Genetic Variation in the Androgen Receptor and Measures of Plasma Testosterone Levels Suggest Androgen Dysfunction in Alzheimer’s Disease

por Carr, Jessie S., Bonham, Luke W., Morgans, Alicia K., Ryan, Charles J., Yokoyama, Jennifer S., Geier, Ethan G.
Publicado 2018

Profiling Solute Carrier Transporters in the Human Blood-Brain Barrier

por Geier, Ethan G., Chen, Eugene C., Webb, Amy, Papp, Audrey C., Yee, Sook Wah, Sadee, Wolfgang, Giacomini, Kathleen M.
Publicado 2013

Insulin-Like Growth Factor Binding Protein 2 Is Associated With Biomarkers of Alzheimer’s Disease Pathology and Shows Differential Expression in Transgenic Mice

por Bonham, Luke W., Geier, Ethan G., Steele, Natasha Z. R., Holland, Dominic, Miller, Bruce L., Dale, Anders M., Desikan, Rahul S., Yokoyama, Jennifer S.
Publicado 2018

SVIP is a molecular determinant of lysosomal dynamic stability, neurodegeneration and lifespan

por Johnson, Alyssa E., Orr, Brian O., Fetter, Richard D., Moughamian, Armen J., Primeaux, Logan A., Geier, Ethan G., Yokoyama, Jennifer S., Miller, Bruce L., Davis, Graeme W.
Publicado 2021

Rare TREM2 variants associated with Alzheimer’s disease display reduced cell surface expression

por Sirkis, Daniel W., Bonham, Luke W., Aparicio, Renan E., Geier, Ethan G., Ramos, Eliana Marisa, Wang, Qing, Karydas, Anna, Miller, Zachary A., Miller, Bruce L., Coppola, Giovanni, Yokoyama, Jennifer S.
Publicado 2016

Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy

por Sirkis, Daniel W., Warly Solsberg, Caroline, Johnson, Taylor P., Bonham, Luke W., Sturm, Virginia E., Lee, Suzee E., Rankin, Katherine P., Rosen, Howard J., Boxer, Adam L., Seeley, William W., Miller, Bruce L., Geier, Ethan G., Yokoyama, Jennifer S.
Publicado 2023

Evaluation of Norepinephrine Transporter Expression and Metaiodobenzylguanidine Avidity in Neuroblastoma: A Report from the Children's Oncology Group

por DuBois, Steven G., Geier, Ethan, Batra, Vandana, Yee, Sook Wah, Neuhaus, John, Segal, Mark, Martinez, Daniel, Pawel, Bruce, Yanik, Greg, Naranjo, Arlene, London, Wendy B., Kreissman, Susan, Baker, David, Attiyeh, Edward, Hogarty, Michael D., Maris, John M., Giacomini, Kathleen, Matthay, Katherine K.
Publicado 2012

Age‐dependent effects of APOE ε4 in preclinical Alzheimer's disease

por Bonham, Luke W., Geier, Ethan G., Fan, Chun C., Leong, Josiah K., Besser, Lilah, Kukull, Walter A., Kornak, John, Andreassen, Ole A., Schellenberg, Gerard D., Rosen, Howard J., Dillon, William P., Hess, Christopher P., Miller, Bruce L., Dale, Anders M., Desikan, Rahul S., Yokoyama, Jennifer S.
Publicado 2016

Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case–control study

por Steele, Natasha Z. R., Carr, Jessie S., Bonham, Luke W., Geier, Ethan G., Damotte, Vincent, Miller, Zachary A., Desikan, Rahul S., Boehme, Kevin L., Mukherjee, Shubhabrata, Crane, Paul K., Kauwe, John S. K., Kramer, Joel H., Miller, Bruce L., Coppola, Giovanni, Hollenbach, Jill A., Huang, Yadong, Yokoyama, Jennifer S.
Publicado 2017

Protein network analysis reveals selectively vulnerable regions and biological processes in FTD

por Bonham, Luke W., Steele, Natasha Z.R., Karch, Celeste M., Manzoni, Claudia, Geier, Ethan G., Wen, Natalie, Ofori-Kuragu, Aaron, Momeni, Parastoo, Hardy, John, Miller, Zachary A., Hess, Christopher P., Lewis, Patrick, Miller, Bruce L., Seeley, William W., Baranzini, Sergio E., Desikan, Rahul S., Ferrari, Raffaele, Yokoyama, Jennifer S.
Publicado 2018

Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia

por Bonham, Luke W., Steele, Natasha Z. R., Karch, Celeste M., Broce, Iris, Geier, Ethan G., Wen, Natalie L., Momeni, Parastoo, Hardy, John, Miller, Zachary A., Gorno-Tempini, Maria Luisa, Hess, Christopher P., Lewis, Patrick, Miller, Bruce L., Seeley, William W., Manzoni, Claudia, Desikan, Rahul S., Baranzini, Sergio E., Ferrari, Raffaele, Yokoyama, Jennifer S.
Publicado 2019

TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy

por Alquezar, Carolina, Schoch, Kathleen M., Geier, Ethan G., Ramos, Eliana Marisa, Scrivo, Aurora, Li, Kathy H., Argouarch, Andrea R., Mlynarski, Elisabeth E., Dombroski, Beth, DeTure, Michael, Dickson, Dennis W., Yokoyama, Jennifer S., Cuervo, Ana M., Burlingame, Alma L., Schellenberg, Gerard D., Miller, Timothy M., Miller, Bruce L., Kao, Aimee W.
Publicado 2021

Genome sequencing for early-onset or atypical dementia: high diagnostic yield and frequent observation of multiple contributory alleles

por Cochran, J. Nicholas, McKinley, Emily C., Cochran, Meagan, Amaral, Michelle D., Moyers, Bryan A., Lasseigne, Brittany N., Gray, David E., Lawlor, James M.J., Prokop, Jeremy W., Geier, Ethan G., Holt, James M., Thompson, Michelle L., Newberry, J. Scott, Yokoyama, Jennifer S., Worthey, Elizabeth A., Geldmacher, David S., Love, Marissa Natelson, Cooper, Gregory M., Myers, Richard M., Roberson, Erik D.
Publicado 2019

Early‐onset Alzheimer's disease explained by polygenic risk of late‐onset disease?

por Mantyh, William G., Cochran, J. Nicholas, Taylor, Jared W., Broce, Iris J., Geier, Ethan G., Bonham, Luke W., Anderson, Ashlyn G., Sirkis, Daniel W., Joie, Renaud La, Iaccarino, Leonardo, Chaudhary, Kiran, Edwards, Lauren, Strom, Amelia, Grant, Harli, Allen, Isabel E., Miller, Zachary A., Gorno‐Tempini, Marilu L., Kramer, Joel H., Miller, Bruce L., Desikan, Rahul S., Rabinovici, Gil D., Yokoyama, Jennifer S.
Publicado 2023

CXCR4 involvement in neurodegenerative diseases

por Bonham, Luke W., Karch, Celeste M., Fan, Chun C., Tan, Chin, Geier, Ethan G., Wang, Yunpeng, Wen, Natalie, Broce, Iris J., Li, Yi, Barkovich, Matthew J., Ferrari, Raffaele, Hardy, John, Momeni, Parastoo, Höglinger, Günter, Müller, Ulrich, Hess, Christopher P., Sugrue, Leo P., Dillon, William P., Schellenberg, Gerard D., Miller, Bruce L., Andreassen, Ole A., Dale, Anders M., Barkovich, A. James, Yokoyama, Jennifer S., Desikan, Rahul S.
Publicado 2018

Radiogenomics of C9orf72 Expansion Carriers Reveals Global Transposable Element Derepression and Enables Prediction of Thalamic Atrophy and Clinical Impairment

por Bonham, Luke W., Geier, Ethan G., Sirkis, Daniel W., Leong, Josiah K., Ramos, Eliana Marisa, Wang, Qing, Karydas, Anna, Lee, Suzee E., Sturm, Virginia E., Sawyer, Russell P., Friedberg, Adit, Ichida, Justin K., Gitler, Aaron D., Sugrue, Leo, Cordingley, Michael, Bee, Walter, Weber, Eckard, Kramer, Joel H., Rankin, Katherine P., Rosen, Howard J., Boxer, Adam L., Seeley, William W., Ravits, John, Miller, Bruce L., Yokoyama, Jennifer S.
Publicado 2023