A new approach to produce [(18)F]MC225 via one-step synthesis, a PET radiotracer for measuring P-gp function

por Garcia-Varela, Lara, Attia, Khaled, Sembrano, John Carlo, Jacquet, Olivier, Antunes, Inês F., Kwizera, Chantal, Visser, Ton J., Dierckx, Rudi A. J. O., Elsinga, Philip H., Luurtsema, Gert
Publicado 2021

In Vivo Induction of P-Glycoprotein Function can be Measured with [(18)F]MC225 and PET

por García-Varela, Lara, Rodríguez-Pérez, Manuel, Custodia, Antía, Moraga-Amaro, Rodrigo, Colabufo, Nicola A., Aguiar, Pablo, Sobrino, Tomás, Dierckx, Rudi A.J.O., van Waarde, Aren, Elsinga, Philip H., Luurtsema, Gert
Publicado 2021

Impact of an Adenosine A(2A) Receptor Agonist and Antagonist on Binding of the Dopamine D(2) Receptor Ligand [(11)C]raclopride in the Rodent Striatum

por Prasad, Kavya, de Vries, Erik F. J., Sijbesma, Jürgen W. A., Garcia-Varela, Lara, Vazquez-Matias, Daniel A., Moraga-Amaro, Rodrigo, Willemsen, Antoon T. M., Dierckx, Rudi A. J. O., van Waarde, Aren
Publicado 2022

Test–Retest Repeatability of [(18)F]MC225-PET in Rodents: A Tracer for Imaging of P-gp Function

por García-Varela, Lara, Vállez García, David, Rodríguez-Pérez, Manuel, van Waarde, Aren, Sijbesma, Jürgen W. A., Schildt, Anna, Kwizera, Chantal, Aguiar, Pablo, Sobrino, Tomás, Dierckx, Rudi A. J. O., Elsinga, Philip H., Luurtsema, Gert
Publicado 2020

Pharmacokinetic Modeling of (R)-[(11)C]verapamil to Measure the P-Glycoprotein Function in Nonhuman Primates

por García-Varela, Lara, García, David Vállez, Kakiuchi, Takeharu, Ohba, Hiroyuki, Nishiyama, Shingo, Tago, Tetsuro, Elsinga, Philip H., Tsukada, Hideo, Colabufo, Nicola A., Dierckx, Rudi A.J.O., van Waarde, Aren, Toyohara, Jun, Boellaard, Ronald, Luurtsema, Gert
Publicado 2020

Pharmacokinetic Modeling of [(18)F]MC225 for Quantification of the P-Glycoprotein Function at the Blood–Brain Barrier in Non-Human Primates with PET

por García-Varela, Lara, Arif, Wejdan M., Vállez García, David, Kakiuchi, Takeharu, Ohba, Hiroyuki, Harada, Norihiro, Tago, Tetsuro, Elsinga, Philip H., Tsukada, Hideo, Colabufo, Nicola Antonio, Dierckx, Rudi A. J. O., van Waarde, Aren, Toyohara, Jun, Boellaard, Ronald, Luurtsema, Gert
Publicado 2020

Head-to-head comparison of (R)-[(11)C]verapamil and [(18)F]MC225 in non-human primates, tracers for measuring P-glycoprotein function

por García-Varela, Lara, Vállez García, David, Aguiar, Pablo, Kakiuchi, Takeharu, Ohba, Hiroyuki, Harada, Norihiro, Nishiyama, Shingo, Tago, Tetsuro, Elsinga, Philip H., Tsukada, Hideo, Colabufo, Nicola A., Dierckx, Rudi A. J. O., van Waarde, Aren, Toyohara, Jun, Boellaard, Ronald, Luurtsema, Gert
Publicado 2021

Evaluation of P-glycoprotein function at the blood–brain barrier using [(18)F]MC225-PET

por Mossel, Pascalle, Garcia Varela, Lara, Arif, Wejdan M., van der Weijden, Chris W. J., Boersma, Hendrikus H., Willemsen, Antoon T. M., Boellaard, Ronald, Elsinga, Philip H., Borra, Ronald J. H., Colabufo, Nicola A., Toyohara, Jun, de Deyn, Peter Paul, Dierckx, Rudi A. J. O., Lammertsma, Adriaan A., Bartels, Anna L., Luurtsema, Gert
Publicado 2021