Ku–DNA binding inhibitors modulate the DNA damage response in response to DNA double-strand breaks

por Mendoza-Munoz, Pamela L, Gavande, Navnath S, VanderVere-Carozza, Pamela S, Pawelczak, Katherine S, Dynlacht, Joseph R, Garrett, Joy E, Turchi, John J
Publicado 2023

Characterization and initial demonstration of in vivo efficacy of a novel heat-activated metalloenediyne anti-cancer agent

por Garrett, Joy, Metzger, Erin, Dewhirst, Mark W., Pollok, Karen E., Turchi, John J., Le Poole, Isabelle C., Couch, Kira, Lew, Logan, Sinn, Anthony, Zaleski, Jeffrey M., Dynlacht, Joseph R.
Publicado 2022

Discovery and development of novel DNA-PK inhibitors by targeting the unique Ku–DNA interaction

por Gavande, Navnath S, VanderVere-Carozza, Pamela S, Pawelczak, Katherine S, Mendoza-Munoz, Pamela, Vernon, Tyler L, Hanakahi, Leslyn A, Summerlin, Matthew, Dynlacht, Joseph R, Farmer, Annabelle H, Sears, Catherine R, Nasrallah, Nawar Al, Garrett, Joy, Turchi, John J
Publicado 2020

Radiation therapy generates platelet-activating factor agonists

por Sahu, Ravi P., Harrison, Kathleen A., Weyerbacher, Jonathan, Murphy, Robert C., Konger, Raymond L., Garrett, Joy Elizabeth, Chin-Sinex, Helen Jan, Johnston, Michael Edward, Dynlacht, Joseph R., Mendonca, Marc, McMullen, Kevin, Li, Gengxin, Spandau, Dan F., Travers, Jeffrey B.
Publicado 2016