Anti-Inflammatory Impact of Minocycline in a Mouse Model of Tauopathy

por Garwood, Claire J., Cooper, Jonathan D., Hanger, Diane P., Noble, Wendy
Publicado 2010

Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer’s disease

por Atherton, Joe, Kurbatskaya, Ksenia, Bondulich, Marie, Croft, Cara L, Garwood, Claire J, Chhabra, Resham, Wray, Selina, Jeromin, Andreas, Hanger, Diane P, Noble, Wendy
Publicado 2014

A Reduced Astrocyte Response to β-Amyloid Plaques in the Ageing Brain Associates with Cognitive Impairment

por Mathur, Ryan, Ince, Paul G., Minett, Thais, Garwood, Claire J., Shaw, Pamela J., Matthews, Fiona E., Brayne, Carol, Simpson, Julie E., Wharton, Stephen B.
Publicado 2015

A neuronal DNA damage response is detected at the earliest stages of Alzheimer's neuropathology and correlates with cognitive impairment in the Medical Research Council's Cognitive...

por Simpson, Julie E., Ince, Paul G., Matthews, Fiona E., Shaw, Pamela J., Heath, Paul R., Brayne, Carol, Garwood, Claire, Higginbottom, Adrian, Wharton, Stephen B.
Publicado 2015

NDRG2 Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain

por Fadul, Motaz M., Garwood, Claire J., Waller, Rachel, Garrett, Navonna, Heath, Paul R., Matthews, Fiona E, Brayne, Carol, Wharton, Stephen B., Simpson, Julie E.
Publicado 2020

Transcriptomic Analysis of Human Astrocytes In Vitro Reveals Hypoxia-Induced Mitochondrial Dysfunction, Modulation of Metabolism, and Dysregulation of the Immune Response

por Allen, Scott P., Seehra, Rajpinder Singh, Heath, Paul R., Hall, Benjamin P. C., Bates, Jessica, Garwood, Claire J., Matuszyk, Martyna M., Wharton, Stephen B., Simpson, Julie E.
Publicado 2020

Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors

por Garwood, Claire J., Ratcliffe, Laura E., Morgan, Sarah V., Simpson, Julie E., Owens, Helen, Vazquez-Villaseñor, Irina, Heath, Paul R., Romero, Ignacio A., Ince, Paul G., Wharton, Stephen B.
Publicado 2015

Loss of IGF1R in Human Astrocytes Alters Complex I Activity and Support for Neurons

por Ratcliffe, Laura E., Vázquez Villaseñor, Irina, Jennings, Luke, Heath, Paul R., Mortiboys, Heather, Schwartzentruber, Aurelie, Karyka, Evangelia, Simpson, Julie E., Ince, Paul G., Garwood, Claire J., Wharton, Stephen B.
Publicado 2018

The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective...

por Fluteau, Adeline, Ince, Paul G., Minett, Thais, Matthews, Fiona E., Brayne, Carol, Garwood, Claire J., Ratcliffe, Laura E., Morgan, Sarah, Heath, Paul R., Shaw, Pamela J., Wharton, Stephen B., Simpson, Julie E.
Publicado 2015

Neuronal DNA damage response‐associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer‐type pathology

por Simpson, Julie E., Ince, Paul G., Minett, Thais, Matthews, Fiona E., Heath, Paul R., Shaw, Pamela J., Goodall, Emily, Garwood, Claire J., Ratcliffe, Laura E., Brayne, Carol, Rattray, Magnus, Wharton, Stephen B.
Publicado 2015

Proteomic and cellular localisation studies suggest non‐tight junction cytoplasmic and nuclear roles for occludin in astrocytes

por Morgan, Sarah V., Garwood, Claire J., Jennings, Luke, Simpson, Julie E., Castelli, Lydia M., Heath, Paul R., Mihaylov, Simeon R., Vaquéz‐Villaseñor, Irina, Minshull, Thomas C., Ince, Paul G., Dickman, Mark J., Hautbergue, Guillaume M., Wharton, Stephen B.
Publicado 2018

The United Kingdom Research study into Ethnicity And COVID-19 outcomes in Healthcare workers (UK-REACH): protocol for a prospective longitudinal cohort study of healthcare and anci...

por Woolf, Katherine, Melbourne, Carl, Bryant, Luke, Guyatt, Anna L, McManus, I Chris, Gupta, Amit, Free, Robert C, Nellums, Laura, Carr, Sue, John, Catherine, Martin, Christopher A, Wain, Louise V, Gray, Laura J, Garwood, Claire, Modhwadia, Vishant, Abrams, Keith R, Tobin, Martin D, Khunti, Kamlesh, Pareek, Manish
Publicado 2021

Cohort Profile: The United Kingdom Research study into Ethnicity and COVID-19 outcomes in Healthcare workers (UK-REACH)

por Bryant, Luke, Free, Robert C, Woolf, Katherine, Melbourne, Carl, Guyatt, Anna L, John, Catherine, Gupta, Amit, Gray, Laura J, Nellums, Laura, Martin, Christopher A, McManus, I Chris, Garwood, Claire, Modhawdia, Vishant, Carr, Sue, Wain, Louise V, Tobin, Martin D, Khunti, Kamlesh, Akubakar, Ibrahim, Pareek, Manish
Publicado 2022

Amyloid binding and beyond: a new approach for Alzheimer's disease drug discovery targeting Aβo–PrP(C) binding and downstream pathways

por Grayson, James D., Baumgartner, Matthew P., Santos Souza, Cleide Dos, Dawes, Samuel J., El Idrissi, Imane Ghafir, Louth, Jennifer C., Stimpson, Sasha, Mead, Emma, Dunbar, Charlotte, Wolak, Joanna, Sharman, Gary, Evans, David, Zhuravleva, Anastasia, Roldan, Margarita Segovia, Colabufo, Nicola Antonio, Ning, Ke, Garwood, Claire, Thomas, James A., Partridge, Benjamin M., de la Vega de Leon, Antonio, Gillet, Valerie J., Rauter, Amélia P., Chen, Beining
Publicado 2021