Phase II study of everolimus for recurrent or progressive pediatric ependymoma

por Bowers, Daniel C, Rajaram, Veena, Karajannis, Matthias A, Gardner, Sharon L, Su, Jack Meng-Fen, Baxter, Patricia, Partap, Sonia, Klesse, Laura J
Publicado 2023

RARE-35. PINEOBLASTOMA IN CHILDREN SIX YEARS OF AGE OR LESS: FINAL REPORT OF THE HEAD START I, II AND III EXPERIENCE

por AbdelBaki, Mohamed S, Abu-Arja, Mohammad H, Davidson, Tom B, Fangusaro, Jason R, Stanek, Joseph R, Dunkel, Ira J, Dhall, Girish, Gardner, Sharon L, Finlay, Jonathan L
Publicado 2020

Orbital Rosai-Dorfman disease initially diagnosed as IgG4-related disease: a case report

por Iyengar, Nishanth S., Golub, Danielle, McQuinn, Michelle W., Hill, Travis, Tang, Karen, Gardner, Sharon L., Harter, David H., Sen, Chandranath, Staffenberg, David A., Thomas, Kristen, Elkin, Zachary, Belinsky, Irina, William, Christopher
Publicado 2020

PTCy, abatacept, and a short course of tacrolimus for GVHD prevention after haploidentical transplantation

por Al-Homsi, A. Samer, Cirrone, Frank, Wo, Stephanie, Cole, Kelli, Suarez-Londono, J. Andres, Gardner, Sharon L., Hsu, Jingmei, Stocker, Kelsey, Bruno, Benedetto, Goldberg, Judith D., Levinson, Benjamin A., Abdul-Hay, Maher
Publicado 2023

GCT-66. FINAL REPORT OF THE PROSPECTIVE NEXT/CNS-GCT-4 CONSORTIUM TRIAL (GemPOx FOLLOWED BY MARROW-ABLATIVE CHEMOTHERAPY) IN PATIENTS WITH REFRACTORY/RECURRENT CNS GERM CELL TUMORS

por Shatara, Margaret, Blue, Megan, Stanek, Joseph R, Liu, Allison Y, Osorio, Diana S, AbdelBaki, Mohamed S, Prevedello, Daniel, Puduvalli, Vinay, Giglio, Pierre, Gardner, Sharon, Allen, Jeffrey, Wong, Kenneth E, Dhall, Girish, Finlay, Jonathan L
Publicado 2020

SYST-07 WINDOW-OF-OPPORTUNITY STUDY OF ONC201 IN PEDIATRIC PATIENTS WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) AND THALAMIC GLIOMA

por Odia, Yazmin, Koschmann, Carl, Tarapore, Rohinton, Allen, Jeffrey, Hall, Matthew, Daghistani, Doured, Khatib, Ziad, Aguilera, Dolly, MacDonald, Tobey, de Blank, Peter, McGovern, Susan Lynne, Mueller, Sabine, Kline, Cassie, Vitanza, Nicholas, Allen, Joshua E, Zaky, Wafik, Gardner, Sharon
Publicado 2022

DIPG-52. PHASE I CLINICAL TRIAL OF ONC201 IN PEDIATRIC H3 K27M-MUTANT GLIOMA OR NEWLY DIAGNOSED DIPG

por Gardner, Sharon, Tarapore, Rohinton, Allen, Jeffrey, Zaky, Wafik, Odia, Yazmin, Hall, Matthew, Daghistani, Doured, Khatib, Ziad, Koschmann, Carl, Aguilera, Dolly, MacDonald, Tobey, Fouladi, Maryam, McGovern, Susan, Kline, Cassie, Vitanza, Nicholas, Lu, Guangrong, Merdinger, Krystal, Oster, Wolfgang, Allen, Joshua, Khatua, Soumen
Publicado 2020

Phase I dose escalation and expansion trial of single agent ONC201 in pediatric diffuse midline gliomas following radiotherapy

por Gardner, Sharon L, Tarapore, Rohinton S, Allen, Jeffrey, McGovern, Susan L, Zaky, Wafik, Odia, Yazmin, Daghistani, Doured, Diaz, Zuanel, Hall, Matthew D, Khatib, Ziad, Koschmann, Carl, Cantor, Evan, Kurokawa, Ryo, MacDonald, Tobey J, Aguilera, Dolly, Vitanza, Nicholas A, Mueller, Sabine, Kline, Cassie, Lu, Guangrong, Allen, Joshua E, Khatua, Soumen
Publicado 2022

