Absorption, Metabolism, and Excretion of [(14)C]-Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) in Healthy Male Subjects

por Gupta, Vipul K., Maier, Gary, Gasink, Leanne, Ek, Amanda, Fudeman, Mary, Srivastava, Praveen, Talley, Angela
Publicado 2023

1120. Absorption, Metabolism, and Excretion of [(14)C]-Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Following a Single Oral Dose in Healthy Male Subjects

por Gupta, Vipul K, Maier, Gary, Gasink, Leanne, Ek, Amanda, Fudeman, Mary, Srivastava, Praveen, Talley, Angela
Publicado 2021

1122. Effect of Aluminum Hydroxide/Magnesium Hydroxide/Simethicone and Omeprazole on the Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) in Healthy Adult Subjects

por Gupta, Vipul K, Patel, Gina, Gasink, Leanne, Bajraktari, Floni, Lei, Yang, Jain, Akash, Srivastava, Praveen, Talley, Angela
Publicado 2021

Effect of an Antacid (Aluminum Hydroxide/Magnesium Hydroxide/Simethicone) or a Proton Pump Inhibitor (Omeprazole) on the Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBP-PI-...

por Patel, Gina, Gupta, Vipul K., Gasink, Leanne, Bajraktari, Floni, Lei, Yang, Jain, Akash, Srivastava, Praveen, Talley, Angela K.
Publicado 2023

2513. CERTAIN-1 Subgroup Analysis: A Phase 3 Study of Cefepime-Taniborbactam Efficacy in the Treatment of Complicated Urinary Tract Infections (cUTI)

por Dorr, Mary Beth, Gasink, Leanne, Henkel, Tim, Moeck, Greg, Chen, Hongzi, McConnell, Scott A, McGovern, Paul
Publicado 2023

Bioequivalence of two oral formulations of tebipenem pivoxil hydrobromide in healthy subjects

por Gupta, Vipul K., Patel, Gina, Gasink, Leanne, Bajraktari, Floni, Lei, Yang, Jain, Akash, Srivastava, Praveen, Talley, Angela K.
Publicado 2022

Genetic Variants and Susceptibility to Neurological Complications Following West Nile Virus Infection

por Loeb, Mark, Eskandarian, Sasha, Rupp, Mark, Fishman, Neil, Gasink, Leanne, Patterson, Jan, Bramson, Jonathan, Hudson, Thomas J, Lemire, Mathieu
Publicado 2011

β-Lactamase Characterization of Gram-Negative Pathogens Recovered from Patients Enrolled in the Phase 2 Trials for Ceftazidime-Avibactam: Clinical Efficacies Analyzed against Subse...

por Mendes, Rodrigo E., Castanheira, Mariana, Gasink, Leanne, Stone, Gregory G., Nichols, Wright W., Flamm, Robert K., Jones, Ronald N.
Publicado 2016

Ceftazidime-avibactam Versus Doripenem for the Treatment of Complicated Urinary Tract Infections, Including Acute Pyelonephritis: RECAPTURE, a Phase 3 Randomized Trial Program

por Wagenlehner, Florian M., Sobel, Jack D., Newell, Paul, Armstrong, Jon, Huang, Xiangning, Stone, Gregory G., Yates, Katrina, Gasink, Leanne B.
Publicado 2016

731. CERTAIN-1: A Phase 3 Study of Cefepime-Taniborbactam Efficacy and Safety in the Treatment of Complicated Urinary Tract Infections (cUTI), including Acute Pyelonephritis (AP)

por McGovern, Paul C, Wagenlehner, Florian, Gasink, Leanne, Moeck, Greg, McLeroth, Patrick L, Beth, Mary, Dane, Aaron, Henkel, Tim
Publicado 2022

2523. Outcomes by Resistance Phenotype and Genotype among Baseline Pathogen in Patients with Complicated Urinary Tract Infection (cUTI) in the Phase 3 CERTAIN-1 Study

por Moeck, Greg, Gasink, Leanne, Dorr, Mary Beth, Chen, Hongzi, Woosley, Leah, Mendes, Rodrigo E, Wagenlehner, Florian, Henkel, Tim, McGovern, Paul
Publicado 2023

Efficacy and Safety of Ceftazidime-Avibactam Plus Metronidazole Versus Meropenem in the Treatment of Complicated Intra-abdominal Infection: Results From a Randomized, Controlled, D...

por Mazuski, John E., Gasink, Leanne B., Armstrong, Jon, Broadhurst, Helen, Stone, Greg G., Rank, Douglas, Llorens, Lily, Newell, Paul, Pachl, Jan
Publicado 2016

2386. Efficacy of Lefamulin (LEF) vs. Moxifloxacin (MOX) Against Common Pathogens in Adults With Community-Acquired Bacterial Pneumonia (CABP): Results From the Phase 3 Lefamulin E...

por File, Thomas, Goldberg, Lisa, Paukner, Susanne, Das, Anita, Gelone, Steven P, Saviski, John, Sweeney, Carolyn, Seltzer, Elyse, Talbot, George H, Gasink, Leanne B
Publicado 2018

Pharmacokinetics of Oral Tebipenem Pivoxil Hydrobromide in Subjects with Various Degrees of Renal Impairment

por Patel, Gina, Rodvold, Keith A., Gupta, Vipul K., Bruss, Jon, Gasink, Leanne, Bajraktari, Floni, Lei, Yang, Jain, Akash, Srivastava, Praveen, Talley, Angela K.
Publicado 2022

LB6. Oral Lefamulin Is Safe and Effective in the Treatment of Adults With Community-Acquired Bacterial Pneumonia (CABP): Results of Lefamulin Evaluation Against Pneumonia (LEAP 2)...

por Alexander, Elizabeth, Goldberg, Lisa, Das, Anita, Moran, Gregory J, Sandrock, Christian, Gasink, Leanne B, Spera, Patricia, Sweeney, Carolyn, Paukner, Susanne, Wicha, Wolfgang W, Schranz, Jennifer
Publicado 2018

Efficacy and Safety of Intravenous-to-oral Lefamulin, a Pleuromutilin Antibiotic, for the Treatment of Community-acquired Bacterial Pneumonia: The Phase III Lefamulin Evaluation Ag...

por File, Thomas M, Goldberg, Lisa, Das, Anita, Sweeney, Carolyn, Saviski, John, Gelone, Steven P, Seltzer, Elyse, Paukner, Susanne, Wicha, Wolfgang W, Talbot, George H, Gasink, Leanne B
Publicado 2019

Erratum to: Efficacy and Safety of Intravenous-to-oral Lefamulin, a Pleuromutilin Antibiotic, for the Treatment of Community-acquired Bacterial Pneumonia: The Phase III Lefamulin E...

por File, Thomas M, Goldberg, Lisa, Das, Anita, Sweeney, Carolyn, Saviski, John, Gelone, Steven P, Seltzer, Elyse, Paukner, Susanne, Wicha, Wolfgang W, Talbot, George H, Gasink, Leanne B
Publicado 2020