Discovery of Emphysema Relevant Molecular Networks from an A/J Mouse Inhalation Study Using Reverse Engineering and Forward Simulation (REFS™)

por Xiang, Yang, Kogel, Ulrike, Gebel, Stephan, Peck, Michael J., Peitsch, Manuel C., Akmaev, Viatcheslav R., Hoeng, Julia
Publicado 2014

Integration and Visualization of Translational Medicine Data for Better Understanding of Human Diseases

por Satagopam, Venkata, Gu, Wei, Eifes, Serge, Gawron, Piotr, Ostaszewski, Marek, Gebel, Stephan, Barbosa-Silva, Adriano, Balling, Rudi, Schneider, Reinhard
Publicado 2016

Design of the formalized and integrated Alzheimer’s Disease Ontology and its application in retrieving textual data via text mining

por Zhang, Bide, Lage-Rupprecht, Vanessa, Wegner, Philipp, Sargsyan, Astghik, Gebel, Stephan, Jacobs, Marc, Klein, Jürgen, Hofmann-Apitius, Martin, Tom Kodamullil, Alpha
Publicado 2023

A Systems Biology Approach Reveals the Dose- and Time-Dependent Effect of Primary Human Airway Epithelium Tissue Culture After Exposure to Cigarette Smoke In Vitro

por Mathis, Carole, Gebel, Stephan, Poussin, Carine, Belcastro, Vincenzo, Sewer, Alain, Weisensee, Dirk, Hengstermann, Arnd, Ansari, Sam, Wagner, Sandra, Peitsch, Manuel C, Hoeng, Julia
Publicado 2015

MINERVA—a platform for visualization and curation of molecular interaction networks

por Gawron, Piotr, Ostaszewski, Marek, Satagopam, Venkata, Gebel, Stephan, Mazein, Alexander, Kuzma, Michal, Zorzan, Simone, McGee, Fintan, Otjacques, Benoît, Balling, Rudi, Schneider, Reinhard
Publicado 2016

Lung Inflammatory Effects, Tumorigenesis, and Emphysema Development in a Long-Term Inhalation Study with Cigarette Mainstream Smoke in Mice

por Stinn, Walter, Buettner, Ansgar, Weiler, Horst, Friedrichs, Baerbel, Luetjen, Sonja, van Overveld, Frans, Meurrens, Kris, Janssens, Kris, Gebel, Stephan, Stabbert, Regina, Haussmann, Hans-Juergen
Publicado 2013

Systematic Verification of Upstream Regulators of a Computable Cellular Proliferation Network Model on Non-Diseased Lung Cells Using a Dedicated Dataset

por Belcastro, Vincenzo, Poussin, Carine, Gebel, Stephan, Mathis, Carole, Schlage, Walter K., Lichtner, Rosemarie B., Quadt-Humme, Sibille, Wagner, Sandra, Hoeng, Julia, Peitsch, Manuel C.
Publicado 2013

CTO: a Community-Based Clinical Trial Ontology and its Applications in PubChemRDF and SCAIView

por LIN, Asiyah Yu, GEBEL, Stephan, LI, Qingliang Leon, MADAN, Sumit, DARMS, Johannes, BOLTON, Evan, SMITH, Barry, HOFMANN-APITIUS, Martin, HE, Yongqun Oliver, KODAMULLIL, Alpha Tom
Publicado 2020

Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative Disorders

por Hofmann-Apitius, Martin, Ball, Gordon, Gebel, Stephan, Bagewadi, Shweta, de Bono, Bernard, Schneider, Reinhard, Page, Matt, Kodamullil, Alpha Tom, Younesi, Erfan, Ebeling, Christian, Tegnér, Jesper, Canard, Luc
Publicado 2015

The Epilepsy Ontology: a community-based ontology tailored for semantic interoperability and text mining

por Sargsyan, Astghik, Wegner, Philipp, Gebel, Stephan, Kaladharan, Abish, Sethumadhavan, Priya, Lage-Rupprecht, Vanessa, Darms, Johannes, Schultz, Bruce, Klein, Jürgen, Jacobs, Marc, Madan, Sumit, Hofmann-Apitius, Martin, Kodamullil, Alpha Tom
Publicado 2023

Integrative data semantics through a model-enabled data stewardship

por Wegner, Philipp, Schaaf, Sebastian, Uebachs, Mischa, Domingo-Fernández, Daniel, Salimi, Yasamin, Gebel, Stephan, Sargsyan, Astghik, Birkenbihl, Colin, Springstubbe, Stephan, Klockgether, Thomas, Fluck, Juliane, Hofmann-Apitius, Martin, Kodamullil, Alpha Tom
Publicado 2022

