Simultaneous targeting of androgen receptor (AR) and MAPK-interacting kinases (MNKs) by novel retinamides inhibits growth of human prostate cancer cell lines

por Ramamurthy, Vidya P., Ramalingam, Senthilmurugan, Gediya, Lalji, Kwegyir-Afful, Andrew K., Njar, Vincent C.O.
Publicado 2014

Novel galeterone analogs act independently of AR and AR-V7 for the activation of the unfolded protein response and induction of apoptosis in the CWR22Rv1 prostate cancer cell model

por McCarty, David J., Huang, Weiliang, Kane, Maureen A., Purushottamachar, Puranik, Gediya, Lalji K., Njar, Vincent C.O.
Publicado 2017

First Mnks degrading agents block phosphorylation of eIF4E, induce apoptosis, inhibit cell growth, migration and invasion in triple negative and Her2-overexpressing breast cancer c...

por Ramalingam, Senthilmurugan, Gediya, Lalji, Kwegyir-Afful, Andrew K., Ramamurthy, Vidya P., Purushottamachar, Puranik, Mbatia, Hannah, Njar, Vincent C. O.
Publicado 2014

The Novel Mnk1/2 Degrader and Apoptosis Inducer VNLG-152 Potently Inhibits TNBC Tumor Growth and Metastasis

por Ramalingam, Senthilmurugan, Ramamurthy, Vidya P., Gediya, Lalji K., Murigi, Francis N., Purushottamachar, Puranik, Huang, Weiliang, Choi, Eun Yong, Zhang, Yuji, Vasaitis, Tadas S, Kane, Maureen A., Lapidus, Rena G., Njar, Vincent C. O.
Publicado 2019