Genetically Engineered Triple MAPT-Mutant Human-Induced Pluripotent Stem Cells (N279K, P301L, and E10+16 Mutations) Exhibit Impairments in Mitochondrial Bioenergetics and Dynamics

por Szabo, Leonora, Grimm, Amandine, García-León, Juan Antonio, Verfaillie, Catherine M., Eckert, Anne
Publicado 2023

Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer’s Disease

por Garcia-Leon, Juan Antonio, Caceres-Palomo, Laura, Sanchez-Mejias, Elisabeth, Mejias-Ortega, Marina, Nuñez-Diaz, Cristina, Fernandez-Valenzuela, Juan Jose, Sanchez-Varo, Raquel, Davila, Jose Carlos, Vitorica, Javier, Gutierrez, Antonia
Publicado 2020

Distinct disease‐sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patients

por Sanchez‐Mejias, Elisabeth, Nuñez‐Diaz, Cristina, Sanchez‐Varo, Raquel, Gomez‐Arboledas, Angela, Garcia‐Leon, Juan Antonio, Fernandez‐Valenzuela, Juan Jose, Mejias‐Ortega, Marina, Trujillo‐Estrada, Laura, Baglietto‐Vargas, David, Moreno‐Gonzalez, Ines, Davila, Jose Carlos, Vitorica, Javier, Gutierrez, Antonia
Publicado 2019

TRAIL/TRAIL Receptor System and Susceptibility to Multiple Sclerosis

por López-Gómez, Carlos, Fernández, Óscar, García-León, Juan Antonio, Pinto-Medel, María Jesús, Oliver-Martos, Begoña, Ortega-Pinazo, Jesús, Suardíaz, Margarita, García-Trujillo, Lucía, Guijarro-Castro, Cristina, Benito-León, Julián, Prat, Isidro, Varadé, Jezabel, Álvarez-Lafuente, Roberto, Urcelay, Elena, Leyva, Laura
Publicado 2011

Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis

por Sanchez-Varo, Raquel, Mejias-Ortega, Marina, Fernandez-Valenzuela, Juan Jose, Nuñez-Diaz, Cristina, Caceres-Palomo, Laura, Vegas-Gomez, Laura, Sanchez-Mejias, Elisabeth, Trujillo-Estrada, Laura, Garcia-Leon, Juan Antonio, Moreno-Gonzalez, Ines, Vizuete, Marisa, Vitorica, Javier, Baglietto-Vargas, David, Gutierrez, Antonia
Publicado 2022

SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells

por García-León, Juan Antonio, Kumar, Manoj, Boon, Ruben, Chau, David, One, Jennifer, Wolfs, Esther, Eggermont, Kristel, Berckmans, Pieter, Gunhanlar, Nilhan, de Vrij, Femke, Lendemeijer, Bas, Pavie, Benjamin, Corthout, Nikky, Kushner, Steven A., Dávila, José Carlos, Lambrichts, Ivo, Hu, Wei-Shou, Verfaillie, Catherine M.
Publicado 2018

Monocyte-derived cells invade brain parenchyma and amyloid plaques in human Alzheimer’s disease hippocampus

por Muñoz-Castro, Clara, Mejias-Ortega, Marina, Sanchez-Mejias, Elisabeth, Navarro, Victoria, Trujillo-Estrada, Laura, Jimenez, Sebastian, Garcia-Leon, Juan Antonio, Fernandez-Valenzuela, Juan Jose, Sanchez-Mico, Maria Virtudes, Romero-Molina, Carmen, Moreno-Gonzalez, Ines, Baglietto-Vargas, David, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Publicado 2023

Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis

por Alcina, Antonio, Fedetz, Maria, Fernández, Óscar, Saiz, Albert, Izquierdo, Guillermo, Lucas, Miguel, Leyva, Laura, García-León, Juan-Antonio, Abad-Grau, María del Mar, Alloza, Iraide, Antigüedad, Alfredo, Garcia-Barcina, María J, Vandenbroeck, Koen, Varadé, Jezabel, de la Hera, Belén, Arroyo, Rafael, Comabella, Manuel, Montalban, Xavier, Petit-Marty, Natalia, Navarro, Arcadi, Otaegui, David, Olascoaga, Javier, Blanco, Yolanda, Urcelay, Elena, Matesanz, Fuencisla
Publicado 2013

Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer’s disease-like pathology

por Baglietto-Vargas, David, Forner, Stefania, Cai, Lena, Martini, Alessandra C., Trujillo-Estrada, Laura, Swarup, Vivek, Nguyen, Marie Minh Thu, Do Huynh, Kelly, Javonillo, Dominic I., Tran, Kristine Minh, Phan, Jimmy, Jiang, Shan, Kramár, Enikö A., Nuñez-Diaz, Cristina, Balderrama-Gutierrez, Gabriela, Garcia, Franklin, Childs, Jessica, Rodriguez-Ortiz, Carlos J., Garcia-Leon, Juan Antonio, Kitazawa, Masashi, Shahnawaz, Mohammad, Matheos, Dina P., Ma, Xinyi, Da Cunha, Celia, Walls, Ken C., Ager, Rahasson R., Soto, Claudio, Gutierrez, Antonia, Moreno-Gonzalez, Ines, Mortazavi, Ali, Tenner, Andrea J., MacGregor, Grant R., Wood, Marcelo, Green, Kim N., LaFerla, Frank M.
Publicado 2021