Leishmania donovani Develops Resistance to Drug Combinations

por García-Hernández, Raquel, Manzano, José Ignacio, Castanys, Santiago, Gamarro, Francisco
Publicado 2012

Fitness of Leishmania donovani Parasites Resistant to Drug Combinations

por García-Hernández, Raquel, Gómez-Pérez, Verónica, Castanys, Santiago, Gamarro, Francisco
Publicado 2015

Transcriptomic Analysis in Human Macrophages Infected with Therapeutic Failure Clinical Isolates of Leishmania infantum

por Perea-Martínez, Ana, García-Hernández, Raquel, Manzano, José Ignacio, Gamarro, Francisco
Publicado 2022

New Insights on Heme Uptake in Leishmania spp.

por Cabello-Donayre, María, Orrego, Lina M., Herráez, Elisa, García-Hernández, Raquel, Pérez-Victoria, José M.
Publicado 2022

Transcriptome Analysis of Intracellular Amastigotes of Clinical Leishmania infantum Lines from Therapeutic Failure Patients after Infection of Human Macrophages

por García-Hernández, Raquel, Perea-Martínez, Ana, Manzano, José Ignacio, Terrón-Camero, Laura C., Andrés-León, Eduardo, Gamarro, Francisco
Publicado 2022

Decreased antimony uptake and overexpression of genes of thiol metabolism are associated with drug resistance in a canine isolate of Leishmania infantum

por Gómez Pérez, Verónica, García-Hernandez, Raquel, Corpas-López, Victoriano, Tomás, Ana M., Martín-Sanchez, Joaquina, Castanys, Santiago, Gamarro, Francisco
Publicado 2016

Modulation of Cholesterol Pathways in Human Macrophages Infected by Clinical Isolates of Leishmania infantum

por Manzano, José Ignacio, Perea-Martínez, Ana, García-Hernández, Raquel, Andrés-León, Eduardo, Terrón-Camero, Laura C., Poveda, José Antonio, Gamarro, Francisco
Publicado 2022

Mapping microglia and astrocyte activation in vivo using diffusion MRI

por Garcia-Hernandez, Raquel, Cerdán Cerdá, Antonio, Trouve Carpena, Alejandro, Drakesmith, Mark, Koller, Kristin, Jones, Derek K., Canals, Santiago, De Santis, Silvia
Publicado 2022

Label-Free Mass Spectrometry Proteomics Reveals Different Pathways Modulated in THP-1 Cells Infected with Therapeutic Failure and Drug Resistance Leishmania infantum Clinical Isola...

por Tagliazucchi, Lorenzo, Perea-Martinez, Ana, Fiorini, Greta, Manzano, José Ignacio, Genovese, Filippo, García-Hernández, Raquel, Pinetti, Diego, Gamarro, Francisco, Costi, Maria Paola
Publicado 2023

Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp(2)-Iminosugar Glycolipids

por Sánchez-Fernández, Elena M., García-Moreno, M. Isabel, García-Hernández, Raquel, Padrón, José M., García Fernández, José M., Gamarro, Francisco, Ortiz Mellet, Carmen
Publicado 2019

Drug resistance and treatment failure in leishmaniasis: A 21st century challenge

por Ponte-Sucre, Alicia, Gamarro, Francisco, Dujardin, Jean-Claude, Barrett, Michael P., López-Vélez, Rogelio, García-Hernández, Raquel, Pountain, Andrew W., Mwenechanya, Roy, Papadopoulou, Barbara
Publicado 2017

Genomic and transcriptomic alterations in Leishmania donovani lines experimentally resistant to antileishmanial drugs

por Rastrojo, Alberto, García-Hernández, Raquel, Vargas, Paola, Camacho, Esther, Corvo, Laura, Imamura, Hideo, Dujardin, Jean-Claude, Castanys, Santiago, Aguado, Begoña, Gamarro, Francisco, Requena, Jose M.
Publicado 2018

Synthesis of sp(2)-Iminosugar Selenoglycolipids as Multitarget Drug Candidates with Antiproliferative, Leishmanicidal and Anti-Inflammatory Properties

por Sánchez-Fernández, Elena M., García-Hernández, Raquel, Gamarro, Francisco, Arroba, Ana I., Aguilar-Diosdado, Manuel, Padrón, José M., García Fernández, José M., Ortiz Mellet, Carmen
Publicado 2021

Chronic alcohol consumption alters extracellular space geometry and transmitter diffusion in the brain

por De Santis, Silvia, Cosa-Linan, Alejandro, Garcia-Hernandez, Raquel, Dmytrenko, Lesia, Vargova, Lydia, Vorisek, Ivan, Stopponi, Serena, Bach, Patrick, Kirsch, Peter, Kiefer, Falk, Ciccocioppo, Roberto, Sykova, Eva, Moratal, David, Sommer, Wolfgang H., Canals, Santiago
Publicado 2020

