Antibodies to the Extracellular Pore Loop of TRPM8 Act as Antagonists of Channel Activation

por Miller, Silke, Rao, Sara, Wang, Weiya, Liu, Hantao, Wang, Judy, Gavva, Narender R.
Publicado 2014

Transient receptor potential melastatin 8 (TRPM8) channels are involved in body temperature regulation

por Gavva, Narender R, Davis, Carl, Lehto, Sonya G, Rao, Sara, Wang, Weiya, Zhu, Dawn XD
Publicado 2012

Species-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists

por Klionsky, Lana, Tamir, Rami, Gao, BaoXi, Wang, Weiya, Immke, David C, Nishimura, Nobuko, Gavva, Narender R
Publicado 2007

Reduced TRPM8 expression underpins reduced migraine risk and attenuated cold pain sensation in humans

por Gavva, Narender R., Sandrock, Robert, Arnold, Gregory E., Davis, Michael, Lamas, Edwin, Lindvay, Chris, Li, Chi-Ming, Smith, Brian, Backonja, Miroslav, Gabriel, Kristin, Vargas, Gabriel
Publicado 2019

Genome-wide CRISPR Screening to Identify Drivers of TGF-β-Induced Liver Fibrosis in Human Hepatic Stellate Cells

por Yu, Shan, Ericson, Matthew, Fanjul, Andrea, Erion, Derek M., Paraskevopoulou, Maria, Smith, Erin N., Cole, Banumathi, Feaver, Ryan, Holub, Corine, Gavva, Narender, Horman, Shane R., Huang, Jie
Publicado 2022

AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia

por Lehto, Sonya G., Weyer, Andy D., Zhang, Maosheng, Youngblood, Beth D., Wang, Judy, Wang, Weiya, Kerstein, Patrick C., Davis, Carl, Wild, Kenneth D., Stucky, Cheryl L., Gavva, Narender R.
Publicado 2015

Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats

por Lehto, Sonya G, Weyer, Andy D, Youngblood, Beth D, Zhang, Maosheng, Yin, Ruoyuan, Wang, Weiya, Teffera, Yohannes, Cooke, Melanie, Stucky, Cheryl L, Schenkel, Laurie, Geuns-Meyer, Stephanie, Moyer, Bryan D, Wild, Kenneth D, Gavva, Narender R
Publicado 2016