Irinotecan Induces Disease Remission in Xenograft Mouse Models of Pediatric MLL-Rearranged Acute Lymphoblastic Leukemia

por Kerstjens, Mark, Garrido Castro, Patricia, Pinhanços, Sandra S., Schneider, Pauline, Wander, Priscilla, Pieters, Rob, Stam, Ronald W.
Publicado 2021

Identification and characterization of relapse-initiating cells in MLL-rearranged infant ALL by single-cell transcriptomics

por Candelli, Tito, Schneider, Pauline, Garrido Castro, Patricia, Jones, Luke A., Bodewes, Eduard, Rockx-Brouwer, Dedeke, Pieters, Rob, Holstege, Frank C. P., Margaritis, Thanasis, Stam, Ronald W.
Publicado 2021

High-Throughput Drug Library Screening in Primary KMT2A-Rearranged Infant ALL Cells Favors the Identification of Drug Candidates That Activate P53 Signaling

por Wander, Priscilla, Arentsen-Peters, Susan T. C. J. M., Vrenken, Kirsten S., Pinhanҫos, Sandra Mimoso, Koopmans, Bianca, Dolman, M. Emmy M., Jones, Luke, Garrido Castro, Patricia, Schneider, Pauline, Kerstjens, Mark, Molenaar, Jan J., Pieters, Rob, Zwaan, Christian Michel, Stam, Ronald W.
Publicado 2022