GTS-21, an α7nAChR agonist, increases pulmonary bacterial clearance in mice by restoring hyperoxia-compromised macrophage function

por Sitapara, Ravikumar A., Gauthier, Alex G., Patel, Vivek S., Lin, Mosi, Zur, Michelle, Ashby, Charles R., Mantell, Lin L.
Publicado 2020

Correction to: GTS-21, an α7nAChR agonist, increases pulmonary bacterial clearance in mice by restoring hyperoxia-compromised macrophage function

por Sitapara, Ravikumar A., Gauthier, Alex G., Patel, Vivek S., Lin, Mosi, Zur, Michelle, Ashby, Charles R., Mantell, Lin L.
Publicado 2021

GAT107-mediated α7 nicotinic acetylcholine receptor signaling attenuates inflammatory lung injury and mortality in a mouse model of ventilator-associated pneumonia by alleviating m...

por Gauthier, Alex G., Lin, Mosi, Zefi, Sidorela, Kulkarni, Abhijit, Thakur, Ganesh A., Ashby, Charles R., Mantell, Lin L.
Publicado 2023

Dietary Antioxidants Significantly Attenuate Hyperoxia-Induced Acute Inflammatory Lung Injury by Enhancing Macrophage Function via Reducing the Accumulation of Airway HMGB1

por Patel, Vivek, Dial, Katelyn, Wu, Jiaqi, Gauthier, Alex G., Wu, Wenjun, Lin, Mosi, Espey, Michael G., Thomas, Douglas D., Ashby, Charles R., Mantell, Lin L.
Publicado 2020

The Positive Allosteric Modulation of alpha7-Nicotinic Cholinergic Receptors by GAT107 Increases Bacterial Lung Clearance in Hyperoxic Mice by Decreasing Oxidative Stress in Macrop...

por Gauthier, Alex G., Wu, Jiaqi, Lin, Mosi, Sitapara, Ravikumar, Kulkarni, Abhijit, Thakur, Ganesh A., Schmidt, Edward E., Perron, Jeanette C., Ashby, Charles R., Mantell, Lin L.
Publicado 2021

The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the...

por Sitapara, Ravikumar A., Gauthier, Alex G., Valdés-Ferrer, Sergio I., Lin, Mosi, Patel, Vivek, Wang, Mao, Martino, Ashley T., Perron, Jeanette C., Ashby, Charles R., Tracey, Kevin J., Pavlov, Valentin A., Mantell, Lin L.
Publicado 2020

2-O, 3-O desulfated heparin (ODSH) increases bacterial clearance and attenuates lung injury in cystic fibrosis by restoring HMGB1-compromised macrophage function

por Wang, Mao, Gauthier, Alex G., Kennedy, Thomas P., Wang, Haichao, Velagapudi, Uday Kiran, Talele, Tanaji T., Lin, Mosi, Wu, Jiaqi, Daley, LeeAnne, Yang, Xiaojing, Patel, Vivek, Mun, Sung Soo, Ashby, Charles R., Mantell, Lin L.
Publicado 2021

Correction to: 2‑O, 3‑O desulfated heparin (ODSH) increases bacterial clearance and attenuates lung injury in cystic fibrosis by restoring HMGB1‑compromised macrophage function...

por Wang, Mao, Gauthier, Alex G., Kennedy, Thomas P., Wang, Haichao, Velagapudi, Uday Kiran, Talele, Tanaji T., Lin, Mosi, Wu, Jiaqi, Daley, LeeAnne, Yang, Xiaojing, Patel, Vivek, Mun, Sung Soo, Ashby, Charles R., Mantell, Lin L.
Publicado 2021