Structural basis for IL-1α recognition by a modified DNA aptamer that specifically inhibits IL-1α signaling

por Ren, Xiaoming, Gelinas, Amy D., von Carlowitz, Ira, Janjic, Nebojsa, Pyle, Anna Marie
Publicado 2017

Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents

por Rohloff, John C, Gelinas, Amy D, Jarvis, Thale C, Ochsner, Urs A, Schneider, Daniel J, Gold, Larry, Janjic, Nebojsa
Publicado 2014

Modified nucleotides may have enhanced early RNA catalysis

por Wolk, Steven K., Mayfield, Wesley S., Gelinas, Amy D., Astling, David, Guillot, Jessica, Brody, Edward N., Janjic, Nebojsa, Gold, Larry
Publicado 2020

Modified aptamers as reagents to characterize recombinant human erythropoietin products

por Jankowski, Wojciech, Lagassé, H. A. Daniel, Chang, William C., McGill, Joseph, Jankowska, Katarzyna I., Gelinas, Amy D., Janjic, Nebojsa, Sauna, Zuben E.
Publicado 2020

Crystal Structure of Interleukin-6 in Complex with a Modified Nucleic Acid Ligand

por Gelinas, Amy D., Davies, Douglas R., Edwards, Thomas E., Rohloff, John C., Carter, Jeffrey D., Zhang, Chi, Gupta, Shashi, Ishikawa, Yuichi, Hirota, Masao, Nakaishi, Yuichiro, Jarvis, Thale C., Janjic, Nebojsa
Publicado 2014

Broadly neutralizing aptamers to SARS-CoV-2: A diverse panel of modified DNA antiviral agents

por Gelinas, Amy D., Tan, Tiong Kit, Liu, Sai, Jaramillo, Javier G., Chadwick, James, Harding, Adam C., Zhang, Chi, Ream, Brian E., Chase, Chelsea N., Otis, Matthew R., Lee, Thomas, Schneider, Daniel J., James, William S., Janjic, Nebojsa
Publicado 2023

Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies

por Alexaki, Aikaterini, Hettiarachchi, Gaya K., Athey, John C., Katneni, Upendra K., Simhadri, Vijaya, Hamasaki-Katagiri, Nobuko, Nanavaty, Puja, Lin, Brian, Takeda, Kazuyo, Freedberg, Darón, Monroe, Dougald, McGill, Joseph R., Peters, Robert, Kames, Jacob M., Holcomb, David D., Hunt, Ryan C., Sauna, Zuben E., Gelinas, Amy, Janjic, Nebojsa, DiCuccio, Michael, Bar, Haim, Komar, Anton A., Kimchi-Sarfaty, Chava
Publicado 2019

Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus

por Stacey, David, Chen, Lingyan, Stanczyk, Paulina J., Howson, Joanna M. M., Mason, Amy M., Burgess, Stephen, MacDonald, Stephen, Langdown, Jonathan, McKinney, Harriett, Downes, Kate, Farahi, Neda, Peters, James E., Basu, Saonli, Pankow, James S., Tang, Weihong, Pankratz, Nathan, Sabater-Lleal, Maria, de Vries, Paul S., Smith, Nicholas L., Gelinas, Amy D., Schneider, Daniel J., Janjic, Nebojsa, Samani, Nilesh J., Ye, Shu, Summers, Charlotte, Chilvers, Edwin R., Danesh, John, Paul, Dirk S.
Publicado 2022

Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus

por Stacey, David, Chen, Lingyan, Stanczyk, Paulina J., Howson, Joanna M. M., Mason, Amy M., Burgess, Stephen, MacDonald, Stephen, Langdown, Jonathan, McKinney, Harriett, Downes, Kate, Farahi, Neda, Peters, James E., Basu, Saonli, Pankow, James S., Tang, Weihong, Pankratz, Nathan, Sabater-Lleal, Maria, de Vries, Paul S., Smith, Nicholas L., Gelinas, Amy D., Schneider, Daniel J., Janjic, Nebojsa, Samani, Nilesh J., Ye, Shu, Summers, Charlotte, Chilvers, Edwin R., Danesh, John, Paul, Dirk S.
Publicado 2022