The importance of being connected: membrane contact sites and Parkinson’s disease

por Gegg, Matthew E.
Publicado 2023

The role of DJ-1 complexes and catecholamine metabolism: relevance for familial and idiopathic Parkinson’s disease

por Piston, Dominik, Gegg, Matthew E.
Publicado 2018

Mitochondrial dysfunction associated with glucocerebrosidase deficiency

por Gegg, Matthew E., Schapira, Anthony H.V.
Publicado 2016

Glucocerebrosidase deficiency promotes release of α-synuclein fibrils from cultured neurons

por Gegg, Matthew E, Verona, Guglielmo, Schapira, Anthony H V
Publicado 2020

Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin‐mediated mitophagy

por Ivankovic, Davor, Chau, Kai‐Yin, Schapira, Anthony H. V., Gegg, Matthew E.
Publicado 2015

Silencing of PINK1 Expression Affects Mitochondrial DNA and Oxidative Phosphorylation in DOPAMINERGIC Cells

por Gegg, Matthew E., Cooper, J. Mark, Schapira, Anthony H. V., Taanman, Jan-Willem
Publicado 2009

The GBA variant E326K is associated with alpha-synuclein aggregation and lipid droplet accumulation in human cell lines

por Smith, Laura J, Bolsinger, Magdalena M, Chau, Kai-Yin, Gegg, Matthew E, Schapira, Anthony H V
Publicado 2022

No evidence for substrate accumulation in Parkinson brains with GBA mutations

por Gegg, Matthew E., Sweet, Lindsay, Wang, Bing H., Shihabuddin, Lamya S., Sardi, Sergio Pablo, Schapira, Anthony H.V.
Publicado 2015

Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models

por Sanchez-Martinez, Alvaro, Beavan, Michelle, Gegg, Matthew E., Chau, Kai-Yin, Whitworth, Alexander J., Schapira, Anthony H. V.
Publicado 2016

Mitochondria: Key Organelle in Parkinson's Disease

por Gómez-Sánchez, Rubén, Bravo-San Pedro, José M., Gegg, Matthew E., González-Polo, Rosa A., Fuentes, José M.
Publicado 2016

Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease

por Magalhaes, Joana, Gegg, Matthew E., Migdalska-Richards, Anna, Doherty, Mary K., Whitfield, Phillip D., Schapira, Anthony H.V.
Publicado 2016

Glucocerebrosidase Deficiency in Substantia Nigra of Parkinson Disease Brains

por Gegg, Matthew E, Burke, Derek, Heales, Simon J R, Cooper, J Mark, Hardy, John, Wood, Nicholas W, Schapira, Anthony H V
Publicado 2012

α-Synuclein expression in response to bacterial ligands and metabolites in gut enteroendocrine cells: an in vitro proof of concept study

por Hurley, Michael J, Menozzi, Elisa, Koletsi, Sofia, Bates, Rachel, Gegg, Matthew E, Chau, Kai-Yin, Blottière, Hervé M, Macnaughtan, Jane, Schapira, Anthony H V
Publicado 2023

Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease—Links to Parkinson’s Disease

por Osellame, Laura D., Rahim, Ahad A., Hargreaves, Iain P., Gegg, Matthew E., Richard-Londt, Angela, Brandner, Sebastian, Waddington, Simon N., Schapira, Anthony H.V., Duchen, Michael R.
Publicado 2013

Endoplasmic reticulum and lysosomal Ca(2+) stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts

por Kilpatrick, Bethan S., Magalhaes, Joana, Beavan, Michelle S., McNeill, Alisdair, Gegg, Matthew E., Cleeter, Michael W.J., Bloor-Young, Duncan, Churchill, Grant C., Duchen, Michael R., Schapira, Anthony H., Patel, Sandip
Publicado 2016

Unexpected phenotypic and molecular changes of combined glucocerebrosidase and acid sphingomyelinase deficiency

por Keatinge, Marcus, Gegg, Matthew E., Watson, Lisa, Mortiboys, Heather, Li, Nan, Dunning, Mark, Ailani, Deepak, Bui, Hai, van Rens, Astrid, Lefeber, Dirk J., Schapira, Anthony H. V., MacDonald, Ryan B., Bandmann, Oliver
Publicado 2023

Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression()

por Gómez-Sánchez, Rubén, Gegg, Matthew E., Bravo-San Pedro, José M., Niso-Santano, Mireia, Alvarez-Erviti, Lydia, Pizarro-Estrella, Elisa, Gutiérrez-Martín, Yolanda, Alvarez-Barrientos, Alberto, Fuentes, José M., González-Polo, Rosa Ana, Schapira, Anthony H.V.
Publicado 2014

DJ-1 is a redox sensitive adapter protein for high molecular weight complexes involved in regulation of catecholamine homeostasis

por Piston, Dominik, Alvarez-Erviti, Lydia, Bansal, Vikas, Gargano, Daniela, Yao, Zhi, Szabadkai, Gyorgy, Odell, Mark, Puno, M Rhyan, Björkblom, Benny, Maple-Grødem, Jodi, Breuer, Peter, Kaut, Oliver, Larsen, Jan Petter, Bonn, Stefan, Møller, Simon Geir, Wüllner, Ullrich, Schapira, Anthony H V, Gegg, Matthew E
Publicado 2017

DJ-1 is a redox sensitive adapter protein for high molecular weight complexes involved in regulation of catecholamine homeostasis

por Piston, Dominik, Alvarez-Erviti, Lydia, Bansal, Vikas, Gargano, Daniela, Yao, Zhi, Szabadkai, Gyorgy, Odell, Mark, Puno, M Rhyan, Björkblom, Benny, Maple-Grødem, Jodi, Breuer, Peter, Kaut, Oliver, Larsen, Jan Petter, Bonn, Stefan, Møller, Simon Geir, Wüllner, Ullrich, Schapira, Anthony H V, Gegg, Matthew E
Publicado 2018