Toward a Shigella Vaccine: Opportunities and Challenges to Fight an Antimicrobial-Resistant Pathogen

por Raso, Maria Michelina, Arato, Vanessa, Gasperini, Gianmarco, Micoli, Francesca
Publicado 2023

Dual role of the colonization factor CD2831 in Clostridium difficile pathogenesis

por Arato, Vanessa, Gasperini, Gianmarco, Giusti, Fabiola, Ferlenghi, Ilaria, Scarselli, Maria, Leuzzi, Rosanna
Publicado 2019

Prophylaxis and Treatment against Klebsiella pneumoniae: Current Insights on This Emerging Anti-Microbial Resistant Global Threat

por Arato, Vanessa, Raso, Maria Michelina, Gasperini, Gianmarco, Berlanda Scorza, Francesco, Micoli, Francesca
Publicado 2021

Impact of O-Acetylation on S. flexneri 1b and 2a O-Antigen Immunogenicity in Mice

por Arato, Vanessa, Oldrini, Davide, Massai, Luisa, Gasperini, Gianmarco, Necchi, Francesca, Micoli, Francesca
Publicado 2021

Effect of O-Antigen Chain Length Regulation on the Immunogenicity of Shigella and Salmonella Generalized Modules for Membrane Antigens (GMMA)

por Gasperini, Gianmarco, Raso, Maria Michelina, Arato, Vanessa, Aruta, Maria Grazia, Cescutti, Paola, Necchi, Francesca, Micoli, Francesca
Publicado 2021

Rational Design of a Glycoconjugate Vaccine against Group A Streptococcus

por Di Benedetto, Roberta, Mancini, Francesca, Carducci, Martina, Gasperini, Gianmarco, Moriel, Danilo Gomes, Saul, Allan, Necchi, Francesca, Rappuoli, Rino, Micoli, Francesca
Publicado 2020

Dissecting the contribution of O-Antigen and proteins to the immunogenicity of Shigella sonnei generalized modules for membrane antigens (GMMA)

por Mancini, Francesca, Gasperini, Gianmarco, Rossi, Omar, Aruta, Maria Grazia, Raso, Maria Michelina, Alfini, Renzo, Biagini, Massimiliano, Necchi, Francesca, Micoli, Francesca
Publicado 2021

Outer Membrane Vesicles (OMV)-based and Proteomics-driven Antigen Selection Identifies Novel Factors Contributing to Bordetella pertussis Adhesion to Epithelial Cells

por Gasperini, Gianmarco, Biagini, Massimiliano, Arato, Vanessa, Gianfaldoni, Claudia, Vadi, Alessandro, Norais, Nathalie, Bensi, Giuliano, Delany, Isabel, Pizza, Mariagrazia, Aricò, Beatrice, Leuzzi, Rosanna
Publicado 2018

Rapid generation of Shigella flexneri GMMA displaying natural or new and cross-reactive O-Antigens

por Gasperini, Gianmarco, Raso, Maria Michelina, Schiavo, Fabiola, Aruta, Maria Grazia, Ravenscroft, Neil, Bellich, Barbara, Cescutti, Paola, Necchi, Francesca, Rappuoli, Rino, Micoli, Francesca
Publicado 2022

Exploring the Role of GMMA Components in the Immunogenicity of a 4-Valent Vaccine against Shigella

por Mancini, Francesca, Alfini, Renzo, Caradonna, Valentina, Monaci, Valentina, Carducci, Martina, Gasperini, Gianmarco, Piccioli, Diego, Biagini, Massimiliano, Giannelli, Carlo, Rossi, Omar, Pizza, Mariagrazia, Micoli, Francesca
Publicado 2023

GMMA and Glycoconjugate Approaches Compared in Mice for the Development of a Vaccine against Shigella flexneri Serotype 6

por Raso, Maria Michelina, Gasperini, Gianmarco, Alfini, Renzo, Schiavo, Fabiola, Aruta, Maria Grazia, Carducci, Martina, Forgione, Maria Concetta, Martini, Silvia, Cescutti, Paola, Necchi, Francesca, Micoli, Francesca
Publicado 2020

Rationalizing the design of a broad coverage Shigella vaccine based on evaluation of immunological cross-reactivity among S. flexneri serotypes

por Citiulo, Francesco, Necchi, Francesca, Mancini, Francesca, Rossi, Omar, Aruta, Maria Grazia, Gasperini, Gianmarco, Alfini, Renzo, Rondini, Simona, Micoli, Francesca, Rappuoli, Rino, Saul, Allan, Martin, Laura B.
Publicado 2021

