Androgen Receptor Activation in Castration-Recurrent Prostate Cancer: The Role of Src-Family and Ack1 Tyrosine Kinases

por Gelman, Irwin H.
Publicado 2014

Pivotal Role of AKAP12 in the Regulation of Cellular Adhesion Dynamics: Control of Cytoskeletal Architecture, Cell Migration, and Mitogenic Signaling

por Akakura, Shin, Gelman, Irwin H.
Publicado 2012

SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesis

por Liu, Yongzhong, Gao, Lingqiu, Gelman, Irwin H
Publicado 2006

Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion

por Sachdev, Sanjay, Bu, Yahao, Gelman, Irwin H
Publicado 2009

Identification of Novel Focal Adhesion Kinase Substrates: Role for FAK in NFκB Signaling

por Dwyer, Sheila Figel, Gao, Lingqiu, Gelman, Irwin H.
Publicado 2015

HIV-1 expression induces cyclin D(1) expression and pRb phosphorylation in infected podocytes: cell-cycle mechanisms contributing to the proliferative phenotype in HIV-associated n...

por Nelson, Peter J, Sunamoto, Masaaki, Husain, Mohammad, Gelman, Irwin H
Publicado 2002

A methyl-sensitive element induces bidirectional transcription in TATA-less CpG island-associated promoters

por Mahpour, Amin, Scruggs, Benjamin S., Smiraglia, Dominic, Ouchi, Toru, Gelman, Irwin H.
Publicado 2018

Role of A-Kinase Anchoring Protein 12 in the Central Nervous System

por Kimura, Shintaro, Lok, Josephine, Gelman, Irwin H., Lo, Eng H., Arai, Ken
Publicado 2023

Src controls castration recurrence of CWR22 prostate cancer xenografts

por Su, Bing, Gillard, Bryan, Gao, Lingqiu, Eng, Kevin H, Gelman, Irwin H
Publicado 2013

Suppression of Chemotaxis by SSeCKS via Scaffolding of Phosphoinositol Phosphates and the Recruitment of the Cdc42 GEF, Frabin, to the Leading Edge

por Ko, Hyun-Kyung, Guo, Li-wu, Su, Bing, Gao, Lingqiu, Gelman, Irwin H.
Publicado 2014

SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts

por Muramatsu, Masashi, Gao, Lingqiu, Peresie, Jennifer, Balderman, Benjamin, Akakura, Shin, Gelman, Irwin H.
Publicado 2017

SSeCKS/Akap12 suppresses metastatic melanoma lung colonization by attenuating Src-mediated pre-metastatic niche crosstalk

por Muramatsu, Masashi, Akakura, Shin, Gao, Lingqiu, Peresie, Jennifer, Balderman, Benjamin, Gelman, Irwin H.
Publicado 2018

Adhesion-mediated cytoskeletal remodeling is controlled by the direct scaffolding of Src from FAK complexes to lipid rafts by SSeCKS/AKAP12

por Su, Bing, Gao, Lingqiu, Meng, Fanjie, Guo, Li-wu, Rothschild, Julian, Gelman, Irwin H.
Publicado 2012

PTEN regulated PI3K-p110 and AKT isoform plasticity controls metastatic prostate cancer progression

por Miller, Karina, Degan, Seamus, Wang, Yanqing, Cohen, Joseph, Ku, Sheng-Yu, Goodrich, David, Gelman, Irwin
Publicado 2023

A Genome-Wide RNAi Screen Identifies FOXO4 as a Metastasis-Suppressor through Counteracting PI3K/AKT Signal Pathway in Prostate Cancer

por Su, Bing, Gao, Lingqiu, Baranowski, Catherine, Gillard, Bryan, Wang, Jianmin, Ransom, Ryan, Ko, Hyun-Kyung, Gelman, Irwin H.
Publicado 2014

Src promotes castration-recurrent prostate cancer through androgen receptor-dependent canonical and non-canonical transcriptional signatures

por Chattopadhyay, Indranil, Wang, Jianmin, Qin, Maochun, Gao, Lingqiu, Holtz, Renae, Vessella, Robert L., Leach, Robert W., Gelman, Irwin H.
Publicado 2016

A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells

por Hehnly, Heidi, Canton, David, Bucko, Paula, Langeberg, Lorene K, Ogier, Leah, Gelman, Irwin, Santana, L Fernando, Wordeman, Linda, Scott, John D
Publicado 2015

Structural environment built by AKAP12+ colon mesenchymal cells drives M2 macrophages during inflammation recovery

por Yang, Jun-Mo, Lee, Hye Shin, Seo, Ji Hae, Park, Ji-Hyeon, Gelman, Irwin H., Lo, Eng H., Kim, Kyu-Won
Publicado 2017

Glucose Drives Growth Factor–Independent Esophageal Cancer Proliferation via Phosphohistidine–Focal Adhesion Kinase Signaling

por Zhang, Jianliang, Gelman, Irwin H., Katsuta, Eriko, Liang, Yuanzi, Wang, Xue, Li, Jun, Qu, Jun, Yan, Li, Takabe, Kazuaki, Hochwald, Steven N.
Publicado 2019

VGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast Cancer

por Zhang, Yinglong, Shen, He, Withers, Henry G., Yang, Nuo, Denson, Kayla E., Mussell, Ashley L., Truskinovsky, Alexander, Fan, Qingyu, Gelman, Irwin H., Frangou, Costa, Zhang, Jianmin
Publicado 2017