Role of self-organising myddosome oligomers in inflammatory signalling by Toll-like receptors

por Gay, Nicholas J.
Publicado 2019

Molecular and Cellular Regulation of Toll-Like Receptor-4 Activity Induced by Lipopolysaccharide Ligands

por Liaunardy-Jopeace, Ardiyanto, Gay, Nicholas J.
Publicado 2014

Liesegang-like patterns of Toll crystals grown in gel

por Gangloff, Monique, Moreno, Abel, Gay, Nicholas J.
Publicado 2013

Activation of Toll-like receptor 4 by Ebola virus-shed glycoprotein is direct and requires the internal fusion loop but not glycosylation

por Scherm, Michael J., Gangloff, Monique, Gay, Nicholas J.
Publicado 2022

Functional Insights from the Crystal Structure of the N-Terminal Domain of the Prototypical Toll Receptor

por Gangloff, Monique, Arnot, Christopher J., Lewis, Miranda, Gay, Nicholas J.
Publicado 2013

Targeting and Recognition of Toll-Like Receptors by Plant and Pathogen Lectins

por Ricci-Azevedo, Rafael, Roque-Barreira, Maria-Cristina, Gay, Nicholas J.
Publicado 2017

Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR)...

por Halabi, Samer, Sekine, Eiki, Verstak, Brett, Gay, Nicholas J., Moncrieffe, Martin C.
Publicado 2017

Toll-like receptor 2 promiscuity is responsible for the immunostimulatory activity of nucleic acid nanocarriers

por Pizzuto, Malvina, Gangloff, Monique, Scherman, Daniel, Gay, Nicholas J., Escriou, Virginie, Ruysschaert, Jean-Marie, Lonez, Caroline
Publicado 2017

Identification of Key Residues That Confer Rhodobacter sphaeroides LPS Activity at Horse TLR4/MD-2

por Irvine, Katherine L., Gangloff, Monique, Walsh, Catherine M., Spring, David R., Gay, Nicholas J., Bryant, Clare E.
Publicado 2014

Negative Regulation of TLR Signaling by BCAP Requires Dimerization of Its DBB Domain

por Lauenstein, Johannes U., Scherm, Michael J., Udgata, Atul, Moncrieffe, Martin C., Fisher, David I., Gay, Nicholas J.
Publicado 2020

Structure of the Glycosyltransferase EryCIII in Complex with its Activating P450 Homologue EryCII

por Moncrieffe, Martin C., Fernandez, Maria-Jose, Spiteller, Dieter, Matsumura, Hiroyoshi, Gay, Nicholas J., Luisi, Ben F., Leadlay, Peter F.
Publicado 2012

The Parkinson's disease–associated kinase LRRK2 regulates genes required for cell adhesion, polarization, and chemotaxis in activated murine macrophages

por Levy, Daniel R., Udgata, Atul, Tourlomousis, Panagiotis, Symmons, Martyn F., Hopkins, Lee J., Bryant, Clare E., Gay, Nicholas J.
Publicado 2020

Toll-6 and Toll-7 function as neurotrophin receptors in the Drosophila central nervous system

por McIlroy, Graham, Foldi, Istvan, Aurikko, Jukka, Wentzell, Jill S., Lim, Mei Ann, Fenton, Janine C., Gay, Nicholas J., Hidalgo, Alicia
Publicado 2013

Phosphorylation of the multifunctional signal transducer B-cell adaptor protein (BCAP) promotes recruitment of multiple SH2/SH3 proteins including GRB2

por Lauenstein, Johannes U., Udgata, Atul, Bartram, Alex, De Sutter, Delphine, Fisher, David I., Halabi, Samer, Eyckerman, Sven, Gay, Nicholas J.
Publicado 2019

MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling

por Moncrieffe, Martin C., Bollschweiler, Daniel, Li, Bing, Penczek, Pawel A., Hopkins, Lee, Bryant, Clare E., Klenerman, David, Gay, Nicholas J.
Publicado 2020

A Quantitative Comparison of Single-Dye Tracking Analysis Tools Using Monte Carlo Simulations

por Weimann, Laura, Ganzinger, Kristina A., McColl, James, Irvine, Kate L., Davis, Simon J., Gay, Nicholas J., Bryant, Clare E., Klenerman, David
Publicado 2013

A Dimer of the Toll-Like Receptor 4 Cytoplasmic Domain Provides a Specific Scaffold for the Recruitment of Signalling Adaptor Proteins

por Núñez Miguel, Ricardo, Wong, Joyce, Westoll, Julian F., Brooks, Heather J., O'Neill, Luke A.J., Gay, Nicholas J., Bryant, Clare E., Monie, Tom P.
Publicado 2007

Two Human MYD88 Variants, S34Y and R98C, Interfere with MyD88-IRAK4-Myddosome Assembly

por George, Julie, Motshwene, Precious G., Wang, Hui, Kubarenko, Andriy V., Rautanen, Anna, Mills, Tara C., Hill, Adrian V. S., Gay, Nicholas J., Weber, Alexander N. R.
Publicado 2011

Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4

por Pizzuto, Malvina, Lonez, Caroline, Baroja-Mazo, Alberto, Martínez-Banaclocha, Helios, Tourlomousis, Panagiotis, Gangloff, Monique, Pelegrin, Pablo, Ruysschaert, Jean-Marie, Gay, Nicholas J., Bryant, Clare E.
Publicado 2019

The N-terminal loop of IRAK-4 death domain regulates ordered assembly of the Myddosome signalling scaffold

por Dossang, Anthony C. G., Motshwene, Precious G., Yang, Yang, Symmons, Martyn F., Bryant, Clare E., Borman, Satty, George, Julie, Weber, Alexander N. R., Gay, Nicholas J.
Publicado 2016