LGG-52. BINIMETINIB IN CHILDREN WITH PROGRESSIVE OR RECURRENT LOW-GRADE GLIOMA NOT ASSOCIATED WITH NEUROFIBROMATOSIS TYPE 1: INITIAL RESULTS FROM A MULTI-INSTITUTIONAL PHASE II STU...

por Robison, Nathan, Pauly, Jasmine, Malvar, Jemily, Gardner, Sharon, Allen, Jeffrey, MacDonald, Tobey, Aguilera, Dolly, Baxter, Patricia, Bendel, Anne, Kilburn, Lindsay, Leary, Sarah, Bowers, Daniel, Dorris, Kathleen, Gauvain, Karen, Alva, Elizabeth, Cohen, Kenneth, Nazemi, Kellie, Tan, Yi Juin, Margol, Ashley, Dhall, Girish, Rosser, Tena, Davidson, Tom, Plant, Ashley, Ullrich, Nicole, Bandopadhayay, Pratiti, Agar, Nathalie, Ligon, Keith, Sposto, Richard, Wright, Karen, Kieran, Mark
Publicado 2020

EPCT-03. SERIAL PLASMA AND CSF CELL-FREE TUMOR DNA (CF-TDNA) TRACKING IN DIFFUSE MIDLINE GLIOMA PATIENTS UNDERGOING TREATMENT WITH ONC201

por Cantor, Evan, Wierzbicki, Kyle, Tarapore, Rohinton S, Thomas, Chase, Cartaxo, Rodrigo, Yadav, Viveka Nand, Ravindran, Ramya, Bruzek, Amy K, Wadden, Jack, Babilla, Clarissa May, Kawakibi, Abed Rhaman, Ji, Sunjong, Ramos, Johanna, Paul, Alyssa, Wolfe, Ian, Leonard, Marcia, Robertson, Partricia, Franson, Andrea, Mody, Rajen, Garton, Hugh, Odia, Yazmin, Kline, Cassie, Vitanza, Nicholas A, Khatua, Soumen, Mueller, Sabine, Allen, Joshua E, Gardner, Sharon, Koschmann, Carl
Publicado 2021

LTBK-04. LATE BREAKING ABSTRACT: MEK162 (binimetinib) in children with progressive or recurrent low-grade glioma: a multi-institutional phase II and target validation study

por Robison, Nathan, Pauly, Jasmine, Malvar, Jemily, Gardner, Sharon, Allen, Jeffrey, Margol, Ashley, MacDonald, Tobey, Bendel, Anne, Kilburn, Lindsay, Cluster, Andrew, Bowers, Daniel, Dorris, Kathleen, Ullrich, Nicole, De Mola, Rebecca Loret, Alva, Elizabeth, Leary, Sarah, Baxter, Patricia, Khatib, Ziad, Cohen, Kenneth, Davidson, Tom Belle, Plant, Ashley, Bandopadhayay, Pratiti, Stopka, Sylwia, Agar, Nathalie, Wright, Karen, Nelson, Marvin, Chi, Yueh-Yun, Kieran, Mark
Publicado 2022

Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma

por Snuderl, Matija, Kannan, Kasthuri, Pfaff, Elke, Wang, Shiyang, Stafford, James M., Serrano, Jonathan, Heguy, Adriana, Ray, Karina, Faustin, Arline, Aminova, Olga, Dolgalev, Igor, Stapleton, Stacie L., Zagzag, David, Chiriboga, Luis, Gardner, Sharon L., Wisoff, Jeffrey H., Golfinos, John G., Capper, David, Hovestadt, Volker, Rosenblum, Marc K., Placantonakis, Dimitris G., LeBoeuf, Sarah E., Papagiannakopoulos, Thales Y., Chavez, Lukas, Ahsan, Sama, Eberhart, Charles G., Pfister, Stefan M., Jones, David T. W., Karajannis, Matthias A.
Publicado 2018

Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline glioma

por Cantor, Evan, Wierzbicki, Kyle, Tarapore, Rohinton S, Ravi, Karthik, Thomas, Chase, Cartaxo, Rodrigo, Nand Yadav, Viveka, Ravindran, Ramya, Bruzek, Amy K, Wadden, Jack, John, Vishal, May Babila, Clarissa, Cummings, Jessica R, Rahman Kawakibi, Abed, Ji, Sunjong, Ramos, Johanna, Paul, Alyssa, Walling, Dustin, Leonard, Marcia, Robertson, Patricia, Franson, Andrea, Mody, Rajen, Garton, Hugh J L, Venneti, Sriram, Odia, Yazmin, Kline, Cassie, Vitanza, Nicholas A, Khatua, Soumen, Mueller, Sabine, Allen, Joshua E, Gardner, Sharon L, Koschmann, Carl
Publicado 2022

