Promise and Progress of an HIV-1 Cure by Adeno-Associated Virus Vector Delivery of Anti-HIV-1 Biologics

por Gardner, Matthew R.
Publicado 2020

Engineering antibody-like inhibitors to prevent and treat HIV-1 infection

por Gardner, Matthew R., Farzan, Michael
Publicado 2017

eCD4-Ig promotes ADCC activity of sera from HIV-1-infected patients

por Davis-Gardner, Meredith E., Gardner, Matthew R., Alfant, Barnett, Farzan, Michael
Publicado 2017

A Bispecific Antibody That Simultaneously Recognizes the V2- and V3-Glycan Epitopes of the HIV-1 Envelope Glycoprotein Is Broader and More Potent than Its Parental Antibodies

por Davis-Gardner, Meredith E., Alfant, Barnett, Weber, Jesse A., Gardner, Matthew R., Farzan, Michael
Publicado 2020

HIV-1 inhibitory properties of eCD4-Igmim2 determined using an Env-mediated membrane fusion assay

por Yang, Edward, Gardner, Matthew R., Zhou, Amber S., Farzan, Michael, Arvin, Ann M., Oliver, Stefan L.
Publicado 2018

Conditional Regulation of Gene Expression by Ligand-Induced Occlusion of a MicroRNA Target Sequence

por Mou, Huihui, Zhong, Guocai, Gardner, Matthew R., Wang, Haimin, Wang, Yi-Wen, Cheng, Dechun, Farzan, Michael
Publicado 2018

A pentameric protein ring with novel architecture is required for herpesviral packaging

por Didychuk, Allison L, Gates, Stephanie N, Gardner, Matthew R, Strong, Lisa M, Martin, Andreas, Glaunsinger, Britt A
Publicado 2021

Diverse pathways of escape from all well-characterized VRC01-class broadly neutralizing HIV-1 antibodies

por Otsuka, Yuka, Schmitt, Kimberly, Quinlan, Brian D., Gardner, Matthew R., Alfant, Barnett, Reich, Adrian, Farzan, Michael, Choe, Hyeryun
Publicado 2018

High concordance of ELISA and neutralization assays allows for the detection of antibodies to individual AAV serotypes

por Gardner, Matthew R., Mendes, Desiree E., Muniz, Claudia P., Martinez-Navio, José M., Fuchs, Sebastian P., Gao, Guangping, Desrosiers, Ronald C.
Publicado 2022

Mayo Clinic VT calculator: A practical tool for accurate wide complex tachycardia differentiation

por Kashou, Anthony H., LoCoco, Sarah, Gardner, Matthew R., Webb, Jocelyn, Jentzer, Jacob C., Noseworthy, Peter A., DeSimone, Christopher V., Deshmukh, Abhishek J., Asirvatham, Samuel J., May, Adam M.
Publicado 2023

A strategy for high antibody expression with low anti-drug antibodies using AAV9 vectors

por Davis-Gardner, Meredith E., Weber, Jesse A., Xie, Jun, Pekrun, Katja, Alexander, Eric A., Weisgrau, Kim L., Furlott, Jessica R., Rakasz, Eva G., Kay, Mark A., Gao, Guangping, Farzan, Michael, Gardner, Matthew R.
Publicado 2023

Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2

por Mou, Huihui, Quinlan, Brian D., Peng, Haiyong, Guo, Yan, Peng, Shoujiao, Zhang, Lizhou, Davis-Gardner, Meredith E., Gardner, Matthew R., Crynen, Gogce, Voo, Zhi Xiang, Bailey, Charles C., Alpert, Michael D., Rader, Christoph, Choe, Hyeryun, Farzan, Michael
Publicado 2020

Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies

por Gardner, Matthew R., Fetzer, Ina, Kattenhorn, Lisa M., Davis-Gardner, Meredith E., Zhou, Amber S., Alfant, Barnett, Weber, Jesse A., Kondur, Hema R., Martinez-Navio, Jose M., Fuchs, Sebastian P., Desrosiers, Ronald C., Gao, Guangping, Lifson, Jeffrey D., Farzan, Michael
Publicado 2019

A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-knob-in-hole-reversed immunoadhesin

por Vamva, Eirini, Ozog, Stosh, Leaman, Daniel P., Yu-Hong Cheng, Rene, Irons, Nicholas J., Ott, Andee, Stoffers, Claire, Khan, Iram, Goebrecht, Geraldine K.E., Gardner, Matthew R., Farzan, Michael, Rawlings, David J., Zwick, Michael B., James, Richard G., Torbett, Bruce E.
Publicado 2023

Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2

por Mou, Huihui, Quinlan, Brian D., Peng, Haiyong, Liu, Guanqun, Guo, Yan, Peng, Shoujiao, Zhang, Lizhou, Davis-Gardner, Meredith E., Gardner, Matthew R., Crynen, Gogce, DeVaux, Lindsey B., Voo, Zhi Xiang, Bailey, Charles C., Alpert, Michael D., Rader, Christoph, Gack, Michaela U., Choe, Hyeryun, Farzan, Michael
Publicado 2021

Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET.

por Lu, Maolin, Ma, Xiaochu, Castillo-Menendez, Luis R., Gorman, Jason, Alsahafi, Nirmin, Ermel, Utz, Terry, Daniel S., Chambers, Michael, Peng, Dongjun, Zhang, Baoshan, Zhou, Tongqing, Reichard, Nick, Wang, Kevin, Grover, Jonathan R., Carman, Brennan P., Gardner, Matthew R., Nikic-Spiegel, Ivana, Sugawara, Akihiro, Arthos, James, Lemke, Edward A., Smith, Amos B., Farzan, Michael, Abrams, Cameron, Munro, James B., McDermott, Adrian B., Finzi, Andrés, Kwong, Peter D., Blanchard, Scott C., Sodroski, Joseph G., Mothes, Walther
Publicado 2019

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

por Gardner, Matthew R., Kattenhorn, Lisa M., Kondur, Hema R., von Schaewen, Markus, Dorfman, Tatyana, Chiang, Jessica J., Haworth, Kevin G., Decker, Julie M., Alpert, Michael D., Bailey, Charles C., Neale, Ernest S., Fellinger, Christoph H., Joshi, Vinita R., Fuchs, Sebastian P., Martinez-Navio, Jose M., Quinlan, Brian D., Yao, Annie Y., Mouquet, Hugo, Gorman, Jason, Zhang, Baoshan, Poignard, Pascal, Nussenzweig, Michel C., Burton, Dennis R., Kwong, Peter D., Piatak, Michael, Lifson, Jeffrey D., Gao, Guangping, Desrosiers, Ronald C., Evans, David T., Hahn, Beatrice H., Ploss, Alexander, Cannon, Paula M., Seaman, Michael S., Farzan, Michael
Publicado 2015