Mechanistic Multiscale Pharmacokinetic Model for the Anticancer Drug 2’,2’‐difluorodeoxycytidine (Gemcitabine) in Pancreatic Cancer

por Garcia‐Cremades, Maria, Melillo, Nicola, Troconiz, Iñaki F., Magni, Paolo
Publicado 2020

Clinical Pharmacokinetics of Oral Sodium Selenite and Dosing Implications in the Treatment of Patients with Metastatic Cancer

por Jayachandran, Priya, Knox, Susan J., Garcia-Cremades, Maria, Savić, Radojka M.
Publicado 2021

Editorial: Innovative pharmacometric approaches to inform drug development and clinical use

por Garcia-Cremades, Maria, Parra-Guillen, Zinnia P., Mangas-Sanjuan, Victor, Geerts, Hugo
Publicado 2023

Response to “Quantitative Clinical Pharmacology INPUT to SARS‐CoV‐2 Therapeutics Should be Based on Robust Data”

por Garcia‐Cremades, Maria, Solans, Belen P., Hughes, Emma, Ernest, Jacqueline P., Wallender, Erika, Savic, Radojka M.
Publicado 2020

A Mechanistic In Vivo/Ex Vivo Pharmacokinetic‐Pharmacodynamic Model of Tenofovir for HIV Prevention

por Jayachandran, Priya, Garcia-Cremades, Maria, Vučićević, Katarina, Bumpus, Namandjé N., Anton, Peter, Hendrix, Craig, Savić, Radojka
Publicado 2021

Oxypurinol pharmacokinetics and pharmacodynamics in healthy volunteers: Influence of BCRP Q141K polymorphism and patient characteristics

por Vora, Bianca, Brackman, Deanna J., Zou, Ling, Garcia‐Cremades, Maria, Sirota, Marina, Savic, Radojka M., Giacomini, Kathleen M.
Publicado 2021

Population Pharmacokinetic/Pharmacodynamic Modelling of Daptomycin for Schedule Optimization in Patients with Renal Impairment

por García-Martínez, Teresa, Bellés-Medall, María Dolores, García-Cremades, Maria, Ferrando-Piqueres, Raúl, Mangas-Sanjuán, Victor, Merino-Sanjuan, Matilde
Publicado 2022

Optimizing Hydroxychloroquine Dosing for Patients With COVID‐19: An Integrative Modeling Approach for Effective Drug Repurposing

por Garcia‐Cremades, Maria, Solans, Belen P., Hughes, Emma, Ernest, Jacqueline P., Wallender, Erika, Aweeka, Francesca, Luetkemeyer, Anne F., Savic, Radojka M.
Publicado 2020

Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies

por Garcia-Prats, Anthony J., Schaaf, H. Simon, Draper, Heather R., Garcia-Cremades, Maria, Winckler, Jana, Wiesner, Lubbe, Hesseling, Anneke C., Savic, Rada M.
Publicado 2019

Modeling the Probability of HIV Infection over Time in High-Risk Seronegative Participants Receiving Placebo in Five Randomized Double-Blind Placebo-Controlled HIV Pre-Exposure Pro...

por Garcia-Cremades, Maria, Hendrix, Craig W., Jayachandran, Priya, Strydom, Natasha, Jarlsberg, Leah, Grant, Robert, Celum, Connie L., Martin, Michael, Baeten, Jared M., Marrazzo, Jeanne, Anderson, Peter, Choopanya, Kachit, Vanichseni, Suphak, Glidden, David V., Savic, Radojka M.
Publicado 2022

Combination of Mycobacterium tuberculosis RS Ratio and CFU Improves the Ability of Murine Efficacy Experiments to Distinguish between Drug Treatments

por Dide-Agossou, Christian, Bauman, Allison A., Ramey, Michelle E., Rossmassler, Karen, Al Mubarak, Reem, Pauly, Samantha, Voskuil, Martin I., Garcia-Cremades, Maria, Savic, Rada M., Nahid, Payam, Moore, Camille M., Tasneen, Rokeya, Nuermberger, Eric L., Robertson, Gregory T., Walter, Nicholas D.
Publicado 2022

Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens

por Walter, Nicholas D., Born, Sarah E. M., Robertson, Gregory T., Reichlen, Matthew, Dide-Agossou, Christian, Ektnitphong, Victoria A., Rossmassler, Karen, Ramey, Michelle E., Bauman, Allison A., Ozols, Victor, Bearrows, Shelby C., Schoolnik, Gary, Dolganov, Gregory, Garcia, Benjamin, Musisi, Emmanuel, Worodria, William, Huang, Laurence, Davis, J. Lucian, Nguyen, Nhung V., Nguyen, Hung V., Nguyen, Anh T. V., Phan, Ha, Wilusz, Carol, Podell, Brendan K., Sanoussi, N’ Dira, de Jong, Bouke C., Merle, Corinne S., Affolabi, Dissou, McIlleron, Helen, Garcia-Cremades, Maria, Maidji, Ekaterina, Eshun-Wilson, Franceen, Aguilar-Rodriguez, Brandon, Karthikeyan, Dhuvarakesh, Mdluli, Khisimuzi, Bansbach, Cathy, Lenaerts, Anne J., Savic, Radojka M., Nahid, Payam, Vásquez, Joshua J., Voskuil, Martin I.
Publicado 2021