Small Extracellular Vesicle Enrichment of a Retrotransposon-Derived Double-Stranded RNA: A Means to Avoid Autoinflammation?

por Barrios, Marilou H., Garnham, Alexandra L., Foers, Andrew D., Cheng-Sim, Lesley, Masters, Seth L., Pang, Ken C.
Publicado 2021

Extracellular Vesicles in Synovial Fluid from Rheumatoid Arthritis Patients Contain miRNAs with Capacity to Modulate Inflammation

por Foers, Andrew D., Garnham, Alexandra L., Chatfield, Simon, Smyth, Gordon K., Cheng, Lesley, Hill, Andrew F., Wicks, Ian P., Pang, Ken C.
Publicado 2021

Successful identification of predictive profiles for infection utilising systems‐level immune analysis: a pilot study in patients with relapsed and refractory multiple myeloma

por Doerflinger, Marcel, Garnham, Alexandra L, Freytag, Saskia, Harrison, Simon J, Prince, H Miles, Quach, Hang, Slavin, Monica A, Pellegrini, Marc, Teh, Benjamin W
Publicado 2021

Integrated systems immunology approach identifies impaired effector T cell memory responses as a feature of progression to severe dengue fever

por Ioannidis, Lisa J., Studniberg, Stephanie I., Eriksson, Emily M., Suwarto, Suhendro, Denis, Dionisius, Liao, Yang, Shi, Wei, Garnham, Alexandra L., Sasmono, R. Tedjo, Hansen, Diana S.
Publicado 2023

Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis

por Potts, Margaret A., Mizutani, Shinsuke, Garnham, Alexandra L., Li Wai Suen, Connie S. N., Kueh, Andrew J., Tai, Lin, Pal, Martin, Strasser, Andreas, Herold, Marco J.
Publicado 2023

Genome-wide analysis reveals no evidence of trans chromosomal regulation of mammalian immune development

por Johanson, Timothy M., Coughlan, Hannah D., Lun, Aaron T. L., Bediaga, Naiara G., Naselli, Gaetano, Garnham, Alexandra L., Harrison, Leonard C., Smyth, Gordon K., Allan, Rhys S.
Publicado 2018

Multi-level remodelling of chromatin underlying activation of human T cells

por Bediaga, Naiara G., Coughlan, Hannah D., Johanson, Timothy M., Garnham, Alexandra L., Naselli, Gaetano, Schröder, Jan, Fearnley, Liam G., Bandala-Sanchez, Esther, Allan, Rhys S., Smyth, Gordon K., Harrison, Leonard C.
Publicado 2021

Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a

por Shields, Benjamin J., Jackson, Jacob T., Metcalf, Donald, Shi, Wei, Huang, Qiutong, Garnham, Alexandra L., Glaser, Stefan P., Beck, Dominik, Pimanda, John E., Bogue, Clifford W., Smyth, Gordon K., Alexander, Warren S., McCormack, Matthew P.
Publicado 2016

Loss of TIP60 (KAT5) abolishes H2AZ lysine 7 acetylation and causes p53, INK4A, and ARF-independent cell cycle arrest

por Wichmann, Johannes, Pitt, Catherine, Eccles, Samantha, Garnham, Alexandra L., Li-Wai-Suen, Connie S. N., May, Rose, Allan, Elizabeth, Wilcox, Stephen, Herold, Marco J., Smyth, Gordon K., Monahan, Brendon J., Thomas, Tim, Voss, Anne K.
Publicado 2022

Combined Treatment with a WNT Inhibitor and the NSAID Sulindac Reduces Colon Adenoma Burden in Mice with Truncated APC

por Faux, Maree C., Weinstock, Janet, Gogos, Sophia, Prato, Emma, Azimpour, Alexander I., O'Keefe, Ryan, Cathcart-King, Yasmin, Garnham, Alexandra L., Ernst, Matthias, Preaudet, Adele, Christie, Michael, Putoczki, Tracy L., Buchert, Michael, Burgess, Antony W.
Publicado 2022

Proinflammatory microenvironment promotes lymphoma progression in mice with high megakaryocyte and TPO levels

por Au, Amanda E., Corbin, Jason, Lebois, Marion, Gangatirkar, Pradnya, Yassinson, Fatme, Hyslop, Stephanie R., Cannon, Ping, Mason, Kylie D., Li-Wai-Suen, Connie S. N., Garnham, Alexandra L., Moujalled, Diane, Cimmino, Luisa, Alexander, Warren S., Josefsson, Emma C.
Publicado 2022

Blood transcriptomics identifies immune signatures indicative of infectious complications in childhood cancer patients with febrile neutropenia

por Haeusler, Gabrielle M, Garnham, Alexandra L, Li‐Wai‐Suen, Connie SN, Clark, Julia E, Babl, Franz E, Allaway, Zoe, Slavin, Monica A, Mechinaud, Francoise, Smyth, Gordon K, Phillips, Bob, Thursky, Karin A, Pellegrini, Marc, Doerflinger, Marcel
Publicado 2022

