DNA polymerases in biotechnology

por Gardner, Andrew F., Kelman, Zvi
Publicado 2014

Editorial: The DNA Replication Machinery as Therapeutic Targets

por Gardner, Andrew F., Kelman, Zvi
Publicado 2019

Pre-steady-state Kinetic Analysis of a Family D DNA Polymerase from Thermococcus sp. 9°N Reveals Mechanisms for Archaeal Genomic Replication and Maintenance

por Schermerhorn, Kelly M., Gardner, Andrew F.
Publicado 2015

The Roles of Family B and D DNA Polymerases in Thermococcus Species 9°N Okazaki Fragment Maturation

por Greenough, Lucia, Kelman, Zvi, Gardner, Andrew F.
Publicado 2015

Biochemical Characterization of a Structure-Specific Resolving Enzyme from Sulfolobus islandicus Rod-Shaped Virus 2

por Gardner, Andrew F., Guan, Chudi, Jack, William E.
Publicado 2011

Characterization of Sulfolobus islandicus rod-shaped virus 2 gp19, a single-strand specific endonuclease

por Gardner, Andrew F., Prangishvili, David, Jack, William E.
Publicado 2011

High-temperature single-molecule kinetic analysis of thermophilic archaeal MCM helicases

por Schermerhorn, Kelly M., Tanner, Nathan, Kelman, Zvi, Gardner, Andrew F.
Publicado 2016

Characterization of Family D DNA polymerase from Thermococcus sp. 9°N

por Greenough, Lucia, Menin, Julie F., Desai, Nirav S., Kelman, Zvi, Gardner, Andrew F.
Publicado 2014

Defining the RNaseH2 enzyme-initiated ribonucleotide excision repair pathway in Archaea

por Heider, Margaret R., Burkhart, Brett W., Santangelo, Thomas J., Gardner, Andrew F.
Publicado 2017

Novel ribonucleotide discrimination in the RNA polymerase-like two-barrel catalytic core of Family D DNA polymerases

por Zatopek, Kelly M, Alpaslan, Ece, Evans, Thomas C, Sauguet, Ludovic, Gardner, Andrew F
Publicado 2020

Complete Genome Sequence of Kluyveromyces lactis Strain GG799, a Common Yeast Host for Heterologous Protein Expression

por Chuzel, Léa, Ganatra, Mehul B., Schermerhorn, Kelly M., Gardner, Andrew F., Anton, Brian P., Taron, Christopher H.
Publicado 2017

Biochemical reconstitution and genetic characterization of the major oxidative damage base excision DNA repair pathway in Thermococcus kodakarensis

por Gehring, Alexandra M., Zatopek, Kelly M., Burkhart, Brett W., Potapov, Vladimir, Santangelo, Thomas J., Gardner, Andrew F.
Publicado 2019

Adapting capillary gel electrophoresis as a sensitive, high-throughput method to accelerate characterization of nucleic acid metabolic enzymes

por Greenough, Lucia, Schermerhorn, Kelly M., Mazzola, Laurie, Bybee, Joanna, Rivizzigno, Danielle, Cantin, Elizabeth, Slatko, Barton E., Gardner, Andrew F.
Publicado 2016

The Hyperthermophilic Restriction-Modification Systems of Thermococcus kodakarensis Protect Genome Integrity

por Zatopek, Kelly M., Burkhart, Brett W., Morgan, Richard D., Gehring, Alexandra M., Scott, Kristin A., Santangelo, Thomas J., Gardner, Andrew F.
Publicado 2021

Rapid incorporation kinetics and improved fidelity of a novel class of 3′-OH unblocked reversible terminators

por Gardner, Andrew F., Wang, Jinchun, Wu, Weidong, Karouby, Jennifer, Li, Hong, Stupi, Brian P., Jack, William E., Hersh, Megan N., Metzker, Michael L.
Publicado 2012

An archaeal Cas3 protein facilitates rapid recovery from DNA damage

por Miezner, Guy, Turgeman-Grott, Israela, Zatopek, Kelly M, Gardner, Andrew F, Reshef, Leah, Choudhary, Deepak K, Alstetter, Martina, Allers, Thorsten, Marchfelder, Anita, Gophna, Uri
Publicado 2023

Extended Archaeal Histone-Based Chromatin Structure Regulates Global Gene Expression in Thermococcus kodakarensis

por Sanders, Travis J., Ullah, Fahad, Gehring, Alexandra M., Burkhart, Brett W., Vickerman, Robert L., Fernando, Sudili, Gardner, Andrew F., Ben-Hur, Asa, Santangelo, Thomas J.
Publicado 2021

Capillary Electrophoresis-Based Functional Genomics Screening to Discover Novel Archaeal DNA Modifying Enzymes

por Zatopek, Kelly M., Fossa, Samantha L., Bilotti, Katharina, Caffrey, Paul J., Chuzel, Léa, Gehring, Alexandra M., Lohman, Gregory J. S., Taron, Christopher H., Gardner, Andrew F.
Publicado 2022

Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme

por Yan, Jiangyu, Beattie, Thomas R., Rojas, Adriana L., Schermerhorn, Kelly, Gristwood, Tamzin, Trinidad, Jonathan C., Albers, Sonja V., Roversi, Pietro, Gardner, Andrew F., Abrescia, Nicola G. A., Bell, Stephen D.
Publicado 2017

Therminator DNA Polymerase: Modified Nucleotides and Unnatural Substrates

por Gardner, Andrew F., Jackson, Kiserian M., Boyle, Madeleine M., Buss, Jackson A., Potapov, Vladimir, Gehring, Alexandra M., Zatopek, Kelly M., Corrêa Jr., Ivan R., Ong, Jennifer L., Jack, William E.
Publicado 2019