Structure-Based Design of Biologically Active Compounds

por Gemma, Sandra
Publicado 2020

Broad inhibition of plasmodium falciparum cytoadherence by (+)-epigallocatechin gallate

por Patil, Pradeep R, Gemma, Sandra, Campiani, Giuseppe, Craig, Alister G
Publicado 2011

Computational Tool for Fast in silico Evaluation of hERG K(+) Channel Affinity

por Chemi, Giulia, Gemma, Sandra, Campiani, Giuseppe, Brogi, Simone, Butini, Stefania, Brindisi, Margherita
Publicado 2017

A Therapeutic Perspective of HDAC8 in Different Diseases: An Overview of Selective Inhibitors

por Fontana, Anna, Cursaro, Ilaria, Carullo, Gabriele, Gemma, Sandra, Butini, Stefania, Campiani, Giuseppe
Publicado 2022

Dopamine D3 Receptor Antagonists as Potential Therapeutics for the Treatment of Neurological Diseases

por Maramai, Samuele, Gemma, Sandra, Brogi, Simone, Campiani, Giuseppe, Butini, Stefania, Stark, Holger, Brindisi, Margherita
Publicado 2016

A Repurposing Approach for Uncovering the Anti-Tubercular Activity of FDA-Approved Drugs with Potential Multi-Targeting Profiles

por Battah, Basem, Chemi, Giulia, Butini, Stefania, Campiani, Giuseppe, Brogi, Simone, Delogu, Giovanni, Gemma, Sandra
Publicado 2019

Covalent Reversible Inhibitors of Cysteine Proteases Containing the Nitrile Warhead: Recent Advancement in the Field of Viral and Parasitic Diseases

por Brogi, Simone, Ibba, Roberta, Rossi, Sara, Butini, Stefania, Calderone, Vincenzo, Gemma, Sandra, Campiani, Giuseppe
Publicado 2022

Polypharmacological Approaches for CNS Diseases: Focus on Endocannabinoid Degradation Inhibition

por Papa, Alessandro, Pasquini, Silvia, Contri, Chiara, Gemma, Sandra, Campiani, Giuseppe, Butini, Stefania, Varani, Katia, Vincenzi, Fabrizio
Publicado 2022

The green chemistry of chalcones: Valuable sources of privileged core structures for drug discovery

por Marotta, Ludovica, Rossi, Sara, Ibba, Roberta, Brogi, Simone, Calderone, Vincenzo, Butini, Stefania, Campiani, Giuseppe, Gemma, Sandra
Publicado 2022

In silico study of subtilisin-like protease 1 (SUB1) from different Plasmodium species in complex with peptidyl-difluorostatones and characterization of potent pan-SUB1 inhibitors

por Brogi, Simone, Giovani, Simone, Brindisi, Margherita, Gemma, Sandra, Novellino, Ettore, Campiani, Giuseppe, Blackman, Michael J., Butini, Stefania
Publicado 2016

Development of Quinazolinone Derivatives as Modulators of Virulence Factors of Pseudomonas aeruginosa Cystic Fibrosis Strains

por Carullo, Gabriele, Di Bonaventura, Giovanni, Rossi, Sara, Lupetti, Veronica, Tudino, Valeria, Brogi, Simone, Butini, Stefania, Campiani, Giuseppe, Gemma, Sandra, Pompilio, Arianna
Publicado 2023

In Vitro and In Silico Analyses of New Cinnamid and Rosmarinic Acid-Derived Compounds Biosynthesized in Escherichia coli as Leishmania amazonensis Arginase Inhibitors

por Come, Julio Abel Alfredo dos Santos Simone, Zhuang, Yibin, Li, Tianzhen, Brogi, Simone, Gemma, Sandra, Liu, Tao, da Silva, Edson Roberto
Publicado 2022

Identification of Novel 3-Hydroxy-pyran-4-One Derivatives as Potent HIV-1 Integrase Inhibitors Using in silico Structure-Based Combinatorial Library Design Approach

por Sirous, Hajar, Chemi, Giulia, Gemma, Sandra, Butini, Stefania, Debyser, Zeger, Christ, Frauke, Saghaie, Lotfollah, Brogi, Simone, Fassihi, Afshin, Campiani, Giuseppe, Brindisi, Margherita
Publicado 2019

