ATRX is a regulator of therapy induced senescence in human cells

por Kovatcheva, Marta, Liao, Will, Klein, Mary E., Robine, Nicolas, Geiger, Heather, Crago, Aimee M., Dickson, Mark A., Tap, William D., Singer, Samuel, Koff, Andrew
Publicado 2017

Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma

por Rebbeck, Clare A., Xian, Jian, Bornelöv, Susanne, Geradts, Joseph, Hobeika, Amy, Geiger, Heather, Alvarez, Jose Franco, Rozhkova, Elena, Nicholls, Ashley, Robine, Nicolas, Lyerly, Herbert K., Hannon, Gregory J.
Publicado 2022

Identification of targetable BRAF ΔN486_P490 variant by whole-genome sequencing leading to dabrafenib-induced remission of a BRAF-mutant pancreatic adenocarcinoma

por Wrzeszczynski, Kazimierz O., Rahman, Sadia, Frank, Mayu O., Arora, Kanika, Shah, Minita, Geiger, Heather, Felice, Vanessa, Manaa, Dina, Dikoglu, Esra, Khaira, Depinder, Chimpiri, A. Rao, Michelini, Vanessa V., Jobanputra, Vaidehi, Darnell, Robert B., Powers, Scott, Choi, Minsig
Publicado 2019

Occult polyclonality of preclinical pancreatic cancer models drives in vitro evolution

por Monberg, Maria E., Geiger, Heather, Lee, Jaewon J., Sharma, Roshan, Semaan, Alexander, Bernard, Vincent, Wong, Justin, Wang, Fang, Liang, Shaoheng, Swartzlander, Daniel B., Stephens, Bret M., Katz, Matthew H. G., Chen, Ken, Robine, Nicolas, Guerrero, Paola A., Maitra, Anirban
Publicado 2022

Human papillomavirus and the landscape of secondary genetic alterations in oral cancers

por Gillison, Maura L., Akagi, Keiko, Xiao, Weihong, Jiang, Bo, Pickard, Robert K.L., Li, Jingfeng, Swanson, Benjamin J., Agrawal, Amit D., Zucker, Mark, Stache-Crain, Birgit, Emde, Anne-Katrin, Geiger, Heather M., Robine, Nicolas, Coombes, Kevin R., Symer, David E.
Publicado 2019

Metastatic pediatric sclerosing epithelioid fibrosarcoma

por Woods, Andrew D., Purohit, Reshma, Mitchell, Laura Crocker, Collier, John R., Collier, Katherine A., Lathara, Melvin, Learned, Katrina, Vaske, Olena, Geiger, Heather, Wrzeszczynski, Kazimierz O., Jobanputra, Vaidehi, Srinivasa, Ganapati, Rudzinski, Erin R., Whelan, Kimberly, Beierle, Elizabeth, Spunt, Sheri L., Keller, Charles, Wadhwa, Aman
Publicado 2021

Retromer dysfunction in amyotrophic lateral sclerosis

por Pérez-Torres, Eduardo J., Utkina-Sosunova, Irina, Mishra, Vartika, Barbuti, Peter, De Planell-Saguer, Mariangels, Dermentzaki, Georgia, Geiger, Heather, Basile, Anna O., Robine, Nicolas, Fagegaltier, Delphine, Politi, Kristin A., Rinchetti, Paola, Jackson-Lewis, Vernice, Harms, Matthew, Phatnani, Hemali, Lotti, Francesco, Przedborski, Serge
Publicado 2022

Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia

por McNeer, Nicole A., Philip, John, Geiger, Heather, Ries, Rhonda E., Lavallée, Vincent-Philippe, Walsh, Michael, Shah, Minita, Arora, Kanika, Emde, Anne-Katrin, Robine, Nicolas, Alonzo, Todd A, Kolb, E. Anders, Gamis, Alan S, Smith, Malcolm, Gerhard, Daniela Se, Guidry-Auvil, Jaime, Meshinchi, Soheil, Kentsis, Alex
Publicado 2019

A recurrent novel MGA–NUTM1 fusion identifies a new subtype of high-grade spindle cell sarcoma

por Diolaiti, Daniel, Dela Cruz, Filemon S., Gundem, Gunes, Bouvier, Nancy, Boulad, Mathieu, Zhang, Yanming, Chou, Alexander J., Dunkel, Ira J., Sanghvi, Rashesh, Shah, Minita, Geiger, Heather, Rahman, Sadia, Felice, Vanessa, Wrzeszczynski, Kazimierz O., Darnell, Robert B., Antonescu, Cristina R., French, Christopher A., Papaemmanuil, Elli, Kung, Andrew L., Shukla, Neerav
Publicado 2018

Analytical Validation of Clinical Whole-Genome and Transcriptome Sequencing of Patient-Derived Tumors for Reporting Targetable Variants in Cancer

por Wrzeszczynski, Kazimierz O., Felice, Vanessa, Abhyankar, Avinash, Kozon, Lukasz, Geiger, Heather, Manaa, Dina, London, Ferrah, Robinson, Dino, Fang, Xiaolan, Lin, David, Lamendola-Essel, Michelle F., Khaira, Depinder, Dikoglu, Esra, Emde, Anne-Katrin, Robine, Nicolas, Shah, Minita, Arora, Kanika, Basturk, Olca, Bhanot, Umesh, Kentsis, Alex, Mansukhani, Mahesh M., Bhagat, Govind, Jobanputra, Vaidehi
Publicado 2018

Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers

por Symer, David E., Akagi, Keiko, Geiger, Heather M., Song, Yang, Li, Gaiyun, Emde, Anne-Katrin, Xiao, Weihong, Jiang, Bo, Corvelo, André, Toussaint, Nora C., Li, Jingfeng, Agrawal, Amit, Ozer, Enver, El-Naggar, Adel K., Du, Zoe, Shewale, Jitesh B., Stache-Crain, Birgit, Zucker, Mark, Robine, Nicolas, Coombes, Kevin R., Gillison, Maura L.
Publicado 2022

Immunogenic neoantigens derived from gene fusions stimulate T cell responses

por Yang, Wei, Lee, Ken-Wing, Srivastava, Raghvendra M., Kuo, Fengshen, Krishna, Chirag, Chowell, Diego, Makarov, Vladimir, Hoen, Douglas, Dalin, Martin G., Wexler, Leonard, Ghossein, Ronald, Katabi, Nora, Nadeem, Zaineb, Cohen, Marc A., Tian, S. Ken, Robine, Nicolas, Arora, Kanika, Geiger, Heather, Agius, Phaedra, Bouvier, Nancy, Huberman, Kety, Vanness, Katelynd, Havel, Jonathan J., Sims, Jennifer S., Samstein, Robert M., Mandal, Rajarsi, Tepe, Justin, Ganly, Ian, Ho, Alan L., Riaz, Nadeem, Wong, Richard J., Shukla, Neerav, Chan, Timothy A., Morris, Luc G.T.
Publicado 2019

Sequencing and curation strategies for identifying candidate glioblastoma treatments

por Frank, Mayu O., Koyama, Takahiko, Rhrissorrakrai, Kahn, Robine, Nicolas, Utro, Filippo, Emde, Anne-Katrin, Chen, Bo-Juen, Arora, Kanika, Shah, Minita, Geiger, Heather, Felice, Vanessa, Dikoglu, Esra, Rahman, Sadia, Fang, Alice, Vacic, Vladimir, Bergmann, Ewa A., Vogel, Julia L. Moore, Reeves, Catherine, Khaira, Depinder, Calabro, Anthony, Kim, Duyang, Lamendola-Essel, Michelle F., Esteves, Cecilia, Agius, Phaedra, Stolte, Christian, Boockvar, John, Demopoulos, Alexis, Placantonakis, Dimitris G., Golfinos, John G., Brennan, Cameron, Bruce, Jeffrey, Lassman, Andrew B., Canoll, Peter, Grommes, Christian, Daras, Mariza, Diamond, Eli, Omuro, Antonio, Pentsova, Elena, Orange, Dana E., Harvey, Stephen J., Posner, Jerome B., Michelini, Vanessa V., Jobanputra, Vaidehi, Zody, Michael C., Kelly, John, Parida, Laxmi, Wrzeszczynski, Kazimierz O., Royyuru, Ajay K., Darnell, Robert B.
Publicado 2019

Correction to: Sequencing and curation strategies for identifying candidate glioblastoma treatments

por Frank, Mayu O., Koyama, Takahiko, Rhrissorrakrai, Kahn, Robine, Nicolas, Utro, Filippo, Emde, Anne-Katrin, Chen, Bo-Juen, Arora, Kanika, Shah, Minita, Geiger, Heather, Felice, Vanessa, Dikoglu, Esra, Rahman, Sadia, Fang, Xiaolan, Vacic, Vladimir, Bergmann, Ewa A., Moore Vogel, Julia L., Reeves, Catherine, Khaira, Depinder, Calabro, Anthony, Kim, Duyang, Lamendola-Essel, Michelle F., Esteves, Cecilia, Agius, Phaedra, Stolte, Christian, Boockvar, John, Demopoulos, Alexis, Placantonakis, Dimitris G., Golfinos, John G., Brennan, Cameron, Bruce, Jeffrey, Lassman, Andrew B., Canoll, Peter, Grommes, Christian, Daras, Mariza, Diamond, Eli, Omuro, Antonio, Pentsova, Elena, Orange, Dana E., Harvey, Stephen J., Posner, Jerome B., Michelini, Vanessa V., Jobanputra, Vaidehi, Zody, Michael C., Kelly, John, Parida, Laxmi, Wrzeszczynski, Kazimierz O., Royyuru, Ajay K., Darnell, Robert B.
Publicado 2019

System-wide transcriptome damage and tissue identity loss in COVID-19 patients

por Park, Jiwoon, Foox, Jonathan, Hether, Tyler, Danko, David C., Warren, Sarah, Kim, Youngmi, Reeves, Jason, Butler, Daniel J., Mozsary, Christopher, Rosiene, Joel, Shaiber, Alon, Afshin, Evan E., MacKay, Matthew, Rendeiro, André F., Bram, Yaron, Chandar, Vasuretha, Geiger, Heather, Craney, Arryn, Velu, Priya, Melnick, Ari M., Hajirasouliha, Iman, Beheshti, Afshin, Taylor, Deanne, Saravia-Butler, Amanda, Singh, Urminder, Wurtele, Eve Syrkin, Schisler, Jonathan, Fennessey, Samantha, Corvelo, André, Zody, Michael C., Germer, Soren, Salvatore, Steven, Levy, Shawn, Wu, Shixiu, Tatonetti, Nicholas P., Shapira, Sagi, Salvatore, Mirella, Westblade, Lars F., Cushing, Melissa, Rennert, Hanna, Kriegel, Alison J., Elemento, Olivier, Imielinski, Marcin, Rice, Charles M., Borczuk, Alain C., Meydan, Cem, Schwartz, Robert E., Mason, Christopher E.
Publicado 2022