CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells

por Rupp, Levi J., Schumann, Kathrin, Roybal, Kole T., Gate, Rachel E., Ye, Chun J., Lim, Wendell A., Marson, Alexander
Publicado 2017

Multiplexed droplet single-cell RNA-sequencing using natural genetic variation

por Kang, Hyun Min, Subramaniam, Meena, Targ, Sasha, Nguyen, Michelle, Maliskova, Lenka, McCarthy, Elizabeth, Wan, Eunice, Wong, Simon, Byrnes, Lauren, Lanata, Cristina, Gate, Rachel, Mostafavi, Sara, Marson, Alexander, Zaitlen, Noah, Criswell, Lindsey A, Ye, Chun Jimmie
Publicado 2017

Functional CRISPR dissection of gene networks controlling human regulatory T cell identity

por Schumann, Kathrin, Raju, Siddharth S., Lauber, Michael, Kolb, Saskia, Shifrut, Eric, Cortez, Jessica T., Skartsis, Nikolaos, Nguyen, Vinh Q., Woo, Jonathan M., Roth, Theodore L., Yu, Ruby, Nguyen, Michelle L. T., Simeonov, Dimitre R., Nguyen, David N., Targ, Sasha, Gate, Rachel E., Tang, Qizhi, Bluestone, Jeffrey A., Spitzer, Matthew H., Ye, Chun Jimmie, Marson, Alexander
Publicado 2020

Genetic determinants of co-accessible chromatin regions in activated T cells across humans

por Gate, Rachel E., Cheng, Christine S., Aiden, Aviva P., Siba, Atsede, Tabaka, Marcin, Lituiev, Dmytro, Machol, Ido, Gordon, M. Grace, Subramaniam, Meena, Shamim, Muhammad, Hougen, Kendrick L., Wortman, Ivo, Huang, Su-Chen, Durand, Neva C., Feng, Ting, De Jager, Philip L., Chang, Howard Y., Aiden, Erez Lieberman, Benoist, Christophe, Beer, Michael A., Ye, Chun J., Regev, Aviv
Publicado 2018

Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection

por Ye, Chun Jimmie, Chen, Jenny, Villani, Alexandra-Chloé, Gate, Rachel E., Subramaniam, Meena, Bhangale, Tushar, Lee, Mark N., Raj, Towfique, Raychowdhury, Raktima, Li, Weibo, Rogel, Noga, Simmons, Sean, Imboywa, Selina H., Chipendo, Portia I., McCabe, Cristin, Lee, Michelle H., Frohlich, Irene Y., Stranger, Barbara E., De Jager, Philip L., Regev, Aviv, Behrens, Tim, Hacohen, Nir
Publicado 2018

Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting

por Mavor, David, Barlow, Kyle, Thompson, Samuel, Barad, Benjamin A, Bonny, Alain R, Cario, Clinton L, Gaskins, Garrett, Liu, Zairan, Deming, Laura, Axen, Seth D, Caceres, Elena, Chen, Weilin, Cuesta, Adolfo, Gate, Rachel E, Green, Evan M, Hulce, Kaitlin R, Ji, Weiyue, Kenner, Lillian R, Mensa, Bruk, Morinishi, Leanna S, Moss, Steven M, Mravic, Marco, Muir, Ryan K, Niekamp, Stefan, Nnadi, Chimno I, Palovcak, Eugene, Poss, Erin M, Ross, Tyler D, Salcedo, Eugenia C, See, Stephanie K, Subramaniam, Meena, Wong, Allison W, Li, Jennifer, Thorn, Kurt S, Conchúir, Shane Ó, Roscoe, Benjamin P, Chow, Eric D, DeRisi, Joseph L, Kortemme, Tanja, Bolon, Daniel N, Fraser, James S
Publicado 2016