Determination of HER2 Amplification Status on Tumour DNA by Digital PCR

por Garcia-Murillas, Isaac, Lambros, Maryou, Turner, Nicholas C.
Publicado 2013

An siRNA screen identifies the GNAS locus as a driver in 20q amplified breast cancer

por Garcia-Murillas, Isaac, Sharpe, Rachel, Pearson, Alex, Campbell, James, Natrajan, Rachael, Ashworth, Alan, Turner, Nicholas C
Publicado 2013

Reproducibility of Digital PCR Assays for Circulating Tumor DNA Analysis in Advanced Breast Cancer

por Hrebien, Sarah, O’Leary, Ben, Beaney, Matthew, Schiavon, Gaia, Fribbens, Charlotte, Bhambra, Amarjit, Johnson, Richard, Garcia-Murillas, Isaac, Turner, Nicholas
Publicado 2016

Relationship of PIK3CA mutation and pathway activity with antiproliferative response to aromatase inhibition

por López-Knowles, Elena, Segal, Corrinne V, Gao, Qiong, Garcia-Murillas, Isaac, Turner, Nicholas C, Smith, Ian, Martin, Lesley-Ann, Dowsett, Mitch
Publicado 2014

Predicting Response to Radical Chemoradiotherapy with Circulating HPV DNA (cHPV-DNA) in Locally Advanced Uterine Cervix Cancer

por Lalondrelle, Susan, Lee, Jen, Cutts, Rosalind J., Garcia Murillas, Isaac, Matthews, Nik, Turner, Nicholas, Harrington, Kevin, Vroobel, Katherine, Moretti, Emily, Bhide, Shreerang A.
Publicado 2023

PIK3CA mutation enrichment and quantitation from blood and tissue

por Keraite, Ieva, Alvarez-Garcia, Virginia, Garcia-Murillas, Isaac, Beaney, Matthew, Turner, Nicholas C., Bartos, Clare, Oikonomidou, Olga, Kersaudy-Kerhoas, Maïwenn, Leslie, Nicholas R.
Publicado 2020

Circulating HPV DNA as a Biomarker for Pre-Invasive and Early Invasive Cervical Cancer: A Feasibility Study

por Bryan, Stacey J., Lee, Jen, Gunu, Richard, Jones, Allison, Olaitan, Adeola, Rosenthal, Adam N., Cutts, Ros J., Garcia-Murillas, Isaac, Turner, Nick, Lalondrelle, Susan, Bhide, Shreerang A.
Publicado 2023

Next Generation Sequencing Assay for Detection of Circulating HPV DNA (cHPV-DNA) in Patients Undergoing Radical (Chemo)Radiotherapy in Anal Squamous Cell Carcinoma (ASCC)

por Lee, Jen Y., Cutts, Rosalind J., White, Ingrid, Augustin, Yolanda, Garcia-Murillas, Isaac, Fenwick, Kerry, Matthews, Nik, Turner, Nicholas C., Harrington, Kevin, Gilbert, Duncan C., Bhide, Shreerang
Publicado 2020

Predicting response to radical (chemo)radiotherapy with circulating HPV DNA in locally advanced head and neck squamous carcinoma

por Lee, Jen Y, Garcia-Murillas, Isaac, Cutts, Rosalind J, De Castro, David Gonzalez, Grove, Lorna, Hurley, Tara, Wang, Fuqiang, Nutting, Christopher, Newbold, Katie, Harrington, Kevin, Turner, Nicholas, Bhide, Shreerang
Publicado 2017

Circulating Tumor DNA Markers for Early Progression on Fulvestrant With or Without Palbociclib in ER+ Advanced Breast Cancer

por O’Leary, Ben, Cutts, Rosalind J, Huang, Xin, Hrebien, Sarah, Liu, Yuan, André, Fabrice, Loibl, Sibylle, Loi, Sherene, Garcia-Murillas, Isaac, Cristofanilli, Massimo, Bartlett, Cynthia Huang, Turner, Nicholas C
Publicado 2020

Molecular characterisation of aromatase inhibitor-resistant advanced breast cancer: the phenotypic effect of ESR1 mutations

por Lopez-Knowles, Elena, Pearson, Alex, Schuster, Gene, Gellert, Pascal, Ribas, Ricardo, Yeo, Belinda, Cutts, Ros, Buus, Richard, Garcia-Murillas, Isaac, Haynes, Ben, Martin, Lesley-Ann, Smith, Ian, Turner, Nick, Dowsett, Mitch
Publicado 2018

Efficient Genotyping of KRAS Mutant Non-Small Cell Lung Cancer Using a Multiplexed Droplet Digital PCR Approach

por Pender, Alexandra, Garcia-Murillas, Isaac, Rana, Sareena, Cutts, Rosalind J., Kelly, Gavin, Fenwick, Kerry, Kozarewa, Iwanka, Gonzalez de Castro, David, Bhosle, Jaishree, O’Brien, Mary, Turner, Nicholas C., Popat, Sanjay, Downward, Julian
Publicado 2015

