Chiral Resolution of the Enantiomers of the Slow-Onset Dopamine Reuptake Inhibitor CTDP-32476 and Their Activities

por Froimowitz, Mark, Taboada, Rosa, Poulos, Zachary J., Rainone, Dominic J., Imler, Gregory H., Gardner, Eliot L., Kelley, Charles J.
Publicado 2023

PM288. Preclinical Evaluation of Neutral Cannabinoid CB1 Receptor Antagonists and Cannabinoid CB1 Receptor Negative Allosteric Modulators for Treating Drug Addiction

por Gardner, Eliot L., Bi, Guo-Hua, Thakur, Ganesh, Makriyannis, Alexandros, Seltzman, Herbert H., He, Xiang-Hu, Xi, Zheng-Xiong
Publicado 2016

Therapeutic potential of PIMSR, a novel CB1 receptor neutral antagonist, for cocaine use disorder: evidence from preclinical research

por Galaj, Ewa, Hempel, Briana, Moore, Allamar, Klein, Benjamin, Bi, Guo-Hua, Gardner, Eliot L., Seltzman, Herbert H., Xi, Zheng-Xiong
Publicado 2022

β-caryophyllene, an FDA-Approved Food Additive, Inhibits Methamphetamine-Taking and Methamphetamine-Seeking Behaviors Possibly via CB2 and Non-CB2 Receptor Mechanisms

por He, Xiang-Hu, Galaj, Ewa, Bi, Guo-Hua, He, Yi, Hempel, Briana, Wang, Yan-Lin, Gardner, Eliot L., Xi, Zheng-Xiong
Publicado 2021

Brain Cannabinoid CB(2) Receptors Modulate Cocaine’s Actions in Mice

por Xi, Zheng-Xiong, Peng, Xiao-Qing, Li, Xia, Song, Rui, Zhang, Haiying, Liu, Qing-Rong, Yang, Hong-Ju, Bi, Guo-Hua, Li, Jie, Gardner, Eliot L.
Publicado 2011

CB1 Receptor Activation on VgluT2-Expressing Glutamatergic Neurons Underlies Δ(9)-Tetrahydrocannabinol (Δ(9)-THC)-Induced Aversive Effects in Mice

por Han, Xiao, He, Yi, Bi, Guo-Hua, Zhang, Hai-Ying, Song, Rui, Liu, Qing-Rong, Egan, Josephine M., Gardner, Eliot L., Li, Jing, Xi, Zheng-Xiong
Publicado 2017

mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism

por Li, Xia, Peng, Xiao-Qing, Jordan, Chloe J., Li, Jie, Bi, Guo-Hua, He, Yi, Yang, Hong-Ju, Zhang, Hai-Ying, Gardner, Eliot L., Xi, Zheng-Xiong
Publicado 2018

Involvement of the ghrelin system in the maintenance and reinstatement of cocaine-motivated behaviors: a role of adrenergic action at peripheral β1 receptors

por You, Zhi-Bing, Galaj, Ewa, Alén, Francisco, Wang, Bin, Bi, Guo-Hua, Moore, Allamar R., Buck, Tristram, Crissman, Madeline, Pari, Sruti, Xi, Zheng-Xiong, Leggio, Lorenzo, Wise, Roy A., Gardner, Eliot L.
Publicado 2021

Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference

por Liu, Qing-Rong, Canseco-Alba, Ana, Zhang, Hai-Ying, Tagliaferro, Patricia, Chung, Monika, Dennis, Eugene, Sanabria, Branden, Schanz, Norman, Escosteguy-Neto, Joao Carlos, Ishiguro, Hiroki, Lin, Zhicheng, Sgro, Susan, Leonard, Claire M., Santos-Junior, Jair Guilherme, Gardner, Eliot L., Egan, Josephine M., Lee, Jeung Woon, Xi, Zheng-Xiong, Onaivi, Emmanuel S.
Publicado 2017