Bioinformatics and computational approaches for analyzing patient-derived disease models in cancer research

por Gendoo, Deena M.A.
Publicado 2020

Origins and Evolution of the HET-s Prion-Forming Protein: Searching for Other Amyloid-Forming Solenoids

por Gendoo, Deena M. A., Harrison, Paul M.
Publicado 2011

The Landscape of the Prion Protein's Structural Response to Mutation Revealed by Principal Component Analysis of Multiple NMR Ensembles

por Gendoo, Deena M. A., Harrison, Paul M.
Publicado 2012

MM2S: personalized diagnosis of medulloblastoma patients and model systems

por Gendoo, Deena M.A., Haibe-Kains, Benjamin
Publicado 2016

A subgroup of microRNAs defines PTEN-deficient, triple-negative breast cancer patients with poorest prognosis and alterations in RB1, MYC, and Wnt signaling

por Wang, Dong-Yu, Gendoo, Deena M. A., Ben-David, Yaacov, Woodgett, James R., Zacksenhaus, Eldad
Publicado 2019

PrionHome: A Database of Prions and Other Sequences Relevant to Prion Phenomena

por Harbi, Djamel, Parthiban, Marimuthu, Gendoo, Deena M. A., Ehsani, Sepehr, Kumar, Manish, Schmitt-Ulms, Gerold, Sowdhamini, Ramanathan, Harrison, Paul M.
Publicado 2012

MetaGxData: Clinically Annotated Breast, Ovarian and Pancreatic Cancer Datasets and their Use in Generating a Multi-Cancer Gene Signature

por Gendoo, Deena M. A., Zon, Michael, Sandhu, Vandana, Manem, Venkata S. K., Ratanasirigulchai, Natchar, Chen, Gregory M., Waldron, Levi, Haibe-Kains, Benjamin
Publicado 2019

The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

por Kime, Louise, Vincent, Helen A., Gendoo, Deena M. A., Jourdan, Stefanie S., Fishwick, Colin W. G., Callaghan, Anastasia J., McDowall, Kenneth J.
Publicado 2015

Erratum: The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

por Kime, Louise, Vincent, Helen A., Gendoo, Deena M. A., Jourdan, Stefanie S., Fishwick, Colin W. G., Callaghan, Anastasia J., McDowall, Kenneth J.
Publicado 2015

A temporal in vivo catalog of chromatin accessibility and expression profiles in pineoblastoma reveals a prevalent role for repressor elements

por Idriss, Salam, Hallal, Mohammad, El-Kurdi, Abdullah, Zalzali, Hasan, El-Rassi, Inaam, Ehli, Erik A., Davis, Christel M., Chung, Philip E.D., Gendoo, Deena M.A., Zacksenhaus, Eldad, Saab, Raya, Khoueiry, Pierre
Publicado 2023

Computational pharmacogenomic screen identifies drugs that potentiate the anti-breast cancer activity of statins

por van Leeuwen, Jenna E., Ba-Alawi, Wail, Branchard, Emily, Cruickshank, Jennifer, Schormann, Wiebke, Longo, Joseph, Silvester, Jennifer, Gross, Peter L., Andrews, David W., Cescon, David W., Haibe-Kains, Benjamin, Penn, Linda Z., Gendoo, Deena M. A.
Publicado 2022

Public data and open source tools for multi-assay genomic investigation of disease

por Kannan, Lavanya, Ramos, Marcel, Re, Angela, El-Hachem, Nehme, Safikhani, Zhaleh, Gendoo, Deena M.A., Davis, Sean, Gomez-Cabrero, David, Castelo, Robert, Hansen, Kasper D., Carey, Vincent J., Morgan, Martin, Culhane, Aedín C., Haibe-Kains, Benjamin, Waldron, Levi
Publicado 2016

Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer

por Gendoo, Deena M. A., Denroche, Robert E., Zhang, Amy, Radulovich, Nikolina, Jang, Gun Ho, Lemire, Mathieu, Fischer, Sandra, Chadwick, Dianne, Lungu, Ilinca M., Ibrahimov, Emin, Cao, Ping-Jiang, Stein, Lincoln D., Wilson, Julie M., Bartlett, John M. S., Tsao, Ming-Sound, Dhani, Neesha, Hedley, David, Gallinger, Steven, Haibe-Kains, Benjamin
Publicado 2019

The anti-tumour activity of DNA methylation inhibitor 5-aza-2′-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress

por Gleneadie, Hannah J., Baker, Amy H., Batis, Nikolaos, Bryant, Jennifer, Jiang, Yao, Clokie, Samuel J.H., Mehanna, Hisham, Garcia, Paloma, Gendoo, Deena M.A., Roberts, Sally, Burley, Megan, Molinolo, Alfredo A., Gutkind, J. Silvio, Scheven, Ben A., Cooper, Paul R., Parish, Joanna L., Khanim, Farhat L., Wiench, Malgorzata
Publicado 2021

Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy

por Chung, Philip E. D., Gendoo, Deena M. A., Ghanbari-Azarnier, Ronak, Liu, Jeff C., Jiang, Zhe, Tsui, Jennifer, Wang, Dong-Yu, Xiao, Xiao, Li, Bryan, Dubuc, Adrian, Shih, David, Remke, Marc, Ho, Ben, Garzia, Livia, Ben-David, Yaacov, Kang, Seok-Gu, Croul, Sidney, Haibe-Kains, Benjamin, Huang, Annie, Taylor, Michael D., Zacksenhaus, Eldad
Publicado 2020