Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity

por Esposito, Diego, Dudley-Fraser, Jane, Garza-Garcia, Acely, Rittinger, Katrin
Publicado 2022

Solution Structure and Phylogenetics of Prod1, a Member of the Three-Finger Protein Superfamily Implicated in Salamander Limb Regeneration

por Garza-Garcia, Acely, Harris, Richard, Esposito, Diego, Gates, Phillip B., Driscoll, Paul C.
Publicado 2009

Flexible Stoichiometry and Asymmetry of the PIDDosome Core Complex by Heteronuclear NMR Spectroscopy and Mass Spectrometry

por Nematollahi, Lily A., Garza-Garcia, Acely, Bechara, Chérine, Esposito, Diego, Morgner, Nina, Robinson, Carol V., Driscoll, Paul C.
Publicado 2015

Development of a high yield expression and purification system for Domain I of Beta-2-glycoprotein I for the treatment of APS

por McDonnell, Thomas, Pericleous, Charis, Laurine, Emmanuelle, Tommasi, Rita, Garza-Garcia, Acely, Giles, Ian, Ioannou, Yiannis, Rahman, Anisur
Publicado 2015

Expression of a novel mycobacterial phosphodiesterase successfully lowers cAMP levels resulting in reduced tolerance to cell wall–targeting antimicrobials

por Thomson, Michael, Liu, Yi, Nunta, Kanokkan, Cheyne, Ashleigh, Fernandes, Nadia, Williams, Richard, Garza-Garcia, Acely, Larrouy-Maumus, Gerald
Publicado 2022

Flexible nitrogen utilisation by the metabolic generalist pathogen Mycobacterium tuberculosis

por Agapova, Aleksandra, Serafini, Agnese, Petridis, Michael, Hunt, Debbie M, Garza-Garcia, Acely, Sohaskey, Charles D, de Carvalho, Luiz Pedro Sório
Publicado 2019

The tuberculosis necrotizing toxin is an NAD(+) and NADP(+) glycohydrolase with distinct enzymatic properties

por Tak, Uday, Vlach, Jiri, Garza-Garcia, Acely, William, Doreen, Danilchanka, Olga, de Carvalho, Luiz Pedro Sório, Saad, Jamil S., Niederweis, Michael
Publicado 2019

Identification of the orphan gene Prod 1 in basal and other salamander families

por Geng, Jie, Gates, Phillip B, Kumar, Anoop, Guenther, Stefan, Garza-Garcia, Acely, Kuenne, Carsten, Zhang, Peng, Looso, Mario, Brockes, Jeremy P
Publicado 2015

Mechanism of Action of Secreted Newt Anterior Gradient Protein

por Grassme, Kathrin S., Garza-Garcia, Acely, Delgado, Jean-Paul, Godwin, James W., Kumar, Anoop, Gates, Phillip B., Driscoll, Paul C., Brockes, Jeremy P.
Publicado 2016

Evaluating the conformation of recombinant domain I of β(2)-glycoprotein I and its interaction with human monoclonal antibodies

por Pericleous, Charis, Miles, Jennifer, Esposito, Diego, Garza-Garcia, Acely, Driscoll, Paul C., Lambrianides, Anastasia, Latchman, David, Isenberg, David, Rahman, Anisur, Ioannou, Yiannis, Giles, Ian
Publicado 2011

d-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition

por de Chiara, Cesira, Homšak, Miha, Prosser, Gareth A., Douglas, Holly L., Garza-Garcia, Acely, Kelly, Geoff, Purkiss, Andrew G., Tate, Edward W., de Carvalho, Luiz Pedro S.
Publicado 2020

Characterization of Vibrio cholerae Hfq Provides Novel Insights into the Role of the Hfq C-Terminal Region

por Vincent, Helen A., Henderson, Charlotte A., Ragan, Timothy J., Garza-Garcia, Acely, Cary, Peter D., Gowers, Darren M., Malfois, Marc, Driscoll, Paul C., Sobott, Frank, Callaghan, Anastasia J.
Publicado 2012

Uncoupling conformational states from activity in an allosteric enzyme

por Pisco, João P., de Chiara, Cesira, Pacholarz, Kamila J., Garza-Garcia, Acely, Ogrodowicz, Roksana W., Walker, Philip A., Barran, Perdita E., Smerdon, Stephen J., de Carvalho, Luiz Pedro S.
Publicado 2017

Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome

por Pericleous, Charis, Ferreira, Isabel, Borghi, Orietta, Pregnolato, Francesca, McDonnell, Thomas, Garza-Garcia, Acely, Driscoll, Paul, Pierangeli, Silvia, Isenberg, David, Ioannou, Yiannis, Giles, Ian, Meroni, Pier Luigi, Rahman, Anisur
Publicado 2016

An essential bifunctional enzyme in Mycobacterium tuberculosis for itaconate dissimilation and leucine catabolism

por Wang, Hua, Fedorov, Alexander A., Fedorov, Elena V., Hunt, Debbie M., Rodgers, Angela, Douglas, Holly L., Garza-Garcia, Acely, Bonanno, Jeffrey B., Almo, Steven C., de Carvalho, Luiz Pedro Sório
Publicado 2019

Transcriptomic Characterization of Tuberculous Sputum Reveals a Host Warburg Effect and Microbial Cholesterol Catabolism

por Lai, Rachel P. J., Cortes, Teresa, Marais, Suzaan, Rockwood, Neesha, Burke, Melissa L., Garza-Garcia, Acely, Horswell, Stuart, Sesay, Abdul K., O’Garra, Anne, Young, Douglas B., Wilkinson, Robert J.
Publicado 2021

Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β(2)-glycoprotein I in a mouse model of anti-phospholipid antibod...

por Pericleous, Charis, Ruiz-Limón, Patricia, Romay-Penabad, Zurina, Marín, Ana Carrera, Garza-Garcia, Acely, Murfitt, Lucy, Driscoll, Paul C., Latchman, David S., Isenberg, David A., Giles, Ian, Ioannou, Yiannis, Rahman, Anisur, Pierangeli, Silvia S.
Publicado 2015

Functional Characterization of the γ-Aminobutyric Acid Transporter from Mycobacterium smegmatis MC(2) 155 Reveals Sodium-Driven GABA Transport

por Pavić, Ana, Ji, Yurui, Serafini, Agnese, Garza-Garcia, Acely, McPhillie, Martin J., Holmes, Alexandra O. M., de Carvalho, Luiz Pedro Sório, Wang, Yingying, Bartlam, Mark, Goldman, Adrian, Postis, Vincent L. G.
Publicado 2021

Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction

por Jarvis, Ashley, Allerston, Charles K., Jia, Haiyan, Herzog, Birger, Garza-Garcia, Acely, Winfield, Natalie, Ellard, Katie, Aqil, Rehan, Lynch, Rosemary, Chapman, Chris, Hartzoulakis, Basil, Nally, James, Stewart, Mark, Cheng, Lili, Menon, Malini, Tickner, Michelle, Djordjevic, Snezana, Driscoll, Paul C., Zachary, Ian, Selwood, David L.
Publicado 2010

Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism

por Serafini, Agnese, Tan, Lendl, Horswell, Stuart, Howell, Steven, Greenwood, Daniel J., Hunt, Deborah M., Phan, Minh‐Duy, Schembri, Mark, Monteleone, Mercedes, Montague, Christine R., Britton, Warwick, Garza‐Garcia, Acely, Snijders, Ambrosius P., VanderVen, Brian, Gutierrez, Maximiliano G., West, Nicholas P., de Carvalho, Luiz Pedro S.
Publicado 2019