Development of SFC-MS Method for Quantification of Eicosanoids Biosynthesized in Primary Human Blood Cells

por Schmidt, Louis, Burmeister, Laura Sophie, Greinacher, Andreas, König, Stefanie, Garscha, Ulrike
Publicado 2022

Discovery of novel, non-acidic mPGES-1 inhibitors by virtual screening with a multistep protocol

por Noha, Stefan M., Fischer, Katrin, Koeberle, Andreas, Garscha, Ulrike, Werz, Oliver, Schuster, Daniela
Publicado 2015

Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A(4) Hydrolase

por Teder, Tarvi, König, Stefanie, Singh, Rajkumar, Samuelsson, Bengt, Werz, Oliver, Garscha, Ulrike, Haeggström, Jesper Z.
Publicado 2023

Platelet-Derived S1P and Its Relevance for the Communication with Immune Cells in Multiple Human Diseases

por Tolksdorf, Céline, Moritz, Eileen, Wolf, Robert, Meyer, Ulrike, Marx, Sascha, Bien-Möller, Sandra, Garscha, Ulrike, Jedlitschky, Gabriele, Rauch, Bernhard H.
Publicado 2022

Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening

por Temml, Veronika, Garscha, Ulrike, Romp, Erik, Schubert, Gregor, Gerstmeier, Jana, Kutil, Zsofia, Matuszczak, Barbara, Waltenberger, Birgit, Stuppner, Hermann, Werz, Oliver, Schuster, Daniela
Publicado 2017

Synthesis and structure–activity relationships for some novel diflapolin derivatives with benzimidazole subunit

por Vieider, Lisa, Zoeller, Eva, Romp, Erik, Schoenthaler, Martin, Hernández-Olmos, Victor, Temml, Veronika, Hasenoehrl, Thomas, Schuster, Daniela, Werz, Oliver, Garscha, Ulrike, Matuszczak, Barbara
Publicado 2022

Identification of 2,4‐Dinitro‐Biphenyl‐Based Compounds as MAPEG Inhibitors

por Di Micco, Simone, Terracciano, Stefania, Pierri, Martina, Cantone, Vincenza, Liening, Stefanie, König, Stefanie, Garscha, Ulrike, Hofstetter, Robert Klaus, Koeberle, Andreas, Werz, Oliver, Bruno, Ines, Bifulco, Giuseppe
Publicado 2022

Synthesis, Biological Evaluation and Structure–Activity Relationships of Diflapolin Analogues as Dual sEH/FLAP Inhibitors

por Vieider, Lisa, Romp, Erik, Temml, Veronika, Fischer, Jana, Kretzer, Christian, Schoenthaler, Martin, Taha, Abdulla, Hernández-Olmos, Victor, Sturm, Sonja, Schuster, Daniela, Werz, Oliver, Garscha, Ulrike, Matuszczak, Barbara
Publicado 2018

Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase

por Garscha, Ulrike, Romp, Erik, Pace, Simona, Rossi, Antonietta, Temml, Veronika, Schuster, Daniela, König, Stefanie, Gerstmeier, Jana, Liening, Stefanie, Werner, Markus, Atze, Heiner, Wittmann, Sandra, Weinigel, Christina, Rummler, Silke, Scriba, Gerhard K., Sautebin, Lidia, Werz, Oliver
Publicado 2017

Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction

por Mayr, Fabian, Möller, Gabriele, Garscha, Ulrike, Fischer, Jana, Rodríguez Castaño, Patricia, Inderbinen, Silvia G., Temml, Veronika, Waltenberger, Birgit, Schwaiger, Stefan, Hartmann, Rolf W., Gege, Christian, Martens, Stefan, Odermatt, Alex, Pandey, Amit V., Werz, Oliver, Adamski, Jerzy, Stuppner, Hermann, Schuster, Daniela
Publicado 2020

Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase

por Pein, Helmut, Ville, Alexia, Pace, Simona, Temml, Veronika, Garscha, Ulrike, Raasch, Martin, Alsabil, Khaled, Viault, Guillaume, Dinh, Chau-Phi, Guilet, David, Troisi, Fabiana, Neukirch, Konstantin, König, Stefanie, Bilancia, Rosella, Waltenberger, Birgit, Stuppner, Hermann, Wallert, Maria, Lorkowski, Stefan, Weinigel, Christina, Rummler, Silke, Birringer, Marc, Roviezzo, Fiorentina, Sautebin, Lidia, Helesbeux, Jean-Jacques, Séraphin, Denis, Mosig, Alexander S., Schuster, Daniela, Rossi, Antonietta, Richomme, Pascal, Werz, Oliver, Koeberle, Andreas
Publicado 2018

Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation

por Neukirch, Konstantin, Alsabil, Khaled, Dinh, Chau-Phi, Bilancia, Rossella, Raasch, Martin, Ville, Alexia, Cerqua, Ida, Viault, Guillaume, Bréard, Dimitri, Pace, Simona, Temml, Veronika, Brunner, Elena, Jordan, Paul M., Marques, Marta C., Loeser, Konstantin, Gollowitzer, André, Permann, Stephan, Gerstmeier, Jana, Lorkowski, Stefan, Stuppner, Hermann, Garscha, Ulrike, Rodrigues, Tiago, Bernardes, Gonçalo J. L., Schuster, Daniela, Séraphin, Denis, Richomme, Pascal, Rossi, Antonietta, Mosig, Alexander S., Roviezzo, Fiorentina, Werz, Oliver, Helesbeux, Jean-Jacques, Koeberle, Andreas
Publicado 2021