Chemical space docking enables large-scale structure-based virtual screening to discover ROCK1 kinase inhibitors

por Beroza, Paul, Crawford, James J., Ganichkin, Oleg, Gendelev, Leo, Harris, Seth F., Klein, Raphael, Miu, Anh, Steinbacher, Stefan, Klingler, Franca-Maria, Lemmen, Christian
Publicado 2022

Zebrafish behavioural profiling identifies GABA and serotonin receptor ligands related to sedation and paradoxical excitation

por McCarroll, Matthew N., Gendelev, Leo, Kinser, Reid, Taylor, Jack, Bruni, Giancarlo, Myers-Turnbull, Douglas, Helsell, Cole, Carbajal, Amanda, Rinaldi, Capria, Kang, Hye Jin, Gong, Jung Ho, Sello, Jason K., Tomita, Susumu, Peterson, Randall T., Keiser, Michael J., Kokel, David
Publicado 2019

Zebrafish behavioral profiling identifies multi-target antipsychotic-like compounds

por Bruni, Giancarlo, Rennekamp, Andrew J., Velenich, Andrea, McCarroll, Matthew, Gendelev, Leo, Fertsch, Ethan, Taylor, Jack, Lakhani, Parth, Lensen, Dennis, Evron, Tama, Lorello, Paul J., Huang, Xi-Ping, Kolczewski, Sabine, Carey, Galen, Caldarone, Barbara J., Prinssen, Eric, Roth, Bryan L., Keiser, Michael J., Peterson, Randall T., Kokel, David
Publicado 2016