Biochemical and structural characterization of C-terminal constructs of bovine soluble guanylate cyclase

por Seeger, Franziska, Garcin, Elsa D
Publicado 2011

Soluble guanylate cyclase crystal clear: 1(st) crystal structure of the wild-type human heterodimeric sGC catalytic domains and implications for activity

por Seeger, Franziska, Garcin, Elsa D
Publicado 2013

From biochemical and structural studies of soluble guanylate cyclase toward drug design

por Laffly, Emmanuelle, Macdonald, Jane, Garcin, Elsa
Publicado 2009

Structural studies of soluble guanylate cyclase

por Macdonald, Jane, Laffly, Emmanuelle, Garcin, Elsa
Publicado 2009

Structure/function of the soluble guanylyl cyclase catalytic domain

por Childers, Kenneth C., Garcin, Elsa D.
Publicado 2018

Regulation of soluble guanylate cyclase by matricellular thrombospondins: implications for blood flow

por Rogers, Natasha M., Seeger, Franziska, Garcin, Elsa D., Roberts, David D., Isenberg, Jeffrey S.
Publicado 2014

Synergistic mutations in soluble guanylyl cyclase (sGC) reveal a key role for interfacial regions in the sGC activation mechanism

por Childers, Kenneth C., Yao, Xin-Qiu, Giannakoulias, Sam, Amason, Joshua, Hamelberg, Donald, Garcin, Elsa D.
Publicado 2019

Giant viruses of the Megavirinae subfamily possess biosynthetic pathways to produce rare bacterial-like sugars in a clade-specific manner

por Notaro, Anna, Poirot, Olivier, Garcin, Elsa D, Nin, Sebastien, Molinaro, Antonio, Tonetti, Michela, De Castro, Cristina, Abergel, Chantal
Publicado 2022

Interfacial Residues Promote an Optimal Alignment of the Catalytic Center in Human Soluble Guanylate Cyclase: Heterodimerization Is Required but Not Sufficient for Activity

por Seeger, Franziska, Quintyn, Royston, Tanimoto, Akiko, Williams, Gareth J., Tainer, John A., Wysocki, Vicki H., Garcin, Elsa D.
Publicado 2014

A fusion of the Bacteroides fragilis ferrous iron import proteins reveals a role for FeoA in stabilizing GTP-bound FeoB

por Sestok, Alex E., Brown, Janae B., Obi, Juliet O., O’Sullivan, Sean M., Garcin, Elsa D., Deredge, Daniel J., Smith, Aaron T.
Publicado 2022

Small-angle X-ray scattering method to characterize molecular interactions: Proof of concept

por Allec, Nicholas, Choi, Mina, Yesupriya, Nikhil, Szychowski, Brian, White, Michael R., Kann, Maricel G., Garcin, Elsa D., Daniel, Marie-Christine, Badano, Aldo
Publicado 2015

Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors

por Miller, Thomas W., Amason, Joshua D., Garcin, Elsa D., Lamy, Laurence, Dranchak, Patricia K., Macarthur, Ryan, Braisted, John, Rubin, Jeffrey S., Burgess, Teresa L., Farrell, Catherine L., Roberts, David D., Inglese, James
Publicado 2019

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase

por Garcin, Elsa D., Arvai, Andrew S., Rosenfeld, Robin J., Kroeger, Matt D., Crane, Brian R., Andersson, Gunilla, Andrews, Glen, Hamley, Peter J., Mallinder, Philip R., Nicholls, David J., St-Gallay, Stephen A., Tinker, Alan C., Gensmantel, Nigel P., Mete, Antonio, Cheshire, David R., Connolly, Stephen, Stuehr, Dennis J., Åberg, Anders, Wallace, Alan V., Tainer, John A., Getzoff, Elizabeth D.
Publicado 2008