The crystal structure of human forkhead box N1 in complex with DNA reveals the structural basis for forkhead box family specificity

por Newman, Joseph A., Aitkenhead, Hazel, Gavard, Angeline E., Rota, Ioanna A., Handel, Adam E., Hollander, Georg A., Gileadi, Opher
Publicado 2020

Application of particle swarm optimization to understand the mechanism of action of allosteric inhibitors of the enzyme HSD17β13

por Ford, Amy, Breitgoff, Frauke, Pasquini, Miriam, MacKenzie, Amanda, McElroy, Stuart, Baker, Steve, Abrusci, Patrizia, Varzandeh, Simon, Bird, Louise, Gavard, Angeline, Damerell, David, Redhead, Martin
Publicado 2023

Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition

por Yosaatmadja, Yuliana, Baddock, Hannah T, Newman, Joseph A, Bielinski, Marcin, Gavard, Angeline E, Mukhopadhyay, Shubhashish M M, Dannerfjord, Adam A, Schofield, Christopher J, McHugh, Peter J, Gileadi, Opher
Publicado 2021

Structure of the helicase core of Werner helicase, a key target in microsatellite instability cancers

por Newman, Joseph A, Gavard, Angeline E, Lieb, Simone, Ravichandran, Madhwesh C, Hauer, Katja, Werni, Patrick, Geist, Leonhard, Böttcher, Jark, Engen, John R, Rumpel, Klaus, Samwer, Matthias, Petronczki, Mark, Gileadi, Opher
Publicado 2020