The Role of Protein Kinase Cη in T Cell Biology

por Fu, Guo, Gascoigne, Nicholas R. J.
Publicado 2012

Negative Selection Assay Based on Stimulation of T Cell Receptor Transgenic Thymocytes with Peptide-MHC Tetramers

por Rybakin, Vasily, Gascoigne, Nicholas R. J.
Publicado 2012

Cell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand Recognition

por Brzostek, Joanna, Gascoigne, Nicholas R. J., Rybakin, Vasily
Publicado 2016

The Ups and Downs of Metabolism during the Lifespan of a T Cell

por Balyan, Renu, Gautam, Namrata, Gascoigne, Nicholas R.J.
Publicado 2020

Generation of gene-of-interest double allele knockout clones in primary human T cells by CRISPR

por Wu, Ling, Tan, Jia Chi, Gascoigne, Nicholas R.J.
Publicado 2023

Taming the Sentinels: Microbiome-Derived Metabolites and Polarization of T Cells

por Wojciech, Lukasz, Tan, Kevin S. W., Gascoigne, Nicholas R. J.
Publicado 2020

Initiation of TCR Phosphorylation and Signal Transduction

por Gascoigne, Nicholas R. J., Casas, Javier, Brzostek, Joanna, Rybakin, Vasily
Publicado 2011

T cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation state

por Yachi, Pia P., Lotz, Carina, Ampudia, Jeanette, Gascoigne, Nicholas R.J.
Publicado 2007

Development of a screening strategy for new modulators of T cell receptor signaling and T cell activation

por Chen, Elijah W., Brzostek, Joanna, Gascoigne, Nicholas R. J., Rybakin, Vasily
Publicado 2018

New insights into the interactions between Blastocystis, the gut microbiota, and host immunity

por Deng, Lei, Wojciech, Lukasz, Gascoigne, Nicholas R. J., Peng, Guangneng, Tan, Kevin S. W.
Publicado 2021

A Dual Inhibitor of Cdc7/Cdk9 Potently Suppresses T Cell Activation

por Chen, Elijah W., Tay, Neil Q., Brzostek, Joanna, Gascoigne, Nicholas R. J., Rybakin, Vasily
Publicado 2019

Themis regulates metabolic signaling and effector functions in CD4(+) T cells by controlling NFAT nuclear translocation

por Prasad, Mukul, Brzostek, Joanna, Gautam, Namrata, Balyan, Renu, Rybakin, Vasily, Gascoigne, Nicholas R. J.
Publicado 2020

Single Cell Analysis of Drug Susceptibility of Mycobacterium abscessus during Macrophage Infection

por Brzostek, Joanna, Fatin, Amierah, Chua, Wen Hui, Tan, Hui Yi, Dick, Thomas, Gascoigne, Nicholas R. J.
Publicado 2020

Allelic Exclusion of TCR α-Chains upon Severe Restriction of Vα Repertoire

por Rybakin, Vasily, Westernberg, Luise, Fu, Guo, Kim, Hee-Ok, Ampudia, Jeanette, Sauer, Karsten, Gascoigne, Nicholas R. J.
Publicado 2014

CD40L Expression Allows CD8(+) T Cells to Promote Their Own Expansion and Differentiation through Dendritic Cells

por Tay, Neil Q., Lee, Debbie C. P., Chua, Yen Leong, Prabhu, Nayana, Gascoigne, Nicholas R. J., Kemeny, David M.
Publicado 2017

Non-Stimulatory pMHC Enhance CD8 T Cell Effector Functions by Recruiting Coreceptor-Bound Lck

por Zhao, Xiang, Wu, Liang-Zhe, Ng, Esther K. Y., Leow, Kerisa W. S., Wei, Qianru, Gascoigne, Nicholas R. J., Brzostek, Joanna
Publicado 2021

Lck bound to coreceptor is less active than free Lck

por Wei, Qianru, Brzostek, Joanna, Sankaran, Shvetha, Casas, Javier, Hew, Lois Shi-Qi, Yap, Jiawei, Zhao, Xiang, Wojciech, Lukasz, Gascoigne, Nicholas R. J.
Publicado 2020

Themis-associated phosphatase activity controls signaling in T cell development

por Mehta, Monika, Brzostek, Joanna, Chen, Elijah W., Tung, Desmond W. H., Chen, Shuting, Sankaran, Shvetha, Yap, Jiawei, Rybakin, Vasily, Gascoigne, Nicholas R. J.
Publicado 2018

Expansion of an Unusual Virtual Memory CD8(+) Subpopulation Bearing Vα3.2 TCR in Themis-Deficient Mice

por Prasad, Mukul, Wojciech, Lukasz, Brzostek, Joanna, Hu, Jianfang, Chua, Yen Leong, Tung, Desmond Wai Hon, Yap, Jiawei, Rybakin, Vasily, Gascoigne, Nicholas R. J.
Publicado 2021

In Silico Modeling of Itk Activation Kinetics in Thymocytes Suggests Competing Positive and Negative IP(4) Mediated Feedbacks Increase Robustness

por Mukherjee, Sayak, Rigaud, Stephanie, Seok, Sang-Cheol, Fu, Guo, Prochenka, Agnieszka, Dworkin, Michael, Gascoigne, Nicholas R. J., Vieland, Veronica J., Sauer, Karsten, Das, Jayajit
Publicado 2013