Efficient Targeted Degradation via Reversible and Irreversible Covalent PROTACs

por Gabizon, Ronen, Shraga, Amit, Gehrtz, Paul, Livnah, Ella, Shorer, Yamit, Gurwicz, Neta, Avram, Liat, Unger, Tamar, Aharoni, Hila, Albeck, Shira, Brandis, Alexander, Shulman, Ziv, Katz, Ben-Zion, Herishanu, Yair, London, Nir
Publicado 2020

Correction to Efficient Targeted Degradation via Reversible and Irreversible Covalent PROTACs

por Gabizon, Ronen, Shraga, Amit, Gehrtz, Paul, Livnah, Ella, Shorer, Yamit, Gurwicz, Neta, Avram, Liat, Unger, Tamar, Aharoni, Hila, Albeck, Shira, Brandis, Alexander, Shulman, Ziv, Katz, Ben-Zion, Herishanu, Yair, London, Nir
Publicado 2020

An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 M(pro) inhibitor

por Zaidman, Daniel, Gehrtz, Paul, Filep, Mihajlo, Fearon, Daren, Gabizon, Ronen, Douangamath, Alice, Prilusky, Jaime, Duberstein, Shirly, Cohen, Galit, Owen, C. David, Resnick, Efrat, Strain-Damerell, Claire, Lukacik, Petra, Barr, Haim, Walsh, Martin A., von Delft, Frank, London, Nir
Publicado 2021

Optimization of Covalent MKK7 Inhibitors via Crude Nanomole-Scale Libraries

por Gehrtz, Paul, Marom, Shir, Bührmann, Mike, Hardick, Julia, Kleinbölting, Silke, Shraga, Amit, Dubiella, Christian, Gabizon, Ronen, Wiese, Jan N., Müller, Matthias P., Cohen, Galit, Babaev, Ilana, Shurrush, Khriesto, Avram, Liat, Resnick, Efrat, Barr, Haim, Rauh, Daniel, London, Nir
Publicado 2022

Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease

por Douangamath, Alice, Fearon, Daren, Gehrtz, Paul, Krojer, Tobias, Lukacik, Petra, Owen, C. David, Resnick, Efrat, Strain-Damerell, Claire, Aimon, Anthony, Ábrányi-Balogh, Péter, Brandão-Neto, José, Carbery, Anna, Davison, Gemma, Dias, Alexandre, Downes, Thomas D., Dunnett, Louise, Fairhead, Michael, Firth, James D., Jones, S. Paul, Keeley, Aaron, Keserü, György M., Klein, Hanna F., Martin, Mathew P., Noble, Martin E. M., O’Brien, Peter, Powell, Ailsa, Reddi, Rambabu N., Skyner, Rachael, Snee, Matthew, Waring, Michael J., Wild, Conor, London, Nir, von Delft, Frank, Walsh, Martin A.
Publicado 2020