GMMA Is a Versatile Platform to Design Effective Multivalent Combination Vaccines

por Micoli, Francesca, Alfini, Renzo, Di Benedetto, Roberta, Necchi, Francesca, Schiavo, Fabiola, Mancini, Francesca, Carducci, Martina, Palmieri, Elena, Balocchi, Cristiana, Gasperini, Gianmarco, Brunelli, Brunella, Costantino, Paolo, Adamo, Roberto, Piccioli, Diego, Saul, Allan
Publicado 2020

Stability of Outer Membrane Vesicles-Based Vaccines, Identifying the Most Appropriate Methods to Detect Changes in Vaccine Potency

por Palmieri, Elena, Arato, Vanessa, Oldrini, Davide, Ricchetti, Beatrice, Aruta, Maria Grazia, Pansegrau, Werner, Marchi, Sara, Giusti, Fabiola, Ferlenghi, Ilaria, Rossi, Omar, Alfini, Renzo, Giannelli, Carlo, Gasperini, Gianmarco, Necchi, Francesca, Micoli, Francesca
Publicado 2021

Generalized Modules for Membrane Antigens as Carrier for Polysaccharides: Impact of Sugar Length, Density, and Attachment Site on the Immune Response Elicited in Animal Models

por Micoli, Francesca, Alfini, Renzo, Di Benedetto, Roberta, Necchi, Francesca, Schiavo, Fabiola, Mancini, Francesca, Carducci, Martina, Oldrini, Davide, Pitirollo, Olimpia, Gasperini, Gianmarco, Balocchi, Cristiana, Bechi, Nicoletta, Brunelli, Brunella, Piccioli, Diego, Adamo, Roberto
Publicado 2021

GMMA as an Alternative Carrier for a Glycoconjugate Vaccine against Group A Streptococcus

por Palmieri, Elena, Kis, Zoltán, Ozanne, James, Di Benedetto, Roberta, Ricchetti, Beatrice, Massai, Luisa, Carducci, Martina, Oldrini, Davide, Gasperini, Gianmarco, Aruta, Maria Grazia, Rossi, Omar, Kontoravdi, Cleo, Shah, Nilay, Mawas, Fatme, Micoli, Francesca
Publicado 2022

Neisserial Heparin Binding Antigen (NHBA) Contributes to the Adhesion of Neisseria meningitidis to Human Epithelial Cells

por Vacca, Irene, Del Tordello, Elena, Gasperini, Gianmarco, Pezzicoli, Alfredo, Di Fede, Martina, Rossi Paccani, Silvia, Marchi, Sara, Mubaiwa, Tsisti D., Hartley-Tassell, Lauren E., Jennings, Michael P., Seib, Kate L., Masignani, Vega, Pizza, Mariagrazia, Serruto, Davide, Aricò, Beatrice, Delany, Isabel
Publicado 2016

Genetic and Structural Variation in the O-Antigen of Salmonella enterica Serovar Typhimurium Isolates Causing Bloodstream Infections in the Democratic Republic of the Congo

por Van Puyvelde, Sandra, Gasperini, Gianmarco, Biggel, Michael, Phoba, Marie-France, Raso, Maria Michelina, de Block, Tessa, Vanheer, Leen N., Deborggraeve, Stijn, Vandenberg, Olivier, Thomson, Nicholas, Ravenscroft, Neil, Maclennan, Calman A., Bellich, Barbara, Cescutti, Paola, Dougan, Gordon, Jacobs, Jan, Lunguya, Octavie, Micoli, Francesca
Publicado 2022

A next-generation GMMA-based vaccine candidate to fight shigellosis

por Rossi, Omar, Citiulo, Francesco, Giannelli, Carlo, Cappelletti, Emilia, Gasperini, Gianmarco, Mancini, Francesca, Acquaviva, Alessandra, Raso, Maria Michelina, Sollai, Luigi, Alfini, Renzo, Aruta, Maria Grazia, Vitali, Claudia Giorgina, Pizza, Mariagrazia, Necchi, Francesca, Rappuoli, Rino, Martin, Laura B., Berlanda Scorza, Francesco, Colucci, Anna Maria, Micoli, Francesca
Publicado 2023