, Amaya, Goumans, Marie-José, ten Dijke, Peter, Blaney Davidson, Esmeralda, van der Kraan, Peter
Publicado 2017

Disparate phospho-Smad2 levels in advanced type 2 diabetes patients with diabetic nephropathy and early experimental db/db mouse model

por Thomsen, Lise Høj, Fog-Tonnesen, Morten, Nielsen Fink, Lisbeth, Norlin, Jenny, García de Vinuesa, Amaya, Hansen, Troels Krarup, de Heer, Emile, ten Dijke, Peter, Rosendahl, Alexander
Publicado 2017

Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis

por Garcia de Vinuesa, Amaya, Sanchez‐Duffhues, Gonzalo, Blaney‐Davidson, Esmeralda, van Caam, Arjan, Lodder, Kirsten, Ramos, Yolande, Kloppenburg, Margreet, Meulenbelt, Ingrid, van der Kraan, Peter, Goumans, Marie‐José, ten Dijke, Peter
Publicado 2021

Inflammation induces endothelial‐to‐mesenchymal transition and promotes vascular calcification through downregulation of BMPR2

por Sánchez‐Duffhues, Gonzalo, García de Vinuesa, Amaya, van de Pol, Vera, Geerts, Marlieke E, de Vries, Margreet R, Janson, Stef GT, van Dam, Hans, Lindeman, Jan H., Goumans, Marie‐José, ten Dijke, Peter
Publicado 2019

Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva‐Derived Endothelial Cells

por Sánchez‐Duffhues, Gonzalo, Williams, Eleanor, Benderitter, Pascal, Orlova, Valeria, van Wijhe, Michiel, Garcia de Vinuesa, Amaya, Kerr, Georgina, Caradec, Josselin, Lodder, Kirsten, de Boer, Hetty C., Goumans, Marie‐José, Eekhoff, Elisabeth M W, Morales‐Piga, Antonio, Bachiller‐Corral, Javier, Koolwijk, Pieter, Bullock, Alex N., Hoflack, Jan, ten Dijke, Peter
Publicado 2019