Investigation of CYP3A induction by PF‐05251749 in early clinical development: comparison of linear slope physiologically based pharmacokinetic prediction and biomarker response

por Lin, Jian, Gaudreault, Francois, Johnson, Nathaniel, Lin, Zhiwu, Nouri, Parya, Goosen, Theunis C., Sawant‐Basak, Aarti
Publicado 2022

Systems approach reveals photosensitivity and PER2 level as determinants of clock‐modulator efficacy

por Kim, Dae Wook, Chang, Cheng, Chen, Xian, Doran, Angela C, Gaudreault, Francois, Wager, Travis, DeMarco, George J, Kim, Jae Kyoung
Publicado 2019