HGG-18. CLINICAL EFFICACY OF ONC201 IN THALAMIC H3 K27M-MUTANT GLIOMA

por Kawakibi, Abed Rahman, Tarapore, Rohinton S, Gardner, Sharon, Chi, Andrew, Kurz, Sylvia, Wen, Patrick Y, Arrillaga-Romany, Isabel, Batchelor, Tracy T, Butowski, Nicholas A, Sumrall, Ashley, Shonka, Nicole, Harrison, Rebecca, DeGroot, John, Mehta, Minesh, Odia, Yazmin, Hall, Matthew D, Daghistani, Doured, Cloughesy, Timothy F, Ellingson, Benjamin M, Umemura, Yoshie, Schwartz, Jonathan, Yadav, Vivekanand, Cartaxo, Rodrigo, Siada, Ruby, Miklja, Zachary, Bruzek, Amy, Cantor, Evan, Wierzbicki, Kyle, Paul, Alyssa, Wolfe, Ian, Leaoard, Marcia, Garton, Hugh, Mody, Rajen, Robertson, Patricia L, Lu, Guangrong, Merdinger, Krystal, Venneti, Sriram, Oster, Wolfgang, Allen, Joshua E, Koschmann, Carl
Publicado 2020

Clinical utility of whole-genome DNA methylation profiling as a primary molecular diagnostic assay for central nervous system tumors—A prospective study and guidelines for clinical...

por Galbraith, Kristyn, Vasudevaraja, Varshini, Serrano, Jonathan, Shen, Guomiao, Tran, Ivy, Abdallat, Nancy, Wen, Mandisa, Patel, Seema, Movahed-Ezazi, Misha, Faustin, Arline, Spino-Keeton, Marissa, Roberts, Leah Geiser, Maloku, Ekrem, Drexler, Steven A, Liechty, Benjamin L, Pisapia, David, Krasnozhen-Ratush, Olga, Rosenblum, Marc, Shroff, Seema, Boué, Daniel R, Davidson, Christian, Mao, Qinwen, Suchi, Mariko, North, Paula, Hopp, Amanda, Segura, Annette, Jarzembowski, Jason A, Parsons, Lauren, Johnson, Mahlon D, Mobley, Bret, Samore, Wesley, McGuone, Declan, Gopal, Pallavi P, Canoll, Peter D, Horbinski, Craig, Fullmer, Joseph M, Farooqi, Midhat S, Gokden, Murat, Wadhwani, Nitin R, Richardson, Timothy E, Umphlett, Melissa, Tsankova, Nadejda M, DeWitt, John C, Sen, Chandra, Placantonakis, Dimitris G, Pacione, Donato, Wisoff, Jeffrey H, Teresa Hidalgo, Eveline, Harter, David, William, Christopher M, Cordova, Christine, Kurz, Sylvia C, Barbaro, Marissa, Orringer, Daniel A, Karajannis, Matthias A, Sulman, Erik P, Gardner, Sharon L, Zagzag, David, Tsirigos, Aristotelis, Allen, Jeffrey C, Golfinos, John G, Snuderl, Matija
Publicado 2023

RARE-17. SURVIVAL BENEFIT FOR INDIVIDUALS WITH CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY SYNDROME AND BRAIN TUMORS WHO UNDERGO SURVEILLANCE PROTOCOL. A REPORT FROM THE INTERNATIONA...