Total Synthesis of the Natural Chalcone Lophirone E, Synthetic Studies toward Benzofuran and Indole-Based Analogues, and Investigation of Anti-Leishmanial Activity

por Pozzetti, Luca, Ibba, Roberta, Rossi, Sara, Taglialatela-Scafati, Orazio, Taramelli, Donatella, Basilico, Nicoletta, D’Alessandro, Sarah, Parapini, Silvia, Butini, Stefania, Campiani, Giuseppe, Gemma, Sandra
Publicado 2022

Crystal structures of Schistosoma mansoni histone deacetylase 8 reveal a novel binding site for allosteric inhibitors

por Saccoccia, Fulvio, Pozzetti, Luca, Gimmelli, Roberto, Butini, Stefania, Guidi, Alessandra, Papoff, Giuliana, Giannaccari, Marialaura, Brogi, Simone, Scognamiglio, Viviana, Gemma, Sandra, Ruberti, Giovina, Campiani, Giuseppe
Publicado 2022

Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking

por Brindisi, Margherita, Brogi, Simone, Relitti, Nicola, Vallone, Alessandra, Butini, Stefania, Gemma, Sandra, Novellino, Ettore, Colotti, Gianni, Angiulli, Gabriella, Di Chiaro, Francesco, Fiorillo, Annarita, Ilari, Andrea, Campiani, Giuseppe
Publicado 2015

Design and Synthesis of Oligopeptidic Parvulin Inhibitors

por Relitti, Nicola, Prasanth Saraswati, A., Carullo, Gabriele, Papa, Alessandro, Monti, Alessandra, Benedetti, Rosaria, Passaro, Eugenia, Brogi, Simone, Calderone, Vincenzo, Butini, Stefania, Gemma, Sandra, Altucci, Lucia, Campiani, Giuseppe, Doti, Nunzianna
Publicado 2022

Extra Virgin Olive Oil Extracts of Indigenous Southern Tuscany Cultivar Act as Anti-Inflammatory and Vasorelaxant Nutraceuticals

por Pozzetti, Luca, Ferrara, Francesca, Marotta, Ludovica, Gemma, Sandra, Butini, Stefania, Benedusi, Mascia, Fusi, Fabio, Ahmed, Amer, Pomponi, Serena, Ferrari, Stefano, Perini, Matteo, Ramunno, Anna, Pepe, Giacomo, Campiglia, Pietro, Valacchi, Giuseppe, Carullo, Gabriele, Campiani, Giuseppe
Publicado 2022

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–5

por Mangoni, Arduino A., Eynde, Jean Jacques Vanden, Jampilek, Josef, Hadjipavlou-Litina, Dimitra, Liu, Hong, Reynisson, Jóhannes, Sousa, Maria Emília, Gomes, Paula A. C., Prokai-Tatrai, Katalin, Tuccinardi, Tiziano, Sabatier, Jean-Marc, Luque, F. Javier, Rautio, Jarkko, Karaman, Rafik, Vasconcelos, M. Helena, Gemma, Sandra, Galdiero, Stefania, Hulme, Christopher, Collina, Simona, Gütschow, Michael, Kokotos, George, Siciliano, Carlo, Capasso, Raffaele, Agrofoglio, Luigi A., Ragno, Rino, Muñoz-Torrero, Diego
Publicado 2019

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–6

por Vanden Eynde, Jean Jacques, Mangoni, Arduino A., Rautio, Jarkko, Leprince, Jérôme, Azuma, Yasu-Taka, García-Sosa, Alfonso T., Hulme, Christopher, Jampilek, Josef, Karaman, Rafik, Li, Wei, Gomes, Paula A. C., Hadjipavlou-Litina, Dimitra, Capasso, Raffaele, Geronikaki, Athina, Cerchia, Laura, Sabatier, Jean-Marc, Ragno, Rino, Tuccinardi, Tiziano, Trabocchi, Andrea, Winum, Jean-Yves, Luque, F. Javier, Prokai-Tatrai, Katalin, Spetea, Mariana, Gütschow, Michael, Kosalec, Ivan, Guillou, Catherine, Vasconcelos, M. Helena, Kokotos, George, Rastelli, Giulio, de Sousa, Maria Emília, Manera, Clementina, Gemma, Sandra, Mangani, Stefano, Siciliano, Carlo, Galdiero, Stefania, Liu, Hong, Scott, Peter J. H., de los Ríos, Cristóbal, Agrofoglio, Luigi A., Collina, Simona, Guedes, Rita C., Muñoz-Torrero, Diego
Publicado 2019