Validation of CRISPR targeting for proliferation and cytarabine resistance control genes in the acute myeloid leukemia cell line MOLM-13

por Prajapati, Subhash C, Dunham, Nicholas, Fan, Hao, Garrett-Bakelman, Francine E
Publicado 2022

COCOA: coordinate covariation analysis of epigenetic heterogeneity

por Lawson, John T., Smith, Jason P., Bekiranov, Stefan, Garrett-Bakelman, Francine E., Sheffield, Nathan C.
Publicado 2020

methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles

por Akalin, Altuna, Kormaksson, Matthias, Li, Sheng, Garrett-Bakelman, Francine E, Figueroa, Maria E, Melnick, Ari, Mason, Christopher E
Publicado 2012

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution

por Garrett-Bakelman, Francine E., Sheridan, Caroline K., Kacmarczyk, Thadeous J., Ishii, Jennifer, Betel, Doron, Alonso, Alicia, Mason, Christopher E., Figueroa, Maria E., Melnick, Ari M.
Publicado 2015

An optimized algorithm for detecting and annotating regional differential methylation

por Li, Sheng, Garrett-Bakelman, Francine E, Akalin, Altuna, Zumbo, Paul, Levine, Ross, To, Bik L, Lewis, Ian D, Brown, Anna L, D'Andrea, Richard J, Melnick, Ari, Mason, Christopher E
Publicado 2013

Depletion of tet2 results in age-dependent changes in DNA methylation and gene expression in a zebrafish model of myelodysplastic syndrome

por Neelamraju, Yaseswini, Gjini, Evisa, Chhangawala, Sagar, Fan, Hao, He, Shuning, Jing, Chang-Bin, Nguyen, Ashley T., Prajapati, Subhash, Sheridan, Caroline, Houvras, Yariv, Melnick, Ari, Look, A. Thomas, Garrett-Bakelman, Francine E.
Publicado 2023

CD97 is a critical regulator of acute myeloid leukemia stem cell function

por Martin, Gaëlle H., Roy, Nainita, Chakraborty, Sohini, Desrichard, Alexis, Chung, Stephen S., Woolthuis, Carolien M., Hu, Wenhuo, Berezniuk, Iryna, Garrett-Bakelman, Francine E., Hamann, Jörg, Devlin, Sean M., Chan, Timothy A., Park, Christopher Y.
Publicado 2019

Targeted detection and quantitation of histone modifications from 1,000 cells

por Abshiru, Nebiyu A., Sikora, Jacek W., Camarillo, Jeannie M., Morris, Juliette A., Compton, Philip D., Lee, Tak, Neelamraju, Yaseswini, Haddox, Samuel, Sheridan, Caroline, Carroll, Martin, Cripe, Larry D., Tallman, Martin S., Paietta, Elisabeth M., Melnick, Ari M., Thomas, Paul M., Garrett-Bakelman, Francine E., Kelleher, Neil L.
Publicado 2020

Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes

por Paudel, B. Bishal, Tan, Su-Fern, Fox, Todd E., Ung, Johnson, Shaw, Jeremy, Dunton, Wendy, Lee, Irene, Sharma, Arati, Viny, Aaron D., Barth, Brian M., Tallman, Martin S., Cabot, Myles, Garrett-Bakelman, Francine E., Levine, Ross L., Kester, Mark, Claxton, David, Feith, David J., Janes, Kevin A., Loughran, Thomas P.
Publicado 2023

The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 controls myeloid differentiation of normal and leukemia cells

por Vu, Ly P., Pickering, Brian F., Cheng, Yuanming, Zaccara, Sara, Nguyen, Diu, Minuesa, Gerard, Chou, Timothy, Chow, Arthur, Saletore, Yogesh, MacKay, Matthew, Schulman, Jessica, Famulare, Christopher, Patel, Minal, Klimek, Virginia M., Garrett-Bakelman, Francine E., Melnick, Ari, Carroll, Martin, Mason, Christopher E., Jaffrey, Samie R., Kharas, Michael G.
Publicado 2017

DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation

por Batra, Rajbir Nath, Lifshitz, Aviezer, Vidakovic, Ana Tufegdzic, Chin, Suet-Feung, Sati-Batra, Ankita, Sammut, Stephen-John, Provenzano, Elena, Ali, H. Raza, Dariush, Ali, Bruna, Alejandra, Murphy, Leigh, Purushotham, Arnie, Ellis, Ian, Green, Andrew, Garrett-Bakelman, Francine E., Mason, Chris, Melnick, Ari, Aparicio, Samuel A. J. R., Rueda, Oscar M., Tanay, Amos, Caldas, Carlos
Publicado 2021

Correction: Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group’s clinical trial E3999

por Rapaport, Franck, Seier, Kenneth, Neelamraju, Yaseswini, Hassane, Duane, Baslan, Timour, Gildea, Daniel T., Haddox, Samuel, Lee, Tak, Murdock, H. Moses, Sheridan, Caroline, Thurmond, Alexis, Wang, Ling, Carroll, Martin, Cripe, Larry D., Fernandez, Hugo, Mason, Christopher E., Paietta, Elisabeth, Roboz, Gail J., Sun, Zhuoxin, Tallman, Martin S., Zhang, Yanming, Gönen, Mithat, Levine, Ross, Melnick, Ari M., Kleppe, Maria, Garrett-Bakelman, Francine E.
Publicado 2023