por Ercan, Ayse Bahar, Durno, Carol, Bianchi, Vanessa J, Edwards, Melissa, Aronson, Melyssa, Bouffet, Eric, Al-Battashi, Abeer, Alharbi, Musa, Basel, Donald, Bedgood, Raymond, Bendel, Anne, Blumenthal, Deborah T, Bornhorst, Miriam, Bronsema, Annika, Cairney, Elizabeth, Carroll, Sara, Chamdin, Aghiad, Chiaravalli, Stefano, Constantini, Shlomi, Das, Anirban, Dvir, Rina, Farah, Roula, Foulkes, William, Frenkel, Zehavit, Gardner, Sharon, Ghalibafian, Mithra, Gilpin, Cathy, Goudie, Catherine, Hamid, Syed Ahmer, Hansford, Jordan, Harlos, Craig, Hijiya, Nobuko, Hsu, Saunders, Kamihara, Junne, Knipstein, Jeffrey, Koschmann, Carl, Larouche, Valerie, Lassaletta, Alvaro, Lindhorst, Scott, Ling, Simon, Link, Michael, De Mola, Rebecca Loret, Luiten, Rebecca, Lurye, Michal, Maciaszek, Jamie, Magimairajan, Vanan, Maher, Ossama, Massimino, Maura, Mushtaq, Naureen, Newmark, Monica, Nicholas, Garth, Nichols, Kim, Nicolaides, Theodore, Opocher, Enrico, Osborn, Michael, Oshrine, Benjamin, Pearlman, Rachel, Pettee, Daniel, Rapp, Jan, Rashid, Mohsin, Reddy, Alyssa, Reichman, Lara, Remke, Marc, Robbins, Gabriel, Sabel, Magnus, Samuel, David, Scheers, Isabelle, Sen, Santanu, Stearns, Duncan, Sumerauer, David, Swallow, Carol, Taylor, Leslie, Toledano, Helen, Tomboc, Patrick, Van Damme, An, Winer, Ira, Yalon, Michal, Yen, Lee Yi, Zapotocky, Michal, Azad, Vahid Fallah, Zelcer, Shayna, Ziegler, David, Zimmerman, Stefanie, Tabori, Uri
Publicado 2020

Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

por Venneti, Sriram, Kawakibi, Abed Rahman, Ji, Sunjong, Waszak, Sebastian M., Sweha, Stefan R., Mota, Mateus, Pun, Matthew, Deogharkar, Akash, Chung, Chan, Tarapore, Rohinton S., Ramage, Samuel, Chi, Andrew, Wen, Patrick Y., Arrillaga-Romany, Isabel, Batchelor, Tracy T., Butowski, Nicholas A., Sumrall, Ashley, Shonka, Nicole, Harrison, Rebecca A., de Groot, John, Mehta, Minesh, Hall, Matthew D., Daghistani, Doured, Cloughesy, Timothy F., Ellingson, Benjamin M., Beccaria, Kevin, Varlet, Pascale, Kim, Michelle M., Umemura, Yoshie, Garton, Hugh, Franson, Andrea, Schwartz, Jonathan, Jain, Rajan, Kachman, Maureen, Baum, Heidi, Burant, Charles F., Mottl, Sophie L., Cartaxo, Rodrigo T., John, Vishal, Messinger, Dana, Qin, Tingting, Peterson, Erik, Sajjakulnukit, Peter, Ravi, Karthik, Waugh, Alyssa, Walling, Dustin, Ding, Yujie, Xia, Ziyun, Schwendeman, Anna, Hawes, Debra, Yang, Fusheng, Judkins, Alexander R., Wahl, Daniel, Lyssiotis, Costas A., de la Nava, Daniel, Alonso, Marta M., Eze, Augustine, Spitzer, Jasper, Schmidt, Susanne V., Duchatel, Ryan J., Dun, Matthew D., Cain, Jason E., Jiang, Li, Stopka, Sylwia A., Baquer, Gerard, Regan, Michael S., Filbin, Mariella G., Agar, Nathalie Y.R., Zhao, Lili, Kumar-Sinha, Chandan, Mody, Rajen, Chinnaiyan, Arul, Kurokawa, Ryo, Pratt, Drew, Yadav, Viveka N., Grill, Jacques, Kline, Cassie, Mueller, Sabine, Resnick, Adam, Nazarian, Javad, Allen, Joshua E., Odia, Yazmin, Gardner, Sharon L., Koschmann, Carl
Publicado 2023

Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance

por Durno, Carol, Ercan, Ayse Bahar, Bianchi, Vanessa, Edwards, Melissa, Aronson, Melyssa, Galati, Melissa, Atenafu, Eshetu G., Abebe-Campino, Gadi, Al-Battashi, Abeer, Alharbi, Musa, Azad, Vahid Fallah, Baris, Hagit N., Basel, Donald, Bedgood, Raymond, Bendel, Anne, Ben-Shachar, Shay, Blumenthal, Deborah T., Blundell, Maude, Bornhorst, Miriam, Bronsema, Annika, Cairney, Elizabeth, Rhode, Sara, Caspi, Shani, Chamdin, Aghiad, Chiaravalli, Stefano, Constantini, Shlomi, Crooks, Bruce, Das, Anirban, Dvir, Rina, Farah, Roula, Foulkes, William D., Frenkel, Zehavit, Gallinger, Bailey, Gardner, Sharon, Gass, David, Ghalibafian, Mithra, Gilpin, Catherine, Goldberg, Yael, Goudie, Catherine, Hamid, Syed Ahmer, Hampel, Heather, Hansford, Jordan R., Harlos, Craig, Hijiya, Nobuko, Hsu, Saunders, Kamihara, Junne, Kebudi, Rejin, Knipstein, Jeffrey, Koschmann, Carl, Kratz, Christian, Larouche, Valerie, Lassaletta, Alvaro, Lindhorst, Scott, Ling, Simon C., Link, Michael P., Loret De Mola, Rebecca, Luiten, Rebecca, Lurye, Michal, Maciaszek, Jamie L., MagimairajanIssai, Vanan, Maher, Ossama M., Massimino, Maura, McGee, Rose B., Mushtaq, Naureen, Mason, Gary, Newmark, Monica, Nicholas, Garth, Nichols, Kim E., Nicolaides, Theodore, Opocher, Enrico, Osborn, Michael, Oshrine, Benjamin, Pearlman, Rachel, Pettee, Daniel, Rapp, Jan, Rashid, Mohsin, Reddy, Alyssa, Reichman, Lara, Remke, Marc, Robbins, Gabriel, Roy, Sumita, Sabel, Magnus, Samuel, David, Scheers, Isabelle, Schneider, Kami Wolfe, Sen, Santanu, Stearns, Duncan, Sumerauer, David, Swallow, Carol, Taylor, Leslie, Thomas, Gregory, Toledano, Helen, Tomboc, Patrick, Van Damme, An, Winer, Ira, Yalon, Michal, Yen, Lee Yi, Zapotocky, Michal, Zelcer, Shayna, Ziegler, David S., Zimmermann, Stefanie, Hawkins, Cynthia, Malkin, David, Bouffet, Eric, Villani, Anita, Tabori, Uri
Publicado 2021

The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science

por Lilly, Jena V., Rokita, Jo Lynne, Mason, Jennifer L., Patton, Tatiana, Stefankiewiz, Stephanie, Higgins, David, Trooskin, Gerri, Larouci, Carina A., Arya, Kamnaa, Appert, Elizabeth, Heath, Allison P., Zhu, Yuankun, Brown, Miguel A., Zhang, Bo, Farrow, Bailey K., Robins, Shannon, Morgan, Allison M., Nguyen, Thinh Q., Frenkel, Elizabeth, Lehmann, Kaitlin, Drake, Emily, Sullivan, Catherine, Plisiewicz, Alexa, Coleman, Noel, Patterson, Luke, Koptyra, Mateusz, Helili, Zeinab, Van Kuren, Nicholas, Young, Nathan, Kim, Meen Chul, Friedman, Christopher, Lubneuski, Alex, Blackden, Christopher, Williams, Marti, Baubet, Valerie, Tauhid, Lamiya, Galanaugh, Jamie, Boucher, Katie, Ijaz, Heba, Cole, Kristina A., Choudhari, Namrata, Santi, Mariarita, Moulder, Robert W., Waller, Jonathan, Rife, Whitney, Diskin, Sharon J., Mateos, Marion, Parsons, Donald W., Pollack, Ian F., Goldman, Stewart, Leary, Sarah, Caporalini, Chiara, Buccoliero, Anna Maria, Scagnet, Mirko, Haussler, David, Hanson, Derek, Firestein, Ron, Cain, Jason, Phillips, Joanna J., Gupta, Nalin, Mueller, Sabine, Grant, Gerald, Monje-Deisseroth, Michelle, Partap, Sonia, Greenfield, Jeffrey P., Hashizume, Rintaro, Smith, Amy, Zhu, Shida, Johnston, James M., Fangusaro, Jason R., Miller, Matthew, Wood, Matthew D., Gardner, Sharon, Carter, Claire L., Prolo, Laura M., Pisapia, Jared, Pehlivan, Katherine, Franson, Andrea, Niazi, Toba, Rubin, Josh, Abdelbaki, Mohamed, Ziegler, David S., Lindsay, Holly B., Stucklin, Ana Guerreiro, Gerber, Nicolas, Vaske, Olena M., Quinsey, Carolyn, Rood, Brian R., Nazarian, Javad, Raabe, Eric, Jackson, Eric M., Stapleton, Stacie, Lober, Robert M., Kram, David E., Koschmann, Carl, Storm, Phillip B., Lulla, Rishi R., Prados, Michael, Resnick, Adam C., Waanders, Angela J.
Publicado 2022