Silencing of hepatic fate-conversion factors induce tumorigenesis in reprogrammed hepatic progenitor-like cells

por Serrano, Felipe, García-Bravo, Maria, Blazquez, Marina, Torres, Josema, Castell, Jose V., Segovia, Jose C., Bort, Roque
Publicado 2016

Cell Fusion Reprogramming Leads to a Specific Hepatic Expression Pattern during Mouse Bone Marrow Derived Hepatocyte Formation In Vivo

por Quintana-Bustamante, Oscar, Grueso, Esther, Garcia-Escudero, Ramon, Arza, Elvira, Alvarez-Barrientos, Alberto, Fabregat, Isabel, Garcia-Bravo, Maria, Meza, Nestor W., Segovia, Jose C.
Publicado 2012

Efficient and Fast Generation of Relevant Disease Mouse Models by In Vitro and In Vivo Gene Editing of Zygotes

por Sanchez-Baltasar, Raquel, Garcia-Torralba, Aida, Nieto-Romero, Virginia, Page, Angustias, Molinos-Vicente, Andrea, López-Manzaneda, Sergio, Ojeda-Pérez, Isabel, Ramirez, Angel, Navarro, Manuel, Segovia, José Carlos, García-Bravo, María
Publicado 2022

Human Pluripotent Stem Cell-Derived Neurons Are Functionally Mature In Vitro and Integrate into the Mouse Striatum Following Transplantation

por Comella-Bolla, Andrea, Orlandi, Javier G., Miguez, Andrés, Straccia, Marco, García-Bravo, María, Bombau, Georgina, Galofré, Mireia, Sanders, Phil, Carrere, Jordi, Segovia, José Carlos, Blasi, Joan, Allen, Nicholas D., Alberch, Jordi, Soriano, Jordi, Canals, Josep M.
Publicado 2020

Insulin receptor isoform A ameliorates long-term glucose intolerance in diabetic mice

por Diaz-Castroverde, Sabela, Gómez-Hernández, Almudena, Fernández, Silvia, García-Gómez, Gema, Di Scala, Marianna, González-Aseguinolaza, Gloria, Fernández-Millán, Elisa, González-Rodríguez, Águeda, García-Bravo, María, Chambon, Pierre, Álvarez, Carmen, Perdomo, Liliana, Beneit, Nuria, Escribano, Oscar, Benito, Manuel
Publicado 2016

Soluble mutant huntingtin drives early human pathogenesis in Huntington’s disease

por Miguez, Andrés, Gomis, Cinta, Vila, Cristina, Monguió-Tortajada, Marta, Fernández-García, Sara, Bombau, Georgina, Galofré, Mireia, García-Bravo, María, Sanders, Phil, Fernández-Medina, Helena, Poquet, Blanca, Salado-Manzano, Cristina, Roura, Santiago, Alberch, Jordi, Segovia, José Carlos, Allen, Nicholas D., Borràs, Francesc E., Canals, Josep M.
Publicado 2023

Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment

por Navarro, Susana, Quintana-Bustamante, Oscar, Sanchez-Dominguez, Rebeca, Lopez-Manzaneda, Sergio, Ojeda-Perez, Isabel, Garcia-Torralba, Aida, Alberquilla, Omaira, Law, Kenneth, Beard, Brian C., Bastone, Antonella, Rothe, Michael, Villanueva, Mariela, Ramirez, Juan C., Fañanas-Baquero, Sara, Nieto-Romero, Virginia, Molinos-Vicente, Andrea, Gutierrez, Sonia, Nicoletti, Eileen, García-Bravo, María, Bueren, Juan A., Schwartz, Jonathan D., Segovia, Jose-Carlos
Publicado 2021