Base-Pair Resolution DNA Methylation Sequencing Reveals Profoundly Divergent Epigenetic Landscapes in Acute Myeloid Leukemia

por Akalin, Altuna, Garrett-Bakelman, Francine E., Kormaksson, Matthias, Busuttil, Jennifer, Zhang, Lu, Khrebtukova, Irina, Milne, Thomas A., Huang, Yongsheng, Biswas, Debabrata, Hess, Jay L., Allis, C. David, Roeder, Robert G., Valk, Peter J. M., Löwenberg, Bob, Delwel, Ruud, Fernandez, Hugo F., Paietta, Elisabeth, Tallman, Martin S., Schroth, Gary P., Mason, Christopher E., Melnick, Ari, Figueroa, Maria E.
Publicado 2012

An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions

por Sevilla, Ana, Papatsenko, Dimitri, Mazloom, Amin R., Xu, Huilei, Vasileva, Ana, Unwin, Richard D., LeRoy, Gary, Chen, Edward Y., Garrett-Bakelman, Francine E., Lee, Dung-Fang, Trinite, Benjamin, Webb, Ryan L., Wang, Zichen, Su, Jie, Gingold, Julian, Melnick, Ari, Garcia, Benjamin A., Whetton, Anthony D., MacArthur, Ben D., Ma’ayan, Avi, Lemischka, Ihor R.
Publicado 2021

Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia

por Rapaport, Franck, Neelamraju, Yaseswini, Baslan, Timour, Hassane, Duane, Gruszczynska, Agata, Robert de Massy, Marc, Farnoud, Noushin, Haddox, Samuel, Lee, Tak, Medina-Martinez, Juan, Sheridan, Caroline, Thurmond, Alexis, Becker, Michael, Bekiranov, Stefan, Carroll, Martin, Moses Murdock, Heardly, Valk, Peter J. M., Bullinger, Lars, D’Andrea, Richard, Lowe, Scott W., Neuberg, Donna, Levine, Ross L., Melnick, Ari, Garrett-Bakelman, Francine E.
Publicado 2021

Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group’s clinical trial E3999

por Rapaport, Franck, Seier, Kenneth, Neelamraju, Yaseswini, Hassane, Duane, Baslan, Timour, Gildea, Daniel T., Haddox, Samuel, Lee, Tak, Murdock, H. Moses, Sheridan, Caroline, Thurmond, Alexis, Wang, Ling, Carroll, Martin, Cripe, Larry D., Fernandez, Hugo, Mason, Christopher E., Paietta, Elisabeth, Roboz, Gail J., Sun, Zhuoxin, Tallman, Martin S., Zhang, Yanming, Gönen, Mithat, Levine, Ross, Melnick, Ari M., Kleppe, Maria, Garrett-Bakelman, Francine E.
Publicado 2022

Dnmt3a Regulates Myeloproliferation and Liver-Specific Expansion of Hematopoietic Stem and Progenitor Cells

por Guryanova, Olga A., Lieu, Yen K., Garrett-Bakelman, Francine E., Spitzer, Barbara, Glass, Jacob L., Shank, Kaitlyn, Valencia Martinez, Ana Belen, Rivera, Sharon A., Durham, Benjamin H., Rapaport, Franck, Keller, Matthew D., Pandey, Suveg, Bastian, Lennart, Tovbin, Daniel, Weinstein, Abby R., Teruya-Feldstein, Julie, Abdel-Wahab, Omar, Santini, Valeria, Mason, Christopher E., Melnick, Ari M., Mukherjee, Siddhartha, Levine, Ross L.
Publicado 2015

Multi-ancestry epigenome-wide analyses identify methylated sites associated with aortic augmentation index in TOPMed MESA

por Hu, Xiaowei, Logan, Jeongok G., Kwon, Younghoon, Lima, Joao A. C., Jacobs, David R., Duprez, Daniel, Brumback, Lyndia, Taylor, Kent D., Durda, Peter, Johnson, W. Craig, Cornell, Elaine, Guo, Xiuqing, Liu, Yongmei, Tracy, Russell P., Blackwell, Thomas W., Papanicolaou, George, Mitchell, Gary F., Rich, Stephen S., Rotter, Jerome I., Van Den Berg, David J., Chirinos, Julio A., Hughes, Timothy M., Garrett-Bakelman, Francine E., Manichaikul, Ani
Publicado 2023

Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers

por Bezdan, Daniela, Grigorev, Kirill, Meydan, Cem, Pelissier Vatter, Fanny A., Cioffi, Michele, Rao, Varsha, MacKay, Matthew, Nakahira, Kiichi, Burnham, Philip, Afshinnekoo, Ebrahim, Westover, Craig, Butler, Daniel, Mozsary, Chris, Donahoe, Timothy, Foox, Jonathan, Mishra, Tejaswini, Lucotti, Serena, Rana, Brinda K., Melnick, Ari M., Zhang, Haiying, Matei, Irina, Kelsen, David, Yu, Kenneth, Lyden, David C., Taylor, Lynn, Bailey, Susan M., Snyder, Michael P., Garrett-Bakelman, Francine E., Ossowski, Stephan, De Vlaminck, Iwijn, Mason, Christopher E.
Publicado 2020

Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia

por Li, Sheng, Garrett-Bakelman, Francine E., Chung, Stephen S., Sanders, Mathijs A., Hricik, Todd, Rapaport, Franck, Patel, Jay, Dillon, Richard, Vijay, Priyanka, Brown, Anna L., Perl, Alexander E., Cannon, Joy, Bullinger, Lars, Luger, Selina, Becker, Michael, Lewis, Ian D., To, Luen Bik, Delwel, Ruud, Löwenberg, Bob, Döhner, Hartmut, Döhner, Konstanze, Guzman, Monica L., Hassane, Duane C., Roboz, Gail J., Grimwade, David, Valk, Peter J.M., D’Andrea, Richard J., Carroll, Martin, Park, Christopher Y., Neuberg, Donna, Levine, Ross, Melnick, Ari M., Mason, Christopher E.
Publicado 2016