Systematic Identification of cis-Regulatory Sequences Active in Mouse and Human Embryonic Stem Cells

por Grskovic, Marica, Chaivorapol, Christina, Gaspar-Maia, Alexandre, Li, Hao, Ramalho-Santos, Miguel
Publicado 2007

High-Efficiency Stem Cell Fusion-Mediated Assay Reveals Sall4 as an Enhancer of Reprogramming

por Wong, Connie C., Gaspar-Maia, Alexandre, Ramalho-Santos, Miguel, Reijo Pera, Renee A.
Publicado 2008

Transcription-associated histone pruning demarcates macroH2A chromatin domains

por Sun, Zhen, Filipescu, Dan, Andrade, Joshua, Gaspar-Maia, Alexandre, Ueberheide, Beatrix, Bernstein, Emily
Publicado 2018

A microfluidic platform for cultivating ovarian cancer spheroids and testing their responses to chemotherapies

por Dadgar, Neda, Gonzalez-Suarez, Alan M., Fattahi, Pouria, Hou, Xiaonan, Weroha, John S., Gaspar-Maia, Alexandre, Stybayeva, Gulnaz, Revzin, Alexander
Publicado 2020

P709: H2AK119UB IN THE TRANSCRIPTIONAL REGULATION OF PATIENTS WITH ASXL1-MUTANT CHRONIC MYELOMONOCYTIC LEUKEMIA

por Binder, Moritz, Wang, Liguo, Safgren, Stephanie, Lee, Jeong-Heon, Lasho, Terra, Finke, Christy, Fernandez, Jenna, Mangaonkar, Abhishek, Gaspar-Maia, Alexandre, Patnaik, Mrinal
Publicado 2023

Clonal Hematopoiesis of Indeterminate Potential Is Associated with Increased Age-Independent Morbidity and Mortality in Patients with COVID-19- the Beyond DNA COVID-19 Project

por Li, Marissa, Lasho, Terra, Binder, Moritz, Mohammed Ismail, Wazim, Geyer, Susan M., Fernandez, Jenna, Kusne, Yael, Mangaonkar, Abhishek A., Kim, Minsuk, Gaspar Maia, Alexandre, Chia, Nicholas, Patnaik, Mrinal M.
Publicado 2021

MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency

por Gaspar-Maia, Alexandre, Qadeer, Zulekha A., Hasson, Dan, Ratnakumar, Kajan, Leu, N. Adrian, Leroy, Gary, Liu, Shichong, Costanzi, Carl, Valle-Garcia, David, Schaniel, Christoph, Lemischka, Ihor, Garcia, Benjamin, Pehrson, John R., Bernstein, Emily
Publicado 2013

Characterization and Optimization of Multiomic Single-Cell Epigenomic Profiling

por Sandoval, Leticia, Mohammed Ismail, Wazim, Mazzone, Amelia, Dumbrava, Mihai, Fernandez, Jenna, Munankarmy, Amik, Lasho, Terra, Binder, Moritz, Simon, Vernadette, Kim, Kwan Hyun, Chia, Nicholas, Lee, Jeong-Heon, Weroha, S. John, Patnaik, Mrinal, Gaspar-Maia, Alexandre
Publicado 2023

Time-restricted feeding prevents deleterious metabolic effects of circadian disruption through epigenetic control of β cell function

por Brown, Matthew R., Sen, Satish K., Mazzone, Amelia, Her, Tracy K., Xiong, Yuning, Lee, Jeong-Heon, Javeed, Naureen, Colwell, Christopher S., Rakshit, Kuntol, LeBrasseur, Nathan K., Gaspar-Maia, Alexandre, Ordog, Tamas, Matveyenko, Aleksey V.
Publicado 2021

Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation

por Fang, Celestia, Wang, Zhenjia, Han, Cuijuan, Safgren, Stephanie L., Helmin, Kathryn A., Adelman, Emmalee R., Serafin, Valentina, Basso, Giuseppe, Eagen, Kyle P., Gaspar-Maia, Alexandre, Figueroa, Maria E., Singer, Benjamin D., Ratan, Aakrosh, Ntziachristos, Panagiotis, Zang, Chongzhi
Publicado 2020

Oncogenic gene expression and epigenetic remodeling of cis-regulatory elements in ASXL1-mutant chronic myelomonocytic leukemia

por Binder, Moritz, Carr, Ryan M., Lasho, Terra L., Finke, Christy M., Mangaonkar, Abhishek A., Pin, Christopher L., Berger, Kurt R., Mazzone, Amelia, Potluri, Sandeep, Ordog, Tamas, Robertson, Keith D., Marks, David L., Fernandez-Zapico, Martin E., Gaspar-Maia, Alexandre, Patnaik, Mrinal M.
Publicado 2022

Glucocorticoids unmask silent non-coding genetic risk variants for common diseases

por Nguyen, Thanh Thanh L, Gao, Huanyao, Liu, Duan, Philips, Trudy Janice, Ye, Zhenqing, Lee, Jeong-Heon, Shi, Geng-xian, Copenhaver, Kaleigh, Zhang, Lingxin, Wei, Lixuan, Yu, Jia, Zhang, Huan, Barath, Abhijeet, Luong, Maggie, Zhang, Cheng, Gaspar-Maia, Alexandre, Li, Hu, Wang, Liewei, Ordog, Tamas, Weinshilboum, Richard M
Publicado 2022

MicroRNA Regulation of Cbx7 Mediates a Switch of Polycomb Orthologs during ESC Differentiation

por O'Loghlen, Ana, Muñoz-Cabello, Ana M., Gaspar-Maia, Alexandre, Wu, Hsan-Au, Banito, Ana, Kunowska, Natalia, Racek, Tomas, Pemberton, Helen N., Beolchi, Patrizia, Lavial, Fabrice, Masui, Osamu, Vermeulen, Michiel, Carroll, Thomas, Graumann, Johannes, Heard, Edith, Dillon, Niall, Azuara, Veronique, Snijders, Ambrosius P., Peters, Gordon, Bernstein, Emily, Gil, Jesus
Publicado 2012

MacroH2A histone variants modulate enhancer activity to repress oncogenic programs and cellular reprogramming

por Mohammed Ismail, Wazim, Mazzone, Amelia, Ghiraldini, Flavia G., Kaur, Jagneet, Bains, Manvir, Munankarmy, Amik, Bagwell, Monique S., Safgren, Stephanie L., Moore-Weiss, John, Buciuc, Marina, Shimp, Lynzie, Leach, Kelsey A., Duarte, Luis F., Nagi, Chandandeep S., Carcamo, Saul, Chung, Chi-Yeh, Hasson, Dan, Dadgar, Neda, Zhong, Jian, Lee, Jeong-Heon, Couch, Fergus J., Revzin, Alexander, Ordog, Tamas, Bernstein, Emily, Gaspar-Maia, Alexandre
Publicado 2023

Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia

por Jin, Qi, Gutierrez Diaz, Blanca, Pieters, Tim, Zhou, Yalu, Narang, Sonali, Fijalkwoski, Igor, Borin, Cristina, Van Laere, Jolien, Payton, Monique, Cho, Byoung-Kyu, Han, Cuijuan, Sun, Limin, Serafin, Valentina, Yacu, George, Von Loocke, Wouter, Basso, Giuseppe, Veltri, Giulia, Dreveny, Ingrid, Ben-Sahra, Issam, Goo, Young Ah, Safgren, Stephanie L., Tsai, Yi-Chien, Bornhauser, Beat, Suraneni, Praveen Kumar, Gaspar-Maia, Alexandre, Kandela, Irawati, Van Vlierberghe, Pieter, Crispino, John D., Tsirigos, Aristotelis, Ntziachristos, Panagiotis
Publicado 2022