Homology Modeling Informs Ligand Discovery for the Glutamine Transporter ASCT2

por Garibsingh, Rachel-Ann A., Otte, Nicholas J., Ndaru, Elias, Colas, Claire, Grewer, Christof, Holst, Jeff, Schlessinger, Avner
Publicado 2018

Novel alanine serine cysteine transporter 2 (ASCT2) inhibitors based on sulfonamide and sulfonic acid ester scaffolds

por Ndaru, Elias, Garibsingh, Rachel-Ann A., Shi, YueYue, Wallace, Evan, Zakrepine, Paul, Wang, Jiali, Schlessinger, Avner, Grewer, Christof
Publicado 2019

Angiomotin stabilization by tankyrase inhibitors antagonizes constitutive TEAD-dependent transcription and proliferation of human tumor cells with Hippo pathway core component muta...

por Troilo, Albino, Benson, Erica K., Esposito, Davide, Garibsingh, Rachel-Ann A., Reddy, E. Premkumar, Mungamuri, Sathish Kumar, Aaronson, Stuart A.
Publicado 2016

Rational design of ASCT2 inhibitors using an integrated experimental-computational approach

por Garibsingh, Rachel-Ann A., Ndaru, Elias, Garaeva, Alisa A., Shi, Yueyue, Zielewicz, Laura, Zakrepine, Paul, Bonomi, Massimiliano, Slotboom, Dirk J., Paulino, Cristina, Grewer, Christof, Schlessinger, Avner
Publicado 2021