Strasseriolides display in vitro and in vivo activity against trypanosomal parasites and cause morphological and size defects in Trypanosoma cruzi

por Bosch-Navarrete, Cristina, Pérez-Moreno, Guiomar, Annang, Frederick, Diaz-Gonzalez, Rosario, García-Hernández, Raquel, Rocha, Hedy, Gamarro, Francisco, Cordón-Obras, Carlos, Navarro, Miguel, Rodriguez, Ana, Genilloud, Olga, Reyes, Fernando, Vicente, Francisca, Ruiz-Pérez, Luis M., González-Pacanowska, Dolores
Publicado 2023

Genomic and Molecular Characterization of Miltefosine Resistance in Leishmania infantum Strains with Either Natural or Acquired Resistance through Experimental Selection of Intrace...

por Mondelaers, Annelies, Sanchez-Cañete, Maria P., Hendrickx, Sarah, Eberhardt, Eline, Garcia-Hernandez, Raquel, Lachaud, Laurence, Cotton, James, Sanders, Mandy, Cuypers, Bart, Imamura, Hideo, Dujardin, Jean-Claude, Delputte, Peter, Cos, Paul, Caljon, Guy, Gamarro, Francisco, Castanys, Santiago, Maes, Louis
Publicado 2016

Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents

por Klug, Dana M., Diaz-Gonzalez, Rosario, Pérez-Moreno, Guiomar, Ceballos-Pérez, Gloria, García-Hernández, Raquel, Gomez-Pérez, Veronica, Ruiz-Pérez, Luis Miguel, Rojas-Barros, Domingo I., Gamarro, Francisco, González-Pacanowska, Dolores, Martínez-Martínez, María S., Manzano, Pilar, Ferrins, Lori, Caffrey, Conor R., Navarro, Miguel, Pollastri, Michael P.
Publicado 2019

Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-b]pyridazines for the Treatment of Human African Trypanosomiasis

por Tear, Westley F., Bag, Seema, Diaz-Gonzalez, Rosario, Ceballos-Pérez, Gloria, Rojas-Barros, Domingo I., Cordon-Obras, Carlos, Pérez-Moreno, Guiomar, García-Hernández, Raquel, Martinez-Martinez, Maria Santos, Ruiz-Perez, Luis Miguel, Gamarro, Francisco, Gonzalez Pacanowska, Dolores, Caffrey, Conor R., Ferrins, Lori, Manzano, Pilar, Navarro, Miguel, Pollastri, Michael P.
Publicado 2019

Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes

por Ferrins, Lori, Buskes, Melissa J., Kapteyn, Madison M., Engels, Hannah N., Enos, Suzanne E., Lu, Chenyang, Klug, Dana M., Singh, Baljinder, Quotadamo, Antonio, Bachovchin, Kelly, Tear, Westley F., Spaulding, Andrew E., Forbes, Katherine C., Bag, Seema, Rivers, Mitch, LeBlanc, Catherine, Burchfield, Erin, Armand, Jeremy R., Diaz-Gonzalez, Rosario, Ceballos-Perez, Gloria, García-Hernández, Raquel, Pérez-Moreno, Guiomar, Bosch-Navarrete, Cristina, Gómez-Liñán, Claudia, Ruiz-Pérez, Luis Miguel, Gamarro, Francisco, González-Pacanowska, Dolores, Navarro, Miguel, Mensa-Wilmot, Kojo, Pollastri, Michael P., Kyle, Dennis E., Rice, Christopher A.
Publicado 2023

Corrigendum: Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes

por Ferrins, Lori, Buskes, Melissa J., Kapteyn, Madison M., Engels, Hannah N., Enos, Suzanne E., Lu, Chenyang, Klug, Dana M., Singh, Baljinder, Quotadamo, Antonio, Bachovchin, Kelly, Tear, Westley F., Spaulding, Andrew E., Forbes, Katherine C., Bag, Seema, Rivers, Mitch, LeBlanc, Catherine, Burchfield, Erin, Armand, Jeremy R., Diaz-Gonzalez, Rosario, Ceballos-Perez, Gloria, García-Hernández, Raquel, Pérez-Moreno, Guiomar, Bosch-Navarrete, Cristina, Gómez-Liñán, Claudia, Ruiz-Pérez, Luis Miguel, Gamarro, Francisco, González-Pacanowska, Dolores, Navarro, Miguel, Mensa-Wilmot, Kojo, Pollastri, Michael P., Kyle, Dennis E., Rice, Christopher A.
Publicado 2023