A hybrid approach unveils drug repurposing candidates targeting an Alzheimer pathophysiology mechanism

por Lage-Rupprecht, Vanessa, Schultz, Bruce, Dick, Justus, Namysl, Marcin, Zaliani, Andrea, Gebel, Stephan, Pless, Ole, Reinshagen, Jeanette, Ellinger, Bernhard, Ebeling, Christian, Esser, Alexander, Jacobs, Marc, Claussen, Carsten, Hofmann-Apitius, Martin
Publicado 2022

The COVID-19 Ontology

por Sargsyan, Astghik, Kodamullil, Alpha Tom, Baksi, Shounak, Darms, Johannes, Madan, Sumit, Gebel, Stephan, Keminer, Oliver, Jose, Geena Mariya, Balabin, Helena, DeLong, Lauren Nicole, Kohler, Manfred, Jacobs, Marc, Hofmann-Apitius, Martin
Publicado 2020

Construction of a Computable Network Model for DNA Damage, Autophagy, Cell Death, and Senescence

por Gebel, Stephan, Lichtner, Rosemarie B., Frushour, Brian, Schlage, Walter K., Hoang, Vy, Talikka, Marja, Hengstermann, Arnd, Mathis, Carole, Veljkovic, Emilija, Peck, Michael, Peitsch, Manuel C., Deehan, Renee, Hoeng, Julia, Westra, Jurjen W.
Publicado 2013

A Modular Cell-Type Focused Inflammatory Process Network Model for Non-Diseased Pulmonary Tissue

por Westra, Jurjen W., Schlage, Walter K., Hengstermann, Arnd, Gebel, Stephan, Mathis, Carole, Thomson, Ty, Wong, Ben, Hoang, Vy, Veljkovic, Emilija, Peck, Michael, Lichtner, Rosemarie B., Weisensee, Dirk, Talikka, Marja, Deehan, Renee, Hoeng, Julia, Peitsch, Manuel C.
Publicado 2013

Community-driven roadmap for integrated disease maps

por Ostaszewski, Marek, Gebel, Stephan, Kuperstein, Inna, Mazein, Alexander, Zinovyev, Andrei, Dogrusoz, Ugur, Hasenauer, Jan, Fleming, Ronan M T, Le Novère, Nicolas, Gawron, Piotr, Ligon, Thomas, Niarakis, Anna, Nickerson, David, Weindl, Daniel, Balling, Rudi, Barillot, Emmanuel, Auffray, Charles, Schneider, Reinhard
Publicado 2018

A computable cellular stress network model for non-diseased pulmonary and cardiovascular tissue

por Schlage, Walter K, Westra, Jurjen W, Gebel, Stephan, Catlett, Natalie L, Mathis, Carole, Frushour, Brian P, Hengstermann, Arnd, Van Hooser, Aaron, Poussin, Carine, Wong, Ben, Lietz, Michael, Park, Jennifer, Drubin, David, Veljkovic, Emilija, Peitsch, Manuel C, Hoeng, Julia, Deehan, Renee
Publicado 2011

A vascular biology network model focused on inflammatory processes to investigate atherogenesis and plaque instability

por De León, Héctor, Boué, Stéphanie, Schlage, Walter K, Boukharov, Natalia, Westra, Jurjen W, Gebel, Stephan, VanHooser, Aaron, Talikka, Marja, Fields, R Brett, Veljkovic, Emilija, Peck, Michael J, Mathis, Carole, Hoang, Vy, Poussin, Carine, Deehan, Renee, Stolle, Katrin, Hoeng, Julia, Peitsch, Manuel C
Publicado 2014

Construction of a computable cell proliferation network focused on non-diseased lung cells

por Westra, Jurjen W, Schlage, Walter K, Frushour, Brian P, Gebel, Stephan, Catlett, Natalie L, Han, Wanjiang, Eddy, Sean F, Hengstermann, Arnd, Matthews, Andrea L, Mathis, Carole, Lichtner, Rosemarie B, Poussin, Carine, Talikka, Marja, Veljkovic, Emilija, Van Hooser, Aaron A, Wong, Benjamin, Maria, Michael J, Peitsch, Manuel C, Deehan, Renee, Hoeng, Julia
Publicado 2011

Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms

por Mazein, Alexander, Ostaszewski, Marek, Kuperstein, Inna, Watterson, Steven, Le Novère, Nicolas, Lefaudeux, Diane, De Meulder, Bertrand, Pellet, Johann, Balaur, Irina, Saqi, Mansoor, Nogueira, Maria Manuela, He, Feng, Parton, Andrew, Lemonnier, Nathanaël, Gawron, Piotr, Gebel, Stephan, Hainaut, Pierre, Ollert, Markus, Dogrusoz, Ugur, Barillot, Emmanuel, Zinovyev, Andrei, Schneider, Reinhard, Balling, Rudi, Auffray, Charles
Publicado 2018