Recent Advances in the Development of Nanodelivery Systems Targeting the TRAIL Death Receptor Pathway

por Yagolovich, Anne V., Gasparian, Marine E., Dolgikh, Dmitry A.
Publicado 2023

Combination of TRAIL with Bortezomib Shifted Apoptotic Signaling from DR4 to DR5 Death Receptor by Selective Internalization and Degradation of DR4

por Bychkov, Maxim L., Gasparian, Marine E., Dolgikh, Dmitry A., Kirpichnikov, Mikhail P.
Publicado 2014

Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL

por Artykov, Artem A., Yagolovich, Anne V., Dolgikh, Dmitry A., Kirpichnikov, Mikhail P., Trushina, Daria B., Gasparian, Marine E.
Publicado 2021

Corrigendum: Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL

por Artykov, Artem A., Yagolovich, Anne V., Dolgikh, Dmitry A., Kirpichnikov, Mikhail P., Trushina, Daria B., Gasparian, Marine E.
Publicado 2022

Optimized Heterologous Expression and Efficient Purification of a New TRAIL-Based Antitumor Fusion Protein SRH–DR5-B with Dual VEGFR2 and DR5 Receptor Specificity

por Yagolovich, Anne V., Artykov, Artem A., Isakova, Alina A., Vorontsova, Yekaterina V., Dolgikh, Dmitry A., Kirpichnikov, Mikhail P., Gasparian, Marine E.
Publicado 2022

Chemotherapeutic Agents Sensitize Resistant Cancer Cells to the DR5-Specific Variant DR5-B More Efficiently Than to TRAIL by Modulating the Surface Expression of Death and Decoy Re...

por Artykov, Artem A., Belov, Dmitry A., Shipunova, Victoria O., Trushina, Daria B., Deyev, Sergey M., Dolgikh, Dmitry A., Kirpichnikov, Mikhail P., Gasparian, Marine E.
Publicado 2020

Genetically Modified DR5-Specific TRAIL Variant DR5-B Revealed Dual Antitumor and Protumoral Effect in Colon Cancer Xenografts and an Improved Pharmacokinetic Profile

por Yagolovich, Anne V., Artykov, Artem A., Karmakova, Tatiana A., Vorontsova, Maria S., Pankratov, Andrey A., Andreev-Andrievsky, Alexander A., Dolgikh, Dmitry A., Kirpichnikov, Mikhail P., Gasparian, Marine E.
Publicado 2020

ONC201-Induced Mitochondrial Dysfunction, Senescence-like Phenotype, and Sensitization of Cultured BT474 Human Breast Cancer Cells to TRAIL

por Mishukov, Artem, Odinokova, Irina, Mndlyan, Ekaterina, Kobyakova, Margarita, Abdullaev, Serazhutdin, Zhalimov, Vitaly, Glukhova, Xenia, Galat, Vasiliy, Galat, Yekaterina, Senotov, Anatoly, Fadeev, Roman, Artykov, Artem, Gasparian, Marine E., Solovieva, Marina, Beletsky, Igor, Holmuhamedov, Ekhson
Publicado 2022

DR5-Selective TRAIL Variant DR5-B Functionalized with Tumor-Penetrating iRGD Peptide for Enhanced Antitumor Activity against Glioblastoma

por Yagolovich, Anne V., Isakova, Alina A., Artykov, Artem A., Vorontsova, Yekaterina V., Mazur, Diana V., Antipova, Nadezhda V., Pavlyukov, Marat S., Shakhparonov, Mikhail I., Gileva, Anastasia M., Markvicheva, Elena A., Plotnikova, Ekaterina A., Pankratov, Andrey A., Kirpichnikov, Mikhail P., Gasparian, Marine E., Dolgikh, Dmitry A.
Publicado 2022