Treatment Strategies for KRAS-Mutated Non-Small-Cell Lung Cancer

por O’Sullivan, Éabha, Keogh, Anna, Henderson, Brian, Finn, Stephen P., Gray, Steven G., Gately, Kathy
Publicado 2023

Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer

por Cathcart, Mary-Clare, Gately, Kathy, Cummins, Robert, Kay, Elaine, O'Byrne, Kenneth J, Pidgeon, Graham P
Publicado 2011

PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer

por Luszczak, Sabina, Kumar, Christopher, Sathyadevan, Vignesh Krishna, Simpson, Benjamin S., Gately, Kathy A., Whitaker, Hayley C., Heavey, Susan
Publicado 2020

Anti-cancer effects of baicalein in non-small cell lung cancer in-vitro and in-vivo

por Cathcart, Mary-Clare, Useckaite, Zivile, Drakeford, Clive, Semik, Vikki, Lysaght, Joanne, Gately, Kathy, O’Byrne, Kenneth J., Pidgeon, Graham P.
Publicado 2016

In pursuit of synergy: An investigation of the PI3K/mTOR/MEK co-targeted inhibition strategy in NSCLC

por Heavey, Susan, Cuffe, Sinead, Finn, Stephen, Young, Vincent, Ryan, Ronan, Nicholson, Siobhan, Leonard, Niamh, McVeigh, Niall, Barr, Martin, O'Byrne, Kenneth, Gately, Kathy
Publicado 2016

Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response

por Burgess, Joshua T, Bolderson, Emma, Adams, Mark N, Baird, Anne-Marie, Zhang, Shu-Dong, Gately, Kathy A, Umezawa, Kazuo, O'Byrne, Kenneth J, Richard, Derek J
Publicado 2016

Development and characterisation of a panel of phosphatidylinositide 3-kinase – mammalian target of rapamycin inhibitor resistant lung cancer cell lines

por Heavey, Susan, Dowling, Paul, Moore, Gillian, Barr, Martin P., Kelly, Niamh, Maher, Stephen G., Cuffe, Sinead, Finn, Stephen P., O’Byrne, Kenneth J., Gately, Kathy
Publicado 2018

Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer

por Barr, Martin P, Gray, Steven G, Gately, Kathy, Hams, Emily, Fallon, Padraic G, Davies, Anthony Mitchell, Richard, Derek J, Pidgeon, Graham P, O’Byrne, Kenneth J
Publicado 2015

Correction to: Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer

por Barr, Martin P., Gray, Steven G., Gately, Kathy, Hams, Emily, Fallon, Padraic G., Davies, Anthony Mitchell, Richard, Derek J., Pidgeon, Graham P., O’Byrne, Kenneth J.
Publicado 2020

Dasatinib Treatment Increases Sensitivity to c-Met Inhibition in Triple-Negative Breast Cancer Cells

por Gaule, Patricia, Mukherjee, Nupur, Corkery, Brendan, Eustace, Alex J., Gately, Kathy, Roche, Sandra, O’Connor, Robert, O’Byrne, Kenneth J., Walsh, Naomi, Duffy, Michael J., Crown, John, O’Donovan, Norma
Publicado 2019

IHC-based subcellular quantification provides new insights into prognostic relevance of FLIP and procaspase-8 in non-small-cell lung cancer

por Hutchinson, Ryan A, Coleman, Helen G, Gately, Kathy, Young, Vincent, Nicholson, Siobhan, Cummins, Robert, Kay, Elaine, Hynes, Sean O, Dunne, Philip D, Senevirathne, Seedevi, Hamilton, Peter W, McArt, Darragh G, Longley, Daniel B
Publicado 2017

Co-Targeting PIM Kinase and PI3K/mTOR in NSCLC

por Moore, Gillian, Lightner, Clara, Elbai, Samira, Brady, Lauren, Nicholson, Siobhan, Ryan, Ronan, O’Sullivan, Katie E., O’Byrne, Kenneth J., Blanco-Aparicio, Carmen, Cuffe, Sinead, O’Neill, Michael, Heavey, Susan, Finn, Stephen P., Gately, Kathy
Publicado 2021

Protein Tyrosine Phosphatase Non-Receptor 11 (PTPN11/Shp2) as a Driver Oncogene and a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC)

por Richards, Cathy E., Elamin, Yasir Y., Carr, Aoife, Gately, Kathy, Rafee, Shereen, Cremona, Mattia, Hanrahan, Emer, Smyth, Robert, Ryan, Daniel, Morgan, Ross K., Kennedy, Susan, Hudson, Lance, Fay, Joanna, O’Byrne, Kenneth, Hennessy, Bryan T., Toomey, Sinead
Publicado 2023

Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer

por Luszczak, Sabina, Simpson, Benjamin S., Stopka-Farooqui, Urszula, Sathyadevan, Vignesh Krishna, Echeverria, Lina M. Carmona, Kumar, Christopher, Costa, Helena, Haider, Aiman, Freeman, Alex, Jameson, Charles, Ratynska, Marzena, Ben-Salha, Imen, Sridhar, Ashwin, Shaw, Greg, Kelly, John D., Pye, Hayley, Gately, Kathy A., Whitaker, Hayley C., Heavey, Susan
Publicado 2020

Author Correction: Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer

por Luszczak, Sabina, Simpson, Benjamin S., Stopka-Farooqui, Urszula, Sathyadevan, Vignesh Krishna, Echeverria, Lina M. Carmona, Kumar, Christopher, Costa, Helena, Haider, Aiman, Freeman, Alex, Jameson, Charles, Ratynska, Marzena, Ben-Salha, Imen, Sridhar, Ashwin, Shaw, Greg, Kelly, John D., Pye, Hayley, Gately, Kathy A., Whitaker, Hayley C., Heavey, Susan
Publicado 2020

Identification and clinical impact of potentially actionable somatic oncogenic mutations in solid tumor samples

por Toomey, Sinead, Carr, Aoife, Mezynski, Mateusz Janusz, Elamin, Yasir, Rafee, Shereen, Cremona, Mattia, Morgan, Clare, Madden, Stephen, Abdul-Jalil, Khairun I., Gately, Kathy, Farrelly, Angela, Kay, Elaine W., Kennedy, Susan, O’Byrne, Kenneth, Grogan, Liam, Breathnach, Oscar, Morris, Patrick G., Eustace, Alexander J., Fay, Joanna, Cummins, Robert, O’Grady, Anthony, Kalachand, Roshni, O’Donovan, Norma, Kelleher, Fergal, O’Reilly, Aine, Doherty, Mark, Crown, John, Hennessy, Bryan T.
Publicado 2020