Early circulating tumor DNA dynamics and clonal selection with palbociclib and fulvestrant for breast cancer

por O’Leary, Ben, Hrebien, Sarah, Morden, James P., Beaney, Matthew, Fribbens, Charlotte, Huang, Xin, Liu, Yuan, Bartlett, Cynthia Huang, Koehler, Maria, Cristofanilli, Massimo, Garcia-Murillas, Isaac, Bliss, Judith M., Turner, Nicholas C.
Publicado 2018

Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels

por Raghu, Padinjat, Coessens, Elise, Manifava, Maria, Georgiev, Plamen, Pettitt, Trevor, Wood, Eleanor, Garcia-Murillas, Isaac, Okkenhaug, Hanneke, Trivedi, Deepti, Zhang, Qifeng, Razzaq, Azam, Zaid, Ola, Wakelam, Michael, O'Kane, Cahir J, Ktistakis, Nicholas
Publicado 2009

Assessing CSF ctDNA to Improve Diagnostic Accuracy and Therapeutic Monitoring in Breast Cancer Leptomeningeal Metastasis

por Fitzpatrick, Amanda, Iravani, Marjan, Mills, Adam, Childs, Lucy, Alaguthurai, Thanussuyah, Clifford, Angela, Garcia-Murillas, Isaac, Van Laere, Steven, Dirix, Luc, Harries, Mark, Okines, Alicia, Turner, Nicholas C., Haider, Syed, Tutt, Andrew N.J., Isacke, Clare M.
Publicado 2022

Baseline Mutations and ctDNA Dynamics as Prognostic and Predictive Factors in ER-Positive/HER2-Negative Metastatic Breast Cancer Patients

por Pascual, Javier, Gil-Gil, Miguel, Proszek, Paula, Zielinski, Christoph, Reay, Alistair, Ruiz-Borrego, Manuel, Cutts, Rosalind, Ciruelos Gil, Eva M., Feber, Andrew, Muñoz-Mateu, Montserrat, Swift, Claire, Bermejo, Begoña, Herranz, Jesus, Margeli Vila, Mireia, Antón, Antonio, Kahan, Zsuzsanna, Csöszi, Tibor, Liu, Yuan, Fernandez-Garcia, Daniel, Garcia-Murillas, Isaac, Hubank, Michael, Turner, Nicholas C., Martín, Miguel
Publicado 2023

Genomic profile of advanced breast cancer in circulating tumour DNA

por Kingston, Belinda, Cutts, Rosalind J., Bye, Hannah, Beaney, Matthew, Walsh-Crestani, Giselle, Hrebien, Sarah, Swift, Claire, Kilburn, Lucy S., Kernaghan, Sarah, Moretti, Laura, Wilkinson, Katie, Wardley, Andrew M., Macpherson, Iain R., Baird, Richard D., Roylance, Rebecca, Reis-Filho, Jorge S., Hubank, Michael, Faull, Iris, Banks, Kimberly C., Lanman, Richard B., Garcia-Murillas, Isaac, Bliss, Judith M., Ring, Alistair, Turner, Nicholas C.
Publicado 2021

Author Correction: Genomic profile of advanced breast cancer in circulating tumor DNA

por Kingston, Belinda, Cutts, Rosalind J., Bye, Hannah, Beaney, Matthew, Walsh-Crestani, Giselle, Hrebien, Sarah, Swift, Claire, Kilburn, Lucy S., Kernaghan, Sarah, Moretti, Laura, Wilkinson, Katie, Wardley, Andrew M., Macpherson, Iain R., Baird, Richard D., Roylance, Rebecca, Reis-Filho, Jorge S., Hubank, Michael, Faull, Iris, Banks, Kimberly C., Lanman, Richard B., Garcia-Murillas, Isaac, Bliss, Judith M., Ring, Alistair, Turner, Nicholas C.
Publicado 2021

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

por Martin, Lesley-Ann, Ribas, Ricardo, Simigdala, Nikiana, Schuster, Eugene, Pancholi, Sunil, Tenev, Tencho, Gellert, Pascal, Buluwela, Laki, Harrod, Alison, Thornhill, Allan, Nikitorowicz-Buniak, Joanna, Bhamra, Amandeep, Turgeon, Marc-Olivier, Poulogiannis, George, Gao, Qiong, Martins, Vera, Hills, Margaret, Garcia-Murillas, Isaac, Fribbens, Charlotte, Patani, Neill, Li, Zheqi, Sikora, Matthew J., Turner, Nicholas, Zwart, Wilbert, Oesterreich, Steffi, Carroll, Jason, Ali, Simak, Dowsett, Mitch
Publicado 2017