G-CSF drives autoinflammation in APLAID

por Mulazzani, Elisabeth, Kong, Klara, Aróstegui, Juan I., Ng, Ashley P., Ranathunga, Nishika, Abeysekera, Waruni, Garnham, Alexandra L., Ng, Sze-Ling, Baker, Paul J., Jackson, Jacob T., Lich, John D., Hibbs, Margaret L., Wicks, Ian P., Louis, Cynthia, Masters, Seth L.
Publicado 2023

Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis

por Sidwell, Tom, Liao, Yang, Garnham, Alexandra L., Vasanthakumar, Ajithkumar, Gloury, Renee, Blume, Jonas, Teh, Peggy P., Chisanga, David, Thelemann, Christoph, de Labastida Rivera, Fabian, Engwerda, Christian R., Corcoran, Lynn, Kometani, Kohei, Kurosaki, Tomohiro, Smyth, Gordon K., Shi, Wei, Kallies, Axel
Publicado 2020

A necroptosis-independent function of RIPK3 promotes immune dysfunction and prevents control of chronic LCMV infection

por Preston, Simon P., Allison, Cody C., Schaefer, Jan, Clow, William, Bader, Stefanie M., Collard, Sophie, Forsyth, Wasan O., Clark, Michelle P., Garnham, Alexandra L., Li-Wai-Suen, Connie S. N., Peiris, Thanushi, Teale, Jack, Mackiewicz, Liana, Davidson, Sophia, Doerflinger, Marcel, Pellegrini, Marc
Publicado 2023

Iron homeostasis governs erythroid phenotype in polycythemia vera

por Bennett, Cavan, Jackson, Victoria E., Pettikiriarachchi, Anne, Hayman, Thomas, Schaeper, Ute, Moir-Meyer, Gemma, Fielding, Katherine, Ataide, Ricardo, Clucas, Danielle, Baldi, Andrew, Garnham, Alexandra L., Li-Wai-Suen, Connie S. N., Loughran, Stephen J., Baxter, E. Joanna, Green, Anthony R., Alexander, Warren S., Bahlo, Melanie, Burbury, Kate, Ng, Ashley P., Pasricha, Sant-Rayn
Publicado 2023

MLKL deficiency protects against low-grade, sterile inflammation in aged mice

por Tovey Crutchfield, Emma C., Garnish, Sarah E., Day, Jessica, Anderton, Holly, Chiou, Shene, Hempel, Anne, Hall, Cathrine, Patel, Komal M., Gangatirkar, Pradnya, Martin, Katherine R., Li Wai Suen, Connie S. N., Garnham, Alexandra L., Kueh, Andrew J., Wicks, Ian P., Silke, John, Nachbur, Ueli, Samson, Andre L., Murphy, James M., Hildebrand, Joanne M.
Publicado 2023

Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy

por Thijssen, Rachel, Tian, Luyi, Anderson, Mary Ann, Flensburg, Christoffer, Jarratt, Andrew, Garnham, Alexandra L., Jabbari, Jafar S., Peng, Hongke, Lew, Thomas E., Teh, Charis E., Gouil, Quentin, Georgiou, Angela, Tan, Tania, Djajawi, Tirta M., Tam, Constantine S., Seymour, John F., Blombery, Piers, Gray, Daniel H.D., Majewski, Ian J., Ritchie, Matthew E., Roberts, Andrew W., Huang, David C.S.
Publicado 2022

Molecular profiling reveals features of clinical immunity and immunosuppression in asymptomatic P. falciparum malaria

por Studniberg, Stephanie I, Ioannidis, Lisa J, Utami, Retno A S, Trianty, Leily, Liao, Yang, Abeysekera, Waruni, Li‐Wai‐Suen, Connie S N, Pietrzak, Halina M, Healer, Julie, Puspitasari, Agatha M, Apriyanti, Dwi, Coutrier, Farah, Poespoprodjo, Jeanne R, Kenangalem, Enny, Andries, Benediktus, Prayoga, Pak, Sariyanti, Novita, Smyth, Gordon K, Cowman, Alan F, Price, Ric N, Noviyanti, Rintis, Shi, Wei, Garnham, Alexandra L, Hansen, Diana S
Publicado 2022

Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection

por Doerflinger, Marcel, Deng, Yexuan, Whitney, Paul, Salvamoser, Ranja, Engel, Sven, Kueh, Andrew J., Tai, Lin, Bachem, Annabell, Gressier, Elise, Geoghegan, Niall D., Wilcox, Stephen, Rogers, Kelly L., Garnham, Alexandra L., Dengler, Michael A., Bader, Stefanie M., Ebert, Gregor, Pearson, Jaclyn S., De Nardo, Dominic, Wang, Nancy, Yang, Chenying, Pereira, Milton, Bryant, Clare E., Strugnell, Richard A., Vince, James E., Pellegrini, Marc, Strasser, Andreas, Bedoui, Sammy, Herold, Marco J.
Publicado 2020