Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation

por Gaughan, Luke, Logan, Ian R., Neal, David E., Robson, Craig N.
Publicado 2005

The Histone Demethylase Enzymes KDM3A and KDM4B Co-Operatively Regulate Chromatin Transactions of the Estrogen Receptor in Breast Cancer

por Jones, Dominic, Wilson, Laura, Thomas, Huw, Gaughan, Luke, Wade, Mark A.
Publicado 2019

Correction to ‘Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation’

por Gaughan, Luke, Logan, Ian R, Neal, David E, Robson, Craig N
Publicado 2021

Aurora A regulates expression of AR-V7 in models of castrate resistant prostate cancer

por Jones, Dominic, Noble, Martin, Wedge, Steve R., Robson, Craig N., Gaughan, Luke
Publicado 2017

Deubiquitinating enzyme Usp12 regulates the interaction between the androgen receptor and the Akt pathway

por McClurg, Urszula L., Summerscales, Emma E., Harle, Victoria J., Gaughan, Luke, Robson, Craig N.
Publicado 2014

FOXA1 regulates androgen receptor variant activity in models of castrate-resistant prostate cancer

por Jones, Dominic, Wade, Mark, Nakjang, Sirintra, Chaytor, Lewis, Grey, James, Robson, Craig N., Gaughan, Luke
Publicado 2015

Engineering prostate cancer in vitro: what does it take?

por Buskin, Adriana, Scott, Emma, Nelson, Ryan, Gaughan, Luke, Robson, Craig N., Heer, Rakesh, Hepburn, Anastasia C.
Publicado 2023

The histone demethylase enzyme KDM3A is a key estrogen receptor regulator in breast cancer

por Wade, Mark A., Jones, Dominic, Wilson, Laura, Stockley, Jacqueline, Coffey, Kelly, Robson, Craig N., Gaughan, Luke
Publicado 2015

Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors

por Mills, Ian G., Gaughan, Luke, Robson, Craig, Ross, Theodora, McCracken, Stuart, Kelly, John, Neal, David E.
Publicado 2005

Differential regulation of the androgen receptor by protein phosphatase regulatory subunits

por Grey, James, Jones, Dominic, Wilson, Laura, Nakjang, Sirintra, Clayton, Jake, Temperley, Richard, Clark, Emma, Gaughan, Luke, Robson, Craig
Publicado 2017

A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities

por Kounatidou, Evangelia, Nakjang, Sirintra, McCracken, Stuart R C, Dehm, Scott M, Robson, Craig N, Jones, Dominic, Gaughan, Luke
Publicado 2019

Nutlin-3 inhibits androgen receptor-driven c-FLIP expression, resulting in apoptosis of prostate cancer cells

por Logan, Ian R., McClurg, Urszula L., Jones, Dominic L., O'Neill, Daniel J., Shaheen, Fadhel S., Lunec, John, Gaughan, Luke, Robson, Craig N.
Publicado 2016

Targeting the DNA Double Strand Break Repair Machinery in Prostate Cancer

por Shaheen, Fadhel S., Znojek, Pawel, Fisher, Ann, Webster, Martin, Plummer, Ruth, Gaughan, Luke, Smith, Graeme C. M., Leung, Hing Y., Curtin, Nicola J., Robson, Craig N.
Publicado 2011

KDM4B is a Master Regulator of the Estrogen Receptor Signalling Cascade

por Gaughan, Luke, Stockley, Jacqueline, Coffey, Kelly, O’Neill, Daniel, Jones, Dominic L., Wade, Mark, Wright, Jamie, Moore, Madeleine, Tse, Sandy, Rogerson, Lynsey, Robson, Craig N.
Publicado 2013

SETD6 controls the expression of estrogen-responsive genes and proliferation of breast carcinoma cells

por O'Neill, Daniel J, Williamson, Stuart Charles, Alkharaif, Dhuha, Monteiro, Isabella Christina Mazzaro, Goudreault, Marilyn, Gaughan, Luke, Robson, Craig N, Gingras, Anne-Claude, Binda, Olivier
Publicado 2014

Ubiquitin-specific protease 12 interacting partners Uaf-1 and WDR20 are potential therapeutic targets in prostate cancer

por McClurg, Urszula L., Harle, Victoria J., Nabbi, Arash, Batalha-Pereira, Amanda, Walker, Scott, Coffey, Kelly, Gaughan, Luke, McCracken, Stuart RC, Robson, Craig N.
Publicado 2015

Development and exploitation of a novel mutant androgen receptor modelling strategy to identify new targets for advanced prostate cancer therapy

por O'Neill, Daniel, Jones, Dominic, Wade, Mark, Grey, James, Nakjang, Sirintra, Guo, Wenrui, Cork, David, Davies, Barry R., Wedge, Steve R., Robson, Craig N., Gaughan, Luke
Publicado 2015

Identification of a novel K311 ubiquitination site critical for androgen receptor transcriptional activity

por McClurg, Urszula L., Cork, David M.W., Darby, Steven, Ryan-Munden, Claudia A., Nakjang, Sirintra, Mendes Côrtes, Leticia, Treumann, Achim, Gaughan, Luke, Robson, Craig N.
Publicado 2017

Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation

por Harris, Rebecca J., Heer, Maninder, Levasseur, Mark D., Cartwright, Tyrell N., Weston, Bethany, Mitchell, Jennifer L., Coxhead, Jonathan M., Gaughan, Luke, Prendergast, Lisa, Rico, Daniel, Higgins, Jonathan M. G.
Publicado 2023

Regulation of the androgen receptor by SET9-mediated methylation

por Gaughan, Luke, Stockley, Jacqueline, Wang, Nan, McCracken, Stuart R.C., Treumann, Achim, Armstrong, Kelly, Shaheen, Fadhel, Watt, Kate, McEwan, Iain J., Wang, Chenguang, Pestell, Richard G., Robson, Craig N.